Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$120K - $150K *

Unlock potential by driving AI deployment strategies with clients, translating business needs into actionable use cases, and ensuring successful model adoption. Collaborate closely with engineers and...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$87K - $230K *

Drive your career forward by leading service delivery operations, optimizing performance, and enhancing client relationships. Collaborate with teams to ensure effective project execution and continuou...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$100K - $160K *

Lead the charge in advancing next-gen GPS and PNT systems through architecture, requirements development, and project management, ensuring compliance and collaboration across engineering teams for mis...

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$116K - $150K *

Drive innovative SAP Finance solutions by leading consulting projects, shaping proposals, and guiding teams to deliver value for clients in the Financial Services sector. Leverage extensive experience...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$140K - $160K *

Shape the future of demand generation by driving impactful campaigns, collaborating with cross-functional teams, and leveraging AI to enhance marketing efficiency. This role offers a chance to innovat...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Transform clinical quality by supporting training initiatives, monitoring clinician performance, and ensuring compliance with quality standards for successful operational processes and clinician suppo...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$117K - $143K *

Empower small businesses by developing AI solutions that streamline workflows. Collaborate closely with customers to identify challenges and create impactful software that enhances efficiency and driv...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$155K - $160K *

Shape the future of data solutions by designing scalable architectures that drive AI and analytics initiatives. Collaborate with cross-functional teams to implement innovative strategies that enhance...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $190K *

Accelerate progress at a leading Customer Success team, driving renewal outcomes and enhancing team effectiveness through innovative engagement strategies and AI-driven solutions for a diverse portfol...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$164K - $245K *

Transform vendor legal operations by leading negotiations and enhancing processes. Collaborate with cross-functional teams to streamline agreements and empower stakeholders, ensuring efficiency and sc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Transform project execution by serving as the key liaison among clients, contractors, and design teams on diverse drinking water and wastewater projects, ensuring effective communication and adherence...

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$118K - $147K *

Join our dynamic MEP/FP team to lead plumbing design for diverse projects, ensuring high-quality deliverables and technical consistency while mentoring engineers and coordinating with multidisciplinar...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$150K - $200K *

Empower our growth by managing the positioning, messaging, and GTM strategy across multiple industries, ensuring impactful narratives that resonate with diverse stakeholders and drive revenue growth t...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $200K *

Drive your career by owning the go-to-market strategy for our AI Agent platform. Collaborate with cross-functional teams to create compelling narratives and enable sales, while launching innovative pr...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Lead strategic sales initiatives across diverse sectors, driving growth by cultivating relationships and delivering tailored solutions. Manage a territory, engage with partners, and achieve sales goal...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Advance sales growth by developing key relationships in the solar industry. Drive strategic initiatives across the Eastern U.S. while managing complex sales processes and collaborating with internal t...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$210K - $250K *

Elevate your career by driving revenue growth and strategic partnerships within a leading Oracle practice. Lead cross-functional teams to enhance client success and market positioning while fostering...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$210K - $250K *

Shape the future of patient access by leading integrated strategies that enhance customer engagement and optimize portfolio performance across diverse healthcare channels, driving sustainable growth a...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$90K - $152K *

Advance your career by leading mainframe capacity planning initiatives, optimizing performance, and driving automation solutions. Collaborate with teams to enhance operational efficiency and mentor ju...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Shape the future of engineering by delivering innovative solutions and managing complex projects. Collaborate with teams to enhance technical expertise while mentoring junior engineers and ensuring co...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$106K - $284K *

Join a team that’s redefining pharmacy and healthcare through innovative digital solutions. As a Staff Software Development Engineer, you'll lead in creating next-generation platforms, ensuring qualit...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$119K - $145K *

Advance supply chain efficiency by optimizing operations, collaborating cross-functionally, and implementing innovative solutions. Engage with stakeholders to analyze performance metrics and support k...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Drive the development of innovative security systems using AI/ML, managing risk across identity and access management. Collaborate with cross-functional teams to enhance security while maintaining ope...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $110K *

Champion the management of complex liability claims, ensuring thorough investigations, negotiations, and settlements. Collaborate with internal and external stakeholders to maintain high standards of...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Transform enterprise AI initiatives by leading technical pursuits, architecting scalable solutions, and driving impactful client engagements. Collaborate across teams to ensure successful delivery and...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.