Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$110K - $140K *

Transform public safety by leading sales for drone technology in mid-sized agencies. Own your territory, drive full-cycle deals, and build trust with key stakeholders to secure funding and deployment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$225K - $265K *

Unlock your potential as a technical leader, driving innovative solutions in Web Application Firewall integration. Collaborate across teams to enhance security and deliver impactful customer outcomes...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$81K - $138K *

Explore a dynamic role where you'll lead commercial banking solutions, translating client needs into actionable designs while ensuring compliance and best practices. Collaborate with stakeholders to d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $105K *

Elevate project quality and commissioning for hyperscale data centers. Lead cross-functional teams to ensure timely delivery, compliance with specifications, and effective communication with stakehold...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Lead transformative process improvements in financial services construction projects. Collaborate with stakeholders to enhance operational efficiency, optimize workflows, and drive sustainable outcome...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$138K - $243K *

Champion AI integration across business functions, driving innovation and efficiency. Collaborate with leaders to identify opportunities, develop strategies, and ensure alignment with business goals f...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$300K *

Lead the charge in developing strategic technology partnerships that enhance product integrations. Collaborate with cross-functional teams to identify opportunities, design solutions, and drive succes...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$122K - $183K *

Elevate user growth and monetization through thoughtful design and experimentation, collaborating closely with cross-functional teams to enhance onboarding and product engagement while maintaining hig...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Lead and develop a high-performing video editing team, ensuring quality and timely delivery of compelling performance ads. Engage in hands-on editing while driving creative strategy and leveraging per...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$85K - $116K *

Transform network operations by providing real-time support and monitoring for a complex communications infrastructure, ensuring reliability and security while collaborating with engineering and field...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$63K - $156K *

Deliver impactful legal representation in health and human services, advocating for vulnerable populations. Engage in complex Medicaid matters, ensuring compliance with state and federal laws while fo...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$199K - $235K *

Elevate your career as you design and maintain backend services that manage customer entitlements and usage workflows. Collaborate with cross-functional teams to ensure data integrity and deliver impa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$115K *

Create impactful enablement resources for pharmacy products, driving commercialization and sales success. Collaborate cross-functionally to enhance customer engagement and operational efficiency, ensu...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K *

Join a team that's driving growth by onboarding and activating merchants in the home services sector. This role involves managing the sales process, collaborating cross-functionally, and maintaining a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Transform client challenges into innovative AI solutions. Collaborate with teams to design, build, and deploy production-quality software, ensuring reliable AI applications that deliver measurable imp...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$175K - $215K *

Elevate product innovation by leading cross-functional teams to develop AI-driven solutions that enhance user experience and drive business success. Collaborate closely with engineering and marketing...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $130K *

Innovate the go-to-market systems by building AI agents and infrastructure that drive pipeline efficiency, ensuring seamless integration and reliability across sales and marketing operations...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

$85K - $93K *

Join a team that's dedicated to executing risk-based audits, ensuring compliance, and enhancing program integrity through thorough analysis and collaboration across departments. Drive improvements whi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$70K - $105K *

Optimize provisioning strategies for mission-critical SATCOM systems. Collaborate with cross-functional teams to ensure operational readiness and minimize downtime through effective logistics support...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$160K - $190K *

Lead the legal strategy for a fast-growing stablecoin business, negotiating complex agreements and advising on commercial issues. Collaborate with cross-functional teams to scale products and enhance...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$104K - $135K *

Lead a dynamic UX/UI design initiative, optimizing workflows and enhancing user experiences through research and collaboration. Drive impactful design solutions while mentoring the team and leveraging...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$220K - $240K *

Elevate your career by leading product innovation in restaurant technology. Drive impactful solutions, enhance user experiences, and collaborate closely with restaurant teams to scale our in-store off...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$85K - $95K *

Join a team that's redefining clinical recruitment by leading full-cycle hiring for Registered Dietitians. Drive innovative sourcing strategies and ensure a seamless candidate experience in a fast-pac...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$162K - $243K *

Lead a dynamic team in managing complex clinical research trials, ensuring strategic execution and client satisfaction. Drive project success through effective communication, budget oversight, and qua...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$147K - $220K *

Optimize project delivery by leading clinical study initiatives, ensuring quality, budget, and timelines are met. Collaborate with teams and clients to drive success in complex global trials while man...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.