Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$98K - $141K *

Drive efficiency and reliability by leading a team of Controls Engineers to enhance regional plant technology and optimize machine processes, ensuring consistent implementation of industry standards a...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$107K - $204K *

Unlock potential by leading embedded software engineering initiatives, optimizing DevSecOps pipelines, and mentoring teams. Collaborate across departments to enhance automation and drive innovation in...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$152K - $190K *

Champion the future of physical operations by leveraging IoT data to drive business transformation for mid-sized clients. Navigate complex sales processes, engage multiple stakeholders, and educate cu...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $200K *

Engage advisors and drive growth in wealth management products across the Mid-Atlantic. Utilize consultative sales skills, market insight, and relationship management to enhance business outcomes, ens...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $125K *

Advance business growth by fostering relationships and crafting innovative strategies that drive revenue. Collaborate across teams to identify opportunities and enhance operational excellence while en...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$174K - $374K *

Manage clinical oversight and mentorship in a remote role, guiding enterprise-wide medical decisions, reviewing complex cases, and ensuring evidence-based coverage determinations while collaborating a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$132K - $234K *

Elevate your career by supporting complex software sales cycles through impactful product demonstrations and tailored solutions. Collaborate with clients and partners to drive pipeline conversion and...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$350K *

Engage with key enterprise clients to drive revenue growth through strategic, solution-based sales. Develop lasting relationships and navigate complex sales processes while championing company values...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$222K - $278K *

Reimagine enterprise sales by developing executive relationships and leading customer engagements. Drive revenue growth through strategic deal-making with a focus on customers while embodying core cul...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$149K - $298K *

Unlock potential by leading the U.S. CRM Field Health Economics & Reimbursement team to enhance patient access and drive therapy adoption through strategic reimbursement initiatives and stakeholder co...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$92K - $123K *

Elevate your career by leading a dynamic claims team, ensuring compliance and excellence in customer service. Drive performance through coaching, strategic oversight, and effective communication while...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$125K - $150K *

Lead the charge in comprehensive pharmacy oversight, ensuring optimal patient care and operational efficiency. Collaborate with healthcare teams to enhance pharmacy services and mentor staff while man...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $105K *

Grow your career with a pivotal role in client relationship management, enhancing membership retention and expanding strategic partnerships through exceptional service and sales expertise in a dynamic...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$96K - $181K *

Lead the transformation of enterprise technology by architecting scalable GCP solutions and guiding cross-functional teams in developing robust AI-driven applications. Drive innovation through hands-o...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$88K - $145K *

Join a dynamic team to investigate and manage complex property claims, ensuring thorough evaluations and customer satisfaction while working independently in the field. Leverage your expertise to ment...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$210K - $250K *

Lead global operations for a diverse specialty materials portfolio, driving excellence in safety, quality, and supply chain. Foster innovation and optimize production to ensure timely delivery and cos...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$83K - $107K *

Empower the future of organ transplantation by screening donor offers, coordinating clinical evaluations, and collaborating with diverse teams to enhance organ utilization and patient outcomes in a dy...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$83K - $107K *

Transform donor assessment processes by screening organ offers, coordinating with transplant teams, and ensuring compliance with OPTN policies to enhance organ utilization and patient outcomes...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$176K - $287K *

Develop and maintain strategic relationships with key opinion leaders while serving as a clinical resource for healthcare professionals. Drive evidence generation and support educational initiatives i...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$153K - $207K *

Lead impactful initiatives in healthcare fraud analysis, driving data-driven solutions and collaborating with cross-functional teams to enhance Medicaid and Medicare outcomes while presenting findings...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $150K *

Join a team that's redefining threat detection by developing high-fidelity SIEM rules and leveraging AI tools. Collaborate across the detection pipeline to enhance response capabilities and drive inno...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $150K *

Drive high-fidelity detection development by leveraging threat intelligence and AI tools. Collaborate across the detection pipeline to enhance triage efficiency and accelerate threat disruption in a d...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $88K *

Empower your creativity as you design impactful brand assets across various channels, ensuring visual consistency and engaging storytelling. Collaborate with marketing to elevate brand identity and dr...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Food & Beverages

$60K - $110K *

Manage and optimize store remodels and new projects across the US, ensuring timely delivery and quality standards. Collaborate with teams, supervise associates, and travel frequently to oversee projec...

1 week ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$100K - $231K *

Transform healthcare outcomes by leading a team of Clinical Program Consultants to analyze data, optimize clinical programs, and drive strategic initiatives that enhance customer health and reduce cos...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.