Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,075

Sort By: Relevance

$165K - $227K *

Unlock your potential as you develop cutting-edge AI algorithms for real-time audio processing. Collaborate with experts to enhance audio experiences through innovative source separation techniques an...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Consumer Technology

$80K - $100K *

Join a dynamic team to build lasting client relationships, oversee accounts, and deliver tailored pest management solutions. Leverage industry expertise and innovative tools to drive sales and ensure...

Today

  •   Less than 5 years exp.  •   Staffing

$100K - $196K *

Unlock potential by validating advanced NLP and AI models, ensuring compliance and performance. Collaborate across teams in a dynamic environment, leveraging your quantitative expertise to drive impac...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $110K *

Empower clinical excellence by leading a team of Care Guide RNs while managing a caseload of active members. Drive performance, coaching, and quality metrics in a hybrid role that blends leadership wi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$113K - $146K *

Empower innovation by leading the design and implementation of advanced technology solutions. Collaborate with teams to enhance operational efficiency, automate processes, and improve user experiences...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Transportation

$160K - $220K *

Join us to lead and expand our Analytics practice, driving data insights and marketing strategies while managing a talented team in a dynamic and evolving digital landscape...

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Reposted today

  •   8 - 10 years exp.  •   Media

$70K - $100K *

Champion new business growth by identifying and converting prospects into clients. Own the full sales cycle, leveraging data insights and consultative selling to drive urgency and deliver tailored sol...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Staffing

$91K - $129K *

Champion your career by managing and enhancing Salesforce environments. Collaborate with cross-functional teams to streamline workflows, support users, and drive impactful projects that scale business...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Empower excellence in maintenance leadership, driving performance and safety while managing skilled teams in a dynamic manufacturing environment. Collaborate across departments to achieve key objectiv...

Reposted today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Transform the Ingot Department by leading maintenance teams, ensuring safety and productivity, and driving reliability and performance through effective management and strategic initiatives within a d...

Reposted today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Unlock potential by driving commercial and industrial water treatment sales. Manage customer accounts, develop strategies, and actively participate in trade shows, ensuring robust client relationships...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $203K *

Transform the Unity platform for Android ecosystems by optimizing performance and enabling seamless deployment across devices. Collaborate with teams to enhance software capabilities and drive innovat...

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Today

  •   5 - 7 years exp.  •   Information Technology

$92K - $166K *

Empower a dynamic team by leading high voltage transmission line projects, ensuring quality design and execution while fostering collaboration and innovation in a fast-paced environment. Drive client...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Technical Services

$80K - $95K *

Advance quality improvement initiatives by managing diverse health services, ensuring compliance with contract deliverables, and leading a dedicated team to achieve operational excellence and strategi...

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Empower your career by driving strategic partnerships and revenue growth. Collaborate with leadership to implement alliance strategies, enhance partner relationships, and promote ADP's value propositi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $150K *

Empower ecommerce brands to leverage AI marketing tools effectively, guiding users to understand and implement solutions that enhance their growth strategies while fostering confidence in AI capabilit...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Enterprise Technology

$175K - $225K *

Drive strategic growth by enhancing partnerships within the senior living sector. Lead a team to optimize provider performance, boost retention, and elevate customer satisfaction, ensuring families ha...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in innovative quality engineering projects to enhance product quality in wood cabinetry manufacturing. Manage projects from concept to implementation, ensuring best practices are adopt...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$98K - $109K *

Join a team that's dedicated to optimizing IT operations and ensuring compliance. You'll manage daily IT tasks, support security initiatives, and collaborate on maintaining audit readiness, all while...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$162K - $225K *

Join a team that's shaping the future of fintech through M&A, fundraising, and strategic projects. Collaborate with executives to drive impactful decisions and build corporate development capabilities...

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Today

  •   5 - 7 years exp.  •   Finance & Insurance

$105K - $141K *

Champion advanced security initiatives by leading Red Team efforts to identify vulnerabilities and enhance protection across enterprise systems through penetration testing and adversarial emulation, w...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$135K - $180K *

Transform organizational effectiveness as a strategic HR leader, driving talent development and workforce insights across a vast retail network. Collaborate with executives to enhance leadership capab...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$135K - $180K *

Elevate your career as a strategic HR leader, driving talent initiatives and organizational effectiveness across a large retail network while partnering with senior executives to enhance business outc...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$125K - $200K *

Shape the future of healthcare by leading value-based care initiatives, managing client engagements, and driving strategic recommendations that enhance quality and reduce costs. Collaborate with diver...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Lead strategic sales initiatives in the SLED sector, driving revenue growth and building executive relationships. Manage complex sales cycles, mentor junior staff, and represent the company at industr...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.