Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$150K - $180K *

Transform global supply chain operations by leading strategic sourcing, enhancing supplier performance, and establishing resilient logistics across multiple regions. Drive collaboration between teams...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$90K - $110K *

Lead customer engagement by driving acquisition, relationship management, and sales growth. Collaborate with internal teams to enhance customer satisfaction and product adoption in a dynamic, fast-pac...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Oversee and optimize customer service operations, leading a dynamic team to enhance client satisfaction and streamline processes within a vital community support program. Drive strategic initiatives a...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by driving research in prediction markets, developing alpha signals, and collaborating through the entire model implementation process. Guide projects from data analysis to live tradi...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$108K - $130K *

Lead product security and compliance initiatives, ensuring clients meet regulatory standards across diverse sectors. Drive client engagement, deliver assessments, and enhance cybersecurity resilience...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$180K - $220K *

Advance global procurement initiatives by leading sourcing strategies for MRO and automotive parts. Drive operational excellence, enhance supplier relationships, and ensure compliance while achieving...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Transportation

$95K - $115K *

Elevate engineering processes by developing innovative software and AI solutions. Collaborate with a dynamic team to transform concepts into scalable applications, leveraging modern web technologies a...

Reposted yesterday

  •   Less than 5 years exp.  •   Staffing

$90K - $125K *

Drive growth in the Data Center market by leading sales strategies, developing key relationships, and executing innovative initiatives to achieve market leadership in the West region. Shape the future...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$89K - $129K *

Oversee quality assurance and field inspections for solar PV and energy storage projects, ensuring compliance and safety. Serve as the on-site representative for escalations, audits, and disaster reco...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$70K - $205K *

Contribute to building modern web applications by leveraging your expertise in React and TypeScript. Collaborate with cross-functional teams to deliver high-quality software while ensuring maintainabi...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$73K - $106K *

Engage in the development and execution of training programs, providing expert guidance and support to enhance operational efficiency and compliance across Fleet Development initiatives while fosterin...

Yesterday

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$120K - $145K *

Explore the forefront of hematology/oncology as you engage with healthcare professionals, providing critical scientific insights and fostering relationships to support ADCT's innovative products and p...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$173K - $290K *

Lead the measurement strategy for platform impact, defining metrics and evaluations that drive actionable insights. Collaborate with engineering to operationalize data infrastructure, ensuring quality...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$80K - $95K *

Analyze and interpret complex data to drive strategic decision-making. Collaborate with experts to develop algorithms and visualizations, ensuring data integrity and providing actionable insights for...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Analyze and visualize data to support strategic decision-making. Collaborate with experts to ensure data integrity and develop algorithms. Drive insights through programming and trend analysis in a dy...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$170K - $187K *

Lead and manage clinical trials, ensuring compliance with protocols and regulations. Collaborate with cross-functional teams to achieve study milestones, maintain data quality, and resolve operational...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive impactful field marketing strategies across EMEA, collaborating with sales and stakeholders to execute integrated campaigns that enhance brand visibility and generate demand, while optimizing pe...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$104K - $136K *

Deliver impactful IAM solutions by managing program roadmaps, coordinating cross-functional teams, and leveraging AI tools to enhance identity and access management processes. Drive collaboration and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$97K - $131K *

Lead a dynamic sales strategy by managing key accounts and partnerships. Drive revenue growth through effective relationship building and strategic planning while achieving ambitious sales targets in...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Lead the charge in transforming construction management through digital delivery. Collaborate with leadership to set strategic direction, enhance project efficiency, and drive innovation across teams...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Real Estate & Construction

$170K - $195K *

Join a team that's dedicated to optimizing global power generation operations. You'll support fleet management, enhance O&M standards, and drive continuous improvement initiatives across a diverse por...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $124K *

Join a team that's dedicated to enhancing Fire Life Safety programs for the FAA. Leverage your expertise in fire protection engineering to support compliance, develop standards, and conduct assessment...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Technical Services

$131K - $237K *

Shape secure, scalable cloud solutions across AWS, Azure, OCI, and GCP. Collaborate with teams to automate deployments, enhance cloud operations, and mentor engineers while supporting mission-critical...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Technical Services

$61K - $122K *

Join a team dedicated to advancing cancer diagnostics by overseeing EHR HL7 interfaces, providing technical support, and leading integration projects. Collaborate with stakeholders to ensure seamless...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$82K - $149K *

Champion a team of call center agents, ensuring high-quality service delivery and compliance. Provide clinical oversight for at-risk cases while driving operational excellence and fostering a supporti...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Technical Services

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.