Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$145K - $185K *

Transform the Cyber operations landscape by leading business development, shaping solutions, and executing contracts. Build trusted relationships, manage a diverse portfolio, and drive customer satisf...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $125K *

Shape the future of pharmacy operations by optimizing customer engagement and operational performance across a national portfolio. Drive proactive interventions and enhance workflow efficiency to ensu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $125K *

Elevate customer engagement by optimizing privacy program performance across a diverse portfolio. Ensure proactive intervention and support for healthcare privacy teams, driving compliance and enhanci...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $114K *

Transform the Value-Added Reseller ecosystem by leveraging channel expertise to drive growth, engaging partners, and developing robust strategies for customer acquisition and revenue expansion within...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$500K+*

Accelerate progress at driving new enterprise sales for AI platforms, owning the full sales cycle from prospecting to closing. Engage with CXOs across key industries to deliver measurable business out...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$145K - $185K *

Engage the customer lifecycle by developing scalable marketing programs that enhance onboarding, retention, and expansion. Collaborate cross-functionally to transform insights into impactful strategie...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Champion the growth of hematology products by educating healthcare providers, driving demand, and fostering relationships within cancer centers. Leverage cross-functional teams to ensure a positive ex...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $130K *

Analyze market trends and performance metrics to drive actionable insights across marketing, sales, and revenue operations. Collaborate with cross-functional teams to optimize strategies and enhance g...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$220K - $240K *

Lead the development of client data strategies and actuarial studies, ensuring accurate financial projections and effective communication with clients. Collaborate with teams to optimize health benefi...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $163K *

Join a dynamic Solutions Architecture team to tackle complex technology challenges, drive customer success, and enhance product offerings across diverse industries. Your expertise will shape outcomes...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Drive innovative technology solutions that enhance operational performance, ensuring secure and reliable infrastructure. Collaborate with cross-functional teams to lead projects, manage budgets, and a...

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$95K - $115K *

Shape the future of connectivity by optimizing and supporting complex LAN/WAN environments. Collaborate with teams to deliver secure, reliable network solutions that enhance business performance and m...

Pella, IARemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$88K - $105K *

Join a dynamic team to deploy and optimize complex LAN/WAN environments, ensuring secure and resilient network infrastructure while collaborating with internal customers to deliver effective technolog...

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$140K - $165K *

Shape the future of property accounting by leading a dynamic team, ensuring timely financial reporting, and driving innovative processes that enhance client trust and operational efficiency across mul...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$95K - $115K *

Empower customer retention and advocacy by leading US-focused programs. Collaborate cross-functionally to enhance customer journeys, ensuring clear communication and value delivery while optimizing en...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$179K - $243K *

Lead the charge in driving growth for an OCIO investment solutions business by developing institutional relationships and winning complex mandates across diverse markets. Collaborate with key stakehol...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $150K *

Accelerate customer journey operations by driving scalable processes and systems. Collaborate cross-functionally to enhance customer success, technical support, and partner engagement, ensuring effici...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$190K - $220K *

Engage with key stakeholders as a Senior Medical Science Liaison, driving prelaunch and launch strategies. Build trusted relationships, deliver scientific insights, and influence adoption in a dynamic...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Transform your career by owning complex software features that integrate virtual machines into a secure platform. Collaborate across teams to deliver innovative solutions while establishing strong eng...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$165K - $231K *

Transform complex security challenges into innovative solutions for public-sector and commercial clients. Lead technical pre-sales efforts, collaborating with sales teams to deliver tailored architect...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $185K *

Unlock your potential by leading a dynamic team to drive channel partnerships, transforming opportunities into revenue-generating relationships across diverse verticals in a fast-growing ecosystem...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$165K - $195K *

Engage in strategic solution development for Federal Government initiatives, translating client needs into innovative technical strategies. Collaborate with cross-functional teams to deliver compellin...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$76K - $122K *

Join a team that's dedicated to providing expert consulting on accounting methods. You'll manage diverse client projects, conduct technical research, and develop training materials, all while working...

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$105K - $132K *

Join a team that's dedicated to optimizing employee benefits programs. You'll manage US benefits operations, enhance vendor performance, and shape global strategies, ensuring a seamless, employee-cent...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Join a team that's dedicated to advancing hematology care by educating healthcare providers and driving demand for innovative therapies. Leverage your expertise to foster relationships and ensure a po...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.