Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$171K - $248K *

Lead a dynamic engineering team to enhance infrastructure and networking, driving user-focused product development while fostering collaboration and operational excellence across the organization...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$150K - $200K *

Develop and maintain robust data pipelines and models, collaborating with cross-functional teams to enhance data practices and ensure quality. Drive modernization efforts in data engineering, optimizi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Drive client success by managing relationships, enhancing satisfaction, and identifying growth opportunities. Collaborate with internal teams to deliver exceptional service and exceed client expectati...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Empower healthcare technology by enhancing clinical systems and integrations. Collaborate with IT and business stakeholders to optimize workflows, manage projects, and ensure system performance across...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$148K - $222K *

Drive clinical adoption and enhance partnerships by leading a high-performing Medical Science Liaison team. Collaborate with sales and medical teams to educate stakeholders, influence decision-making...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Explore the dynamic role of a Program Manager, overseeing end-to-end data collection programs. Drive operational excellence, client satisfaction, and strategic execution in a fast-paced environment, e...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Lead the charge in transforming agency operations by ensuring seamless onboarding and mastery of our all-in-one AdTech platform, bridging technical capabilities with real-world execution for impactful...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $150K *

Elevate your career by leading product operations, enhancing processes, and driving AI adoption. Collaborate with cross-functional teams to optimize product delivery and analytics, ensuring seamless c...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$194K - $266K *

Lead the charge in driving commercial growth by securing high-value partnerships and expanding market presence. Mentor a dynamic team while executing strategic initiatives that enhance client relation...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Explore innovative solutions as a Senior Mobile Engineer, leading the design and architecture of mission-critical apps that empower our delivery fleet and operations teams, ensuring reliability and ef...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$100K - $120K *

Empower quality assurance excellence by leading inspections across North America, ensuring critical infrastructure meets project standards. Collaborate with suppliers and teams to mitigate risks and d...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Optimize physical security applications and operations. Lead system management, support incident response, and enhance security measures across the enterprise. Collaborate with stakeholders to ensure...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Take ownership of a high-performing team in Client Operations, driving service quality and continuous improvement. Collaborate across functions to enhance client experience and operational efficiency...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$133K - $197K *

Drive impactful research by leading technical evaluations and benchmarks in AI. Collaborate with diverse stakeholders to ensure principled guidance that integrates social and technical considerations...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Empower your career by driving sales in SLED accounts, crafting strategic plans, and building executive relationships to achieve sales goals while promoting industry-leading security solutions...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$85K - $109K *

Join us to lead a Salesforce centralization initiative, merging environments and enhancing workflows. Collaborate with stakeholders to create scalable solutions, ensuring a secure and maintainable Sal...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$80K - $95K *

Elevate your marketing career by leading integrated organic campaigns that drive engagement and revenue growth. Collaborate cross-functionally to optimize strategies across social media, email, and ac...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$250K - $300K *

Partner with us to provide expert breast imaging interpretation in a fully remote setting. Enjoy flexible scheduling and a supportive team environment while contributing to exceptional patient care ac...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Unlock your potential as you support impactful traffic and ITS projects, collaborating with a dynamic team to deliver high-quality engineering solutions that shape communities across the Midwest and S...

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$77K - $108K *

Join a dynamic team to design and implement high-performance AI infrastructure solutions, ensuring client satisfaction through expert delivery and support of complex compute and storage systems for en...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $135K *

Lead the charge in full-funnel paid social strategy, execution, and optimization for high-growth clients. Collaborate with teams to deliver integrated marketing solutions and drive measurable business...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$170K - $200K *

Lead technical direction for a healthcare data team, driving architectural decisions and cross-team initiatives to enhance compliance and operational efficiency. Elevate team performance while solving...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$183K - $216K *

Unlock your potential by leading data science initiatives that drive impactful decision-making and enhance analytical frameworks across teams, ensuring rigorous performance standards and scalable self...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$99K - $169K *

Unlock potential by providing expert consulting on accounting methods, managing client projects, and developing staff. Collaborate with internal and external clients while staying updated on tax regul...

2 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$155K - $170K *

Lead the charge in architecting scalable Salesforce solutions, driving platform strategy, and ensuring high-quality integrations across KIPP's national ecosystem. Collaborate with stakeholders to deli...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.