Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Average Salary: $110,033
$230K - $368K *
Shape the future of high-scale SaaS solutions by leading architectural design, guiding teams, and driving impactful software strategies in a collaborative environment that values innovation and mentor...
Reposted 1 week ago
Therapy Development Specialist, Phoenix, AZ or Las Vegas, NV
$100K - $150K *
Collaborate with healthcare professionals to enhance therapy awareness and optimize care pathways for patients with venous thromboembolism. Drive education and program development initiatives across a...
1 week ago
Director, Strategic Account Development - Lockheed Martin
$150K - $180K *
Lead the charge in driving new business for the Aerospace & Defense sector, collaborating with cross-functional teams to capture high-value opportunities and establish executive relationships, ensurin...
1 week ago
$81K - $122K *
Contribute to financial analysis and reporting, supporting strategic decision-making across departments. Collaborate with stakeholders to enhance budgeting, forecasting, and data management processes...
1 week ago
Performance Marketing & Marketing Operations Manager (United States)
$95K - $115K *
Drive paid media performance and optimize marketing operations to enhance growth. Manage campaign execution, budget allocation, and HubSpot systems, ensuring effective lead generation and data-driven...
1 week ago
Associate Director or Director, Clinical Outsourcing
$175K - $250K *
Lead the charge in executing clinical outsourcing strategies across oncology trials, managing vendor relationships, contract negotiations, and financial oversight to ensure optimal performance and com...
Reposted 1 week ago
$120K - $145K *
Champion quality by designing and leading automated testing strategies for diverse products. Collaborate with engineers to enhance test frameworks, mentor teams, and ensure high standards across platf...
1 week ago
Regional Congress Account Manager
$75K - $110K *
Transform client engagement in a dynamic, detail-oriented environment. Collaborate with cross-functional teams to ensure program success and elevate customer experiences in the Life Sciences sector. D...
1 week ago
$145K *
Drive significant growth by managing the entire sales cycle for mid-market nonprofit clients, nurturing relationships to unlock their potential and optimize the use of our innovative solutions, while...
Reposted 1 week ago
$100K - $120K *
Lead the charge in developing client relationships and driving new business opportunities in the Life Sciences sector. Utilize a consultative sales approach to create bespoke marketing campaigns and m...
1 week ago
$90K - $115K *
Unlock potential by leveraging your pharmacy expertise to drive client growth and retention. Collaborate with teams to provide consultative support and insights in pharmacy and medical policy, enhanci...
1 week ago
Director, Franchise Operations - Total Portfolio, NorCal MU
$145K - $169K *
Transform the Coca-Cola business by managing bottler partnerships, driving strategic planning, and ensuring operational excellence. Lead initiatives that enhance franchise capabilities and foster sust...
1 week ago
Account Executive - In-Territory (San Diego, CA)
$91K - $110K *
The Account Executive in San Diego is responsible for managing the full sales cycle, including prospecting, building relationships, and closing deals. This role requires a proactive approach to expand...
Reposted 1 week ago
Nuclear Simulator Software Engineering Analyst Senior
$95K - $115K *
Unlock your potential as a technical owner, ensuring the reliability and performance of nuclear simulator systems. Collaborate across teams to enhance operator training and compliance in a dynamic, sa...
1 week ago
$100K - $120K *
Shape the future of our Bike category by driving merchandising strategy, managing vendor relationships, and mentoring a dynamic team. Own the budget and make impactful decisions to enhance financial p...
1 week ago
Group Director, Consumer Services
$150K - $180K *
Join a dynamic team as a senior leader, driving client relationships and revenue growth in lead-generation sectors. You'll manage a diverse portfolio, ensuring lead quality and speed while leveraging...
Reposted 1 week ago
$110K - $130K *
Champion the development of AI-driven products, leading strategic initiatives and execution. Drive product roadmaps, manage budgets, and ensure alignment with business goals while delivering impactful...
1 week ago
$105K - $245K *
Lead the charge in developing and empowering a high-performing sales team. Foster a strong team culture while driving improvement and accountability in a rapidly changing environment, leveraging data...
Reposted 1 week ago
Senior Director, Client Sales & Insights
$100K - $130K *
Drive commercial activation and revenue growth for a multi-million-dollar portfolio, leveraging strategic insights and AI to enhance client engagement and decision-making. Lead cross-functional teams...
1 week ago
Senior QA Automation Engineer - SDET
$100K - $120K *
Drive quality assurance as a Senior QA Automation Engineer, enhancing our distributed database platform through designing automated tests, validating features, and improving release processes while wo...
Reposted 1 week ago
Data Architect [ Must Have EPIC Caboodle $ Population Health ]
$110K - $130K *
Engineer innovative data solutions to optimize population health, enhance quality care analytics and reporting, while ensuring data governance and compliance within the healthcare domain. Collaborate...
Reposted 1 week ago
$62K - $103K *
Drive open-source research and analysis to support high-profile government clients. Conduct media monitoring, identify trends, and prepare concise reports to inform decision-making, all while working...
Reposted 1 week ago
Mid Market Account Executive, Toast Retail
$98K - $157K *
Join us to source and close multi-location retail deals, building a new sales strategy for complex accounts. You'll navigate buyer dynamics, drive value-based selling, and collaborate with cross-funct...
Reposted 1 week ago
Inpatient Coding Specialist II (Remote)
$137K - $154K *
Advance the future of healthcare coding by accurately assigning ICD-10 codes and MS-DRGs for inpatient records. Collaborate with clinical teams to ensure compliance and optimize reimbursement while ma...
1 week ago
Director / Senior Director / Executive Director, Regulatory Affairs
$210K - $275K *
Transform regulatory affairs in oncology by leading strategic submission initiatives and cross-functional collaborations, ensuring compliance and quality for impactful development programs. Drive regu...
Reposted 1 week ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.