Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$93K - $146K *

Champion sustainable design by leading complex mechanical systems for high-performance buildings, ensuring compliance with advanced standards and certifications while driving innovative engineering so...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$124K - $197K *

Drive excellence by overseeing 340b pharmacy services in a community health center, ensuring quality care for diverse patient populations while managing a dedicated team and optimizing pharmacy operat...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in managing district field service operations, driving profitability, and enhancing customer satisfaction through effective team leadership and strategic coordination across multiple r...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $219K *

Optimize medical sponsorship strategies and operations by collaborating with stakeholders, managing budgets, and ensuring timely execution of congress activities while enhancing process efficiency and...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $167K *

Drive end-to-end service delivery and operational excellence across multi-tower infrastructure environments. Lead global teams, manage financials, and ensure compliance while fostering continuous impr...

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $150K *

Drive global access strategies for an innovative rare disease treatment, collaborating across teams to enhance payer insights and develop impactful materials. Lead initiatives that shape market entry...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$96K - $125K *

Join a team that's focused on enhancing delivery across cross-functional initiatives, ensuring timely execution and risk management. Collaborate with diverse teams to drive improvements and elevate cu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$207K - $250K *

Unlock your potential as you lead engineering teams in building innovative platforms and AI experiences. Collaborate across departments to drive technical direction and elevate team performance while...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$100K - $120K *

Drive growth by leading a high-performing sales team focused on early-stage companies. Collaborate with leadership to refine strategies, enhance sales processes, and foster a supportive culture, ensur...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Join a team that's dedicated to ensuring compliance and excellence in clinical trials. Collaborate with cross-functional teams and site personnel to manage monitoring activities, uphold regulatory sta...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Join a team that's redefining cybersecurity by leveraging AI to enhance defense strategies. Engage with customers across the Americas, translating complex concepts into actionable insights while drivi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by driving growth for a leading payment solution, collaborating with cross-functional teams to enhance customer engagement and conversion. This role demands agility in a fast-paced en...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Transform business development by leveraging technical expertise to build customer relationships, identify opportunities, and deliver tailored solutions. Join a dynamic team focused on driving sales g...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$120K - $140K *

Transform the renewable energy landscape by driving solar module sales in the Northwest. Leverage your expertise to build relationships, uncover opportunities, and achieve sales targets while managing...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$138K - $165K *

Shape the future of consumer applications by leading machine learning and Generative AI initiatives. Build robust data pipelines, develop and deploy models, and drive business impact through experimen...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Partner with us to tackle complex operational challenges, driving impactful initiatives across our portfolio. This role offers hands-on experience and growth opportunities, ideal for future leaders ea...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $105K *

Engage with global customers as a trusted advisor, solving complex workflow challenges through innovative color management solutions and professional services, while collaborating with sales teams to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$66K - $102K *

Unlock your potential as a Senior SAP FICO Consultant, driving impactful solutions and collaborating with teams to enhance financial processes. Leverage your expertise to deliver value in a dynamic co...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Deliver expert pharmacy services, ensuring patient safety and medication management while mentoring team members. Collaborate with healthcare professionals to provide compassionate care and drive oper...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $104K *

Optimize ETL processes by designing and maintaining robust data integration solutions. Collaborate with cross-functional teams to ensure data accuracy and performance, while mentoring junior developer...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$150K - $220K *

Unlock potential by leading agent acquisition efforts to drive growth, enhance sales processes, and optimize recruitment strategies. Collaborate with teams to build a high-performing sales organizatio...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$110K - $130K *

Join a dynamic team to provide expert pharmacy services, educate patients, and ensure medication safety. Lead clinical healthcare initiatives while mentoring staff in a collaborative environment focus...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Elevate patient care by providing expert pharmacy services, mentoring team members, and ensuring medication safety. Drive clinical healthcare initiatives while navigating challenges in a collaborative...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$160K - $170K *

Elevate data engineering excellence by designing and implementing complex data solutions, mentoring engineers, and collaborating across teams to drive impactful data initiatives and architectural inno...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Advance compliance operations by conducting transaction monitoring, investigating suspicious activities, and collaborating cross-functionally to ensure regulatory adherence in a dynamic digital asset...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.