Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$130K - $156K *

Join us to lead SAP data migration initiatives, designing enterprise-grade strategies and delivering integrated planning solutions. Collaborate across project lifecycles, ensuring client success throu...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$132K - $302K *

Empower large-scale Salesforce Life Sciences programs by owning the solution architecture vision. Collaborate with business and technical teams, mentor talent, and drive innovation while ensuring alig...

Reposted yesterday

  •   8 - 10 years exp.  •   Business Services

$134K - $201K *

Optimize the future of advanced therapies by driving complex CDMO deals, managing stakeholder relationships, and leveraging deep CGT expertise. Collaborate cross-functionally to promote growth and sha...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$130K - $145K *

Join a dynamic team to design, develop, and maintain full-stack applications, leveraging Python, AWS, and Terraform. Lead projects from ideation to deployment while mentoring junior engineers and ensu...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$94K - $266K *

Elevate strategic initiatives by driving growth and operational strategies for the Americas. Collaborate with leadership to solve complex business challenges and implement impactful solutions across d...

Reposted yesterday

  •   Less than 5 years exp.  •   Business Services

$88K - $147K *

Engage with a dynamic team to lead and develop property claims adjusters, enhancing their skills in coverage interpretation and customer communication while adapting to evolving claims processes and t...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Lead and inspire a dynamic team in delivering innovative land development projects. Drive project success through technical guidance, client management, and strategic oversight while fostering collabo...

Yesterday

  •   8 - 10 years exp.  •   Technical Services

$95K - $115K *

Lead the charge in delivering innovative land development projects while mentoring a dynamic team of engineers and technicians. Drive client relationships and ensure high-quality solutions for diverse...

Yesterday

  •   8 - 10 years exp.  •   Technical Services

$160K - $180K *

Join a team that's driving client success by managing strategic relationships and ensuring the financial health of key accounts. Leverage your expertise to bridge business goals with technical solutio...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$135K - $148K *

Drive the successful delivery of complex enterprise projects, ensuring timely execution and high-quality standards. Collaborate cross-functionally to meet client objectives and enhance project managem...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $150K *

Drive your career with a leading petroleum transport team, ensuring timely delivery of products while maintaining high safety standards and exceptional customer service. Join a dynamic environment wit...

Yesterday

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$115K - $140K *

Drive operational excellence and commercial readiness in a dynamic biotech environment. Collaborate cross-functionally to support launch activities, data management, and performance reporting, ensurin...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$225K - $275K *

Optimize quality assurance processes to ensure compliance with regulatory standards and drive improvements across all operations. Lead a talented team to establish and maintain an effective Quality Ma...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $185K *

Architect comprehensive clinical supply strategies for global trials. Collaborate across functional teams to secure timely, compliant drug supply while managing risks and inventory effectively, ensuri...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Transform global supply chain operations by leading strategic sourcing, enhancing supplier performance, and establishing resilient logistics across multiple regions. Drive collaboration between teams...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$90K - $110K *

Lead customer engagement by driving acquisition, relationship management, and sales growth. Collaborate with internal teams to enhance customer satisfaction and product adoption in a dynamic, fast-pac...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Oversee and optimize customer service operations, leading a dynamic team to enhance client satisfaction and streamline processes within a vital community support program. Drive strategic initiatives a...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by driving research in prediction markets, developing alpha signals, and collaborating through the entire model implementation process. Guide projects from data analysis to live tradi...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$108K - $130K *

Lead product security and compliance initiatives, ensuring clients meet regulatory standards across diverse sectors. Drive client engagement, deliver assessments, and enhance cybersecurity resilience...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$180K - $220K *

Advance global procurement initiatives by leading sourcing strategies for MRO and automotive parts. Drive operational excellence, enhance supplier relationships, and ensure compliance while achieving...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Transportation

$95K - $115K *

Elevate engineering processes by developing innovative software and AI solutions. Collaborate with a dynamic team to transform concepts into scalable applications, leveraging modern web technologies a...

Reposted yesterday

  •   Less than 5 years exp.  •   Staffing

$90K - $125K *

Drive growth in the Data Center market by leading sales strategies, developing key relationships, and executing innovative initiatives to achieve market leadership in the West region. Shape the future...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$89K - $129K *

Oversee quality assurance and field inspections for solar PV and energy storage projects, ensuring compliance and safety. Serve as the on-site representative for escalations, audits, and disaster reco...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$70K - $205K *

Contribute to building modern web applications by leveraging your expertise in React and TypeScript. Collaborate with cross-functional teams to deliver high-quality software while ensuring maintainabi...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$73K - $106K *

Engage in the development and execution of training programs, providing expert guidance and support to enhance operational efficiency and compliance across Fleet Development initiatives while fosterin...

Yesterday

  •   Less than 5 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.