Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$130K - $155K *

Unlock potential by driving innovative AI solutions through hands-on engineering and client collaboration. Transform complex business challenges into reliable, production-ready software while enhancin...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Elevate your career by leading strategic initiatives to enhance U.S. swine health. Collaborate with industry stakeholders to drive research, disease preparedness, and impactful programs that support t...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$118K - $147K *

Drive successful project delivery by implementing cutting-edge AI/ML solutions on Google Cloud. Collaborate with cross-functional teams to develop strategies, conduct client discovery, and provide tec...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$206K - $267K *

Optimize technology investments by providing visionary architecture leadership, aligning enterprise capabilities with corporate goals, and driving strategic initiatives to enhance operational efficien...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Transportation

$100K - $135K *

Join us to evaluate and underwrite specialty insurance risks, fostering broker relationships and ensuring profitability while maintaining high standards of customer service and operational efficiency...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$132K - $167K *

Lead the charge in strategic talent acquisition for Commercial roles, managing complex searches and guiding senior leaders through the hiring process while leveraging data and innovative tools to enha...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $240K *

Empower your career by driving technology partnerships, managing relationships, and developing go-to-market strategies. Collaborate with cross-functional teams to enhance integration and achieve mutua...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $230K *

Unlock potential by driving new business in the Insurance sector with your sales expertise. Collaborate across teams to develop solutions that address client needs and position the firm as a leader, w...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Information Technology

$150K - $180K *

Champion global EHS initiatives by developing policies, leading compliance, and fostering a proactive safety culture across diverse operations, ensuring continuous improvement and risk management in a...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$80K - $110K *

Transform clinical data into engaging scientific content with growth opportunities. Collaborate, communicate, and adhere to guidelines in a dynamic environment, supporting varied projects across forma...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform project execution by leading complex construction initiatives, fostering client relationships, and mentoring future leaders. Drive financial performance and operational excellence while ensu...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Champion customer success within SLED organizations. Drive revenue growth by managing relationships, negotiating contracts, and delivering strategic value for an established client base in the public...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$166K - $200K *

Champion high-quality, person-centered care for seniors in skilled nursing facilities. Collaborate with teams to enhance patient outcomes, mentor staff, and drive clinical excellence while enjoying au...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $105K *

Grow your career with a transformative digital marketing role focused on optimizing web performance, driving SEO and CRO strategies, and leveraging AI for data insights to enhance user engagement and...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$125K - $160K *

Take ownership of strategic client relationships, driving retention and growth while leading negotiations and fostering executive partnerships. Collaborate cross-functionally to deliver exceptional cl...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$77K - $108K *

Transform financial operations by leading the Accounts Payable division. Oversee daily tasks, ensure compliance, manage staff, and maintain accurate records. Drive efficiency and accuracy in payment p...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $96K *

Innovate with us to lead complex, multi-phase projects, ensuring timely delivery and quality standards. Collaborate with cross-functional teams and external partners to drive project success while man...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$146K - $293K *

Drive enterprise sales in Aerospace & Defense, creating strategic opportunities and engaging C-suite executives. Own the full sales cycle, leveraging Siemens' technology to deliver measurable business...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$91K - $121K *

Elevate the commercialization process across the product portfolio, enhancing efficiency and data integrity. Lead cross-functional collaboration, implement automation innovations, and drive strategic...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$70K - $95K *

Join a team that's shaping the future of AI in international development. Lead market research initiatives to identify opportunities, analyze trends, and provide strategic insights that drive business...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$207K - $244K *

Shape the financial data landscape by leading analytics initiatives, ensuring accurate, timely reporting and compliance. Collaborate with cross-functional teams to build scalable data pipelines and ma...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$171K - $236K *

Drive customer success by managing relationships, identifying upsell opportunities, and collaborating with teams to ensure long-term growth and satisfaction for existing clients, focusing on measurabl...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$135K - $200K *

Join us as a Senior Product Manager to shape the strategy and roadmap for a key product area, leveraging AI to drive innovation and enhance client value while collaborating with cross-functional teams...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Pioneer the delivery of impactful product features by guiding Agile teams, prioritizing stakeholder needs, and translating complex requirements into actionable user stories. Drive collaboration and co...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Drive financial strategy and execution for new business and client retention in the Higher Education Sector, optimizing revenue and profitability while collaborating with cross-functional teams to ens...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.