Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$94K - $122K *

Empower operational excellence by providing technical support for production systems. Lead complex projects as a subject matter expert, enhancing system performance and driving process improvements th...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$65K - $105K *

Lead the charge in developing and managing technical documentation for a NATO SATCOM modernization program, ensuring accuracy and compliance throughout the system lifecycle while collaborating with mu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$175K - $292K *

Lead the charge in driving demand and revenue growth through innovative marketing strategies, integrated campaigns, and collaboration with cross-functional teams to enhance buyer journeys and optimize...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$80K - $130K *

Transform user engagement by leading seasonal campaigns and communications, ensuring tailored messaging for diverse audiences. Drive insights through experimentation and collaboration to enhance digit...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $200K *

Join a team that's driving revenue growth through strategic outbound prospecting and new business development. You'll own the full sales cycle, engaging key decision-makers and turning prospects into...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Elevate commercial performance by partnering with teams to translate strategies into actionable enablement. Drive measurable outcomes through effective training, tools, and continuous improvement acro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Elevate quality management systems as you lead GxP processes, ensuring compliance and readiness for commercialization. Collaborate across functions to drive quality initiatives and support pivotal reg...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$104K - $120K *

Drive strategic real estate initiatives and manage complex projects to enhance portfolio performance and operational scalability. Collaborate across functions to influence decisions and ensure success...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Lead the review and evaluation of medication prior authorization requests, ensuring safe and cost-effective therapy while adhering to clinical guidelines and regulatory standards. Collaborate with cli...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Unlock potential by leading client teams to drive retention and growth. Collaborate cross-functionally to shape strategic market positioning and nurture executive relationships, all while cultivating...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Elevate patient care by filling prescriptions, counseling customers, and supporting pharmacy operations. Collaborate with a dedicated team to enhance community wellness through outreach and education...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$153K - $199K *

Join a team that's dedicated to optimizing access and reimbursement for HIV prevention therapies across complex health systems. This role requires strategic relationship management and extensive trave...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $160K *

Join a team that's dedicated to managing complex general liability claims, focusing on Construction and specialty lines. Drive strategic claim resolutions, ensure compliance, and enhance customer sati...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$110K - $130K *

Transform organizational change by leading client engagements, developing tailored OCM plans, and ensuring user adoption with minimal disruption. Collaborate with stakeholders to drive successful chan...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$50K - $120K *

Grow your career with a dynamic role in automotive sales, where you'll engage customers, showcase vehicles, and build lasting relationships. Enjoy comprehensive training and support as you achieve you...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$150K - $180K *

Empower innovation by architecting next-gen AI-driven CRM solutions. Lead a dynamic team to optimize data processing, enhance automation, and deliver exceptional user experiences while driving market...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$145K - $160K *

Empower healthcare leaders by delivering actionable insights through advanced analytics. Collaborate with executives to address strategic workforce challenges, utilizing AI-driven data solutions to en...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$80K - $95K *

Champion a culture of safety by managing and implementing field safety programs for construction projects, ensuring compliance with regulations and fostering a proactive safety environment across dive...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$88K - $105K *

Champion innovative solutions by evaluating customer needs and delivering technical expertise. Collaborate with teams to manage complex projects, ensuring effective application solutions and driving r...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$78K - $111K *

Join us to design and implement innovative ServiceNow solutions, enhancing business operations through automation and integration. Collaborate with stakeholders to deliver effective ITSM and ITOM appl...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$246K - $339K *

Champion the evolution of our Data Platform by architecting scalable solutions for large-scale data migrations, empowering teams with self-service storage capabilities, and ensuring reliability across...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$120K - $180K *

Optimize sourcing strategies for electronic components, fostering supplier partnerships and ensuring reliable access to critical materials. Collaborate across teams to enhance procurement processes an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$94K - $266K *

Lead the charge in delivering high-quality proposal content for GCC opportunities across the Americas. Collaborate with teams to ensure timely submissions and strengthen responses using GCC domain kno...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$193K - $309K *

Pioneer innovative developer experiences by setting technical direction and enhancing workflows. Collaborate across teams to design solutions that empower engineers, leveraging AI to redefine software...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$128K - $205K *

Elevate your career by owning the TA tech stack, driving integrations, and enhancing system efficiency. Collaborate with cross-functional teams to optimize processes and lead vendor relationships, all...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.