Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$98K - $115K *

Transform customer support by managing AI operations and content quality. Drive improvements in AI agent performance, oversee Help Center accuracy, and ensure seamless content delivery for enhanced cu...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $150K *

Unlock potential by leading software implementation projects, applying Agile methodologies, and ensuring client satisfaction through effective communication and collaboration with cross-functional tea...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Transform enterprise service delivery by leading cross-center operations, enhancing efficiency, and ensuring high-quality IT services across multiple locations. Drive initiatives that improve performa...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Information Technology

$94K - $293K *

Transform utilities finance operations by leveraging SAP FI-CA expertise to enhance customer accounting, streamline processes, and lead innovative projects that drive efficiency and compliance across...

Yesterday

  •   5 - 7 years exp.  •   Business Services

$135K - $180K *

Lead strategic HR initiatives across 600+ stores, enhancing leadership capability and organizational effectiveness while driving talent development and engagement in a dynamic retail environment...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$100K - $120K *

Unlock potential by providing expert XBRL project support, ensuring compliance and accuracy in financial reporting for diverse clients while collaborating across teams to enhance project delivery and...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Consumer Technology

$170K - $200K *

Shape the future of medical affairs by leading a high-performing team of Medical Science Liaisons, driving scientific engagement, and ensuring strategic alignment with healthcare needs while fostering...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Grow your career with us by leading strategic sales initiatives, building relationships with key accounts, and driving business growth in the employer-sponsored health sector. Adapt and thrive in a dy...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Accelerate progress at a leading telecom program by driving automation in engineering activities. Collaborate with cross-functional teams to deliver innovative solutions while managing scope, timeline...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Staffing

$159K - $279K *

Lead the charge in driving transparency and accountability across product portfolios. Collaborate with cross-functional teams to enhance risk management, governance, and operational effectiveness whil...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$108K - $180K *

Join a team that's dedicated to enhancing non-clinical product performance through data-driven insights. Lead KPI optimization and collaborate with stakeholders to improve user experiences across vari...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Join a dynamic team to drive sales growth in the US SME market, owning the full sales cycle and translating complex fintech solutions into clear business value for diverse clients. Collaborate across...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $200K *

Drive impactful renewable energy transactions by leveraging financial modeling and structuring expertise. Collaborate with a dynamic team to support capital solutions in tax equity and preferred equit...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$180K - $220K *

Join a team that partners with leaders to enhance organizational performance, drive employee engagement, and implement talent development initiatives in a fast-paced, global environment while supporti...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$300K - $350K *

Transform enterprise sales by expanding Fortune 100 accounts across North America. Collaborate with cross-functional teams to drive growth, enhance customer relationships, and leverage a unique cybers...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$172K - $229K *

Join a dynamic team to enhance autonomous vehicle performance through innovative software tools and metrics. Collaborate cross-functionally to drive technical strategy and ensure data quality, contrib...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Transportation

$106K - $146K *

Accelerate sales growth by engaging clients, shaping strategies, and delivering tailored solutions through collaboration with technical teams, ensuring customer satisfaction and fostering long-term re...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$67K - $107K *

Join a team that's dedicated to optimizing patient transfer logistics and enhancing care continuity. Collaborate with healthcare professionals to ensure timely access and appropriate bed assignments w...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$115K - $173K *

Transform operational excellence by driving compliance and standardization across Plasma Procurement. Collaborate with leaders to enhance processes, implement Lean practices, and foster a culture of c...

RemoteRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in designing and implementing enterprise-grade data archival solutions. Oversee end-to-end delivery, ensuring compliance with security standards while collaborating across teams to opt...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $165K *

Drive the development and continuous improvement of a unified Quality Management System across global manufacturing sites, ensuring compliance, scalability, and alignment with ISO standards while coll...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$142K - $228K *

Join a team that's shaping the future of corporate governance and compliance! In this role, you'll provide strategic legal guidance, mitigate risks, and ensure adherence to laws, driving operational e...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$312K - $446K *

Lead a high-performing team to drive strategic growth in defense and intelligence markets. Oversee opportunity identification, partner engagement, and pipeline development, ensuring disciplined execut...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Information Technology

$100K - $120K *

Transform patient care by overseeing pharmaceutical services, ensuring safe medication practices, and providing clinical support across diverse patient populations. Lead a team to enhance drug therapy...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive building performance and energy efficiency by conducting assessments, audits, and evaluations for diverse properties. Collaborate with clients to enhance sustainability and reduce operational co...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.