Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$80K - $95K *

Optimize patient safety practices across healthcare operations by assessing, planning, and implementing quality improvement initiatives. Collaborate with leadership to drive transformational change an...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Drive transformational change by assessing and enhancing patient safety practices. Collaborate across teams to implement quality operations, leveraging data-driven decisions to ensure effective health...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$72K - $110K *

Lead the charge in managing a diverse portfolio of network organizations, fostering relationships, and implementing strategic capacity-building initiatives to enhance organizational performance and su...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Champion the delivery of civil works and architectural projects, overseeing contractors and ensuring high-quality execution from site prep to completion. Leverage your expertise to manage complex site...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $128K *

Analyze and monitor security alerts, investigate threats, and enhance SOC processes. Collaborate with teams to ensure cybersecurity measures are effective, while documenting incidents and providing te...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$75K - $142K *

Lead a team of specialists in managing absence and claim cases, ensuring operational excellence and high-quality service delivery while fostering a supportive and growth-oriented environment for team...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Unlock potential by leading our marketplace operations, connecting first responders with experienced coaches. Drive efficiency, manage cross-functional teams, and ensure seamless service delivery whil...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$123K - $157K *

Advance your career by leading strategic sourcing for metals, driving cost savings and supplier performance. Engage with cross-functional teams to influence decisions and ensure supply continuity whil...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$123K - $157K *

Lead the charge in global sourcing strategies for plastics, driving supplier relationships and cost optimization while ensuring supply continuity and supporting new product introductions across manufa...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$184K - $254K *

Shape the future of Procurement by leading enterprise capabilities that enhance performance, streamline processes, and drive technology integration, ensuring measurable value and strategic alignment a...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$184K - $254K *

Shape the future of corporate strategy by leading cross-functional teams to develop enterprise-wide strategic plans, drive growth initiatives, and influence senior leadership decisions through data-dr...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$138K - $191K *

Join a team that's redefining healthcare innovation by translating ideas into impactful solutions. Collaborate with senior executives to drive strategic initiatives and enhance population health throu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$129K - $177K *

Champion the development of intelligent decision systems using machine learning and reinforcement learning to enhance personalized healthcare recommendations, driving impactful outcomes for millions o...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$104K - $143K *

Empower healthcare transformation by developing strategic initiatives that enhance operational efficiency and clinician productivity. Collaborate cross-functionally to drive impactful solutions and im...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in developing and executing business strategies to acquire new clients, expand market reach, and drive sustainable revenue growth through consultative selling and strategic relationshi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$106K - $175K *

Lead the charge in managing a diverse portfolio of agribusiness accounts, driving profitability and growth through strategic underwriting and relationship-building with agents and brokers in a dynamic...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$87K - $151K *

Unlock potential by providing expert remote clinical applications support for advanced molecular imaging. Leverage your clinical knowledge and customer service skills to enhance productivity and deliv...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Reimagine your career by joining a dynamic team focused on optimizing Artificial Lift systems. You'll lead technical installations, enhance well productivity, and ensure adherence to safety standards...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$81K - $165K *

Unlock potential by managing the financial integrity of a high-impact loyalty program. Ensure compliance, accuracy, and timely reporting while collaborating with cross-functional teams to drive growth...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$90K - $100K *

Champion influencer marketing strategies that drive brand growth, manage client relationships, and execute impactful campaigns. Collaborate cross-functionally to analyze performance and innovate appro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$96K - $144K *

Take ownership of branch operations, driving performance across engineering, testing, and drilling divisions while fostering a collaborative environment and ensuring client satisfaction and financial...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Drive compliance excellence by leading insurance operations, optimizing processes, and mitigating risks across a commercial loan servicing portfolio while ensuring adherence to regulatory and investor...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $100K *

Unlock potential by joining a dynamic team as a Workday Benefits Consultant, where you'll drive client success through innovative solutions, manage multiple projects, and provide expert guidance in th...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$88K - $105K *

Lead the charge in implementing risk and fraud management solutions, collaborating with clients and cross-functional teams to ensure successful project delivery and integration within Azure environmen...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $100K *

Join a team that's dedicated to providing exceptional technical support for enterprise software applications. Collaborate with customers and development teams to troubleshoot issues, enhance software...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.