Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,016

Sort By: Relevance

$80K - $95K *

Lead transformative initiatives as a Traveling Facility Administrator, driving operational excellence and financial performance across diverse locations. Collaborate with cross-functional teams to enh...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in managing complex clinical trials, ensuring timely delivery, budget adherence, and high-quality outcomes while collaborating with multidisciplinary teams and stakeholders to enhance...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive compliance and contract administration for federal government contracts. Collaborate with cross-functional teams to ensure adherence to regulations, manage audits, and maintain records. Shape pr...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $150K *

Lead the charge in building long-term customer relationships while optimizing operations. As a Business Manager, you'll drive strategic growth, manage key accounts, and collaborate across teams to enh...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Transform product operations by enhancing collaboration across teams and streamlining the launch processes. Utilize data-driven insights and AI to identify bottlenecks and drive efficiency, ensuring s...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$80K - $95K *

Reimagine operational efficiency by overseeing plant management, leading personnel, and driving production goals while ensuring safety and quality standards are upheld throughout manufacturing process...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$106K - $176K *

Join a team that's transforming healthcare finance by leading patient financial services operations. Drive revenue cycle improvements, manage billing processes, and enhance compliance while fostering...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Business Services

$110K - $125K *

Engage with a dynamic team to oversee copy responsibilities, crafting compelling content across various mediums. Collaborate creatively to drive engagement for diverse audiences, including healthcare...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Empower your career by joining a dynamic team as a Field Support Engineer, where you'll tackle complex technical challenges in mission-critical environments, leveraging your expertise in Red Hat OpenS...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Elevate your career by contributing to critical security initiatives, leveraging your expertise in incident response, cryptographic modernization, and technical policy formulation to enhance enterpris...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$175K *

Engage with high-net-worth clients, converting prospects to loyal partners. Leverage provided leads and support to educate about wealth management solutions while developing your sales expertise in a...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$83K - $104K *

Join a team that's driving strategic marketing initiatives and influencing success. Collaborate with leaders to develop compelling narratives and innovative strategies that elevate project pursuits an...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$132K - $338K *

Lead the charge in defining AI-native architecture methodologies, owning technical assets and delivering enterprise-scale transformations while collaborating with sales leadership on high-stakes engag...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$94K - $293K *

Discover innovative data solutions by leading migration engagements, focusing on AI systems. Utilize advanced techniques for data lineage and evidence extraction to ensure robust data pipelines and pr...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$112K - $338K *

Champion the design and delivery of transformative CIAM solutions, enhancing customer engagement and security across digital channels while leading multi-disciplinary teams and managing executive rela...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$132K - $302K *

Lead the charge in transforming infrastructure landscapes to optimize performance, drive digital innovation, and deliver measurable business outcomes while advising C-suite executives and fostering hi...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Business Services

$100K - $110K *

Drive valuable insights by enhancing Anaplan models and dashboards, collaborating with teams to implement solutions and improve functionality, while supporting users throughout the development lifecyc...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$173K - $234K *

Engage in transformative sales strategies to enhance Amgen's Oncology portfolio. Build strong relationships with key accounts, drive strategic initiatives, and optimize business performance across div...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$173K - $234K *

Drive strategic account management for oncology, fostering relationships with key healthcare providers to enhance portfolio performance and patient care initiatives across multiple states...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Empower operational excellence by overseeing daily commissioning activities, ensuring compliance with global standards, and driving safety in a dynamic environment focused on data center functionality...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$385K - $400K *

Transform regional sales performance by leading a high-impact team, driving strategic growth, and utilizing best practices to meet ambitious quotas within a dynamic environment. Foster relationships a...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$212K - $287K *

Transform the Hematology landscape by leading a high-performing sales team, driving strategic initiatives, and ensuring compliance while exceeding sales objectives in the Great Plains region...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$184K - $356K *

Drive technical engagement with telecom accounts, connecting customer workloads to NVIDIA's ecosystem. Serve as a trusted advisor, co-design scalable architectures, and lead technical enablement to en...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$145K - $170K *

Join us to drive strategic sales initiatives, leveraging a robust resource model and tech stack to achieve performance goals and maximize customer value in a dynamic, collaborative environment...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $90K *

Transform the claims landscape by managing commercial property claims, collaborating with diverse teams, and enhancing your expertise in global and excess lines. Join a dynamic environment focused on...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.