Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Average Salary: $110,033
Principal Architect - Data Centers
$125K - $200K *
Join a team that's redefining architectural excellence by leading global projects, driving business growth, and fostering client relationships while overseeing studio operations and strategic initiati...
1 week ago
Regional Partner Sales Executive
$110K - $130K *
Lead the charge in driving revenue through strategic partnerships, enhancing market reach, and delivering customer value across your designated region while managing complex sales cycles and fostering...
Reposted 1 week ago
$120K - $145K *
Accelerate progress at the forefront of digital transformation by leading strategic initiatives, ensuring effective governance, and driving organizational change across global teams to enhance program...
1 week ago
$112K - $135K *
Transform the billing and pricing landscape by driving platform strategy, enhancing user experiences, and collaborating across teams to deliver innovative solutions that meet customer needs and busine...
1 week ago
Mobile Calibration Project Manager
$100K - $135K *
Manage the transition and steady-state phases of Client-Based Laboratories, overseeing calibration processes, training staff, and ensuring quality standards across multiple sites while maintaining str...
1 week ago
$110K - $130K *
Transform patient safety operations by leading a dedicated team, ensuring compliance, and enhancing pharmacovigilance processes. Collaborate cross-functionally to deliver high-quality safety services...
Reposted 1 week ago
$125K - $150K *
Accelerate growth by shaping innovative marketing strategies for consumer products. Lead brand development, community engagement, and performance marketing initiatives to make blockchain accessible an...
Reposted 1 week ago
$107K - $199K *
Unlock potential by leading financial modeling and risk assessment for value-based care arrangements. Collaborate with teams to analyze vendor performance and drive strategic insights, ensuring contra...
1 week ago
Territory Sales Manager - Lincoln, NE; Omaha, NE; Des Moines, IA
$150K *
Champion sales growth by driving Heartflow's innovative technology in your region. Build relationships with key clinical stakeholders, expand account usage, and achieve sales goals while collaborating...
Reposted 1 week ago
Enterprise Account Executive - Warehouse Robotics (North America)
$150K *
Champion new business across North America by selling autonomous mobile robots. Own the sales process, develop complex relationships, and structure high-value agreements, while driving innovative stra...
Reposted 1 week ago
Senior AI / ML Engineer (LLMs)
$200K - $235K *
Transform AI/ML systems by leading end-to-end development of innovative solutions. Tackle complex challenges in medical synthesis and help define and deploy advanced features that enhance user experie...
Reposted 1 week ago
Senior Software Engineer, Biggy Engineering
$187K - $220K *
Unlock potential by designing and building AI-powered solutions to enhance enterprise IT operations, collaborating directly with customers and driving impactful product features across backend and aut...
Reposted 1 week ago
Talent Acquisition & Experience Partner
$105K - $115K *
Lead the charge in full-cycle recruiting and onboarding, enhancing employee experience through strategic partnerships and innovative practices. Collaborate with teams to attract top talent and ensure...
1 week ago
$72K - $107K *
Join our team to enforce laws, maintain public order, and provide emergency assistance. As a vital community member, you'll patrol, respond to calls, and ensure safety while developing your skills in...
1 week ago
$80K - $95K *
Elevate operational excellence by leading a customer-centric team, developing strategic plans, and fostering partnerships to achieve business goals while ensuring safety and service quality...
Reposted 1 week ago
Senior Software Engineer, Compute Platform
$186K - $218K *
Elevate operational excellence by engineering reliable Kubernetes solutions that streamline compute orchestration, enhance automation, and drive AI integration for a robust developer experience across...
Reposted 1 week ago
$80K - $95K *
Shape the future of digital products by driving key business outcomes through collaborative problem-solving and iterative software delivery. Your expertise will enhance customer satisfaction and marke...
Reposted 1 week ago
Business and Data Analyst [U.S. Citizenship Required, Public Trust Suitability]
$90K *
Shape the future of business analysis by connecting program needs with technical solutions. Leverage your Salesforce expertise to enhance workflows, gather requirements, and collaborate with stakehold...
Reposted 1 week ago
IHE Cybersecurity Compliance & Incident Response Specialist
$135K - $150K *
Lead the charge in enhancing cybersecurity compliance and incident response for higher education institutions. Collaborate with stakeholders to manage incidents, evaluate compliance, and strengthen pr...
1 week ago
Vice President of Information Technology and Security
$180K - $220K *
Strategize and oversee the development of a cohesive IT and cybersecurity strategy to support a high-growth B2B software organization, ensuring alignment with business goals and compliance standards w...
1 week ago
Senior Enterprise AI Account Executive - Deasy Labs
$120K - $175K *
Drive your career forward by leading new logo acquisition with AI/ML teams. Own the sales cycle, build consensus across stakeholders, and deliver accurate forecasting while connecting AI products to g...
Reposted 1 week ago
AVP, Casualty Underwriting Performance - E&S/Specialty and Commercial Lines
$154K - $290K *
Join a dynamic team to shape strategic casualty underwriting initiatives, driving performance and innovation across multiple business lines while cultivating a high-performing culture and aligning wit...
1 week ago
$80K - $95K *
Elevate guest experiences by ensuring a safe, comfortable environment. Lead maintenance programs, prioritize repairs, and collaborate with management to uphold property standards while delivering exce...
1 week ago
Manager, Professional Services Federal
$128K - $160K *
Drive operational excellence and customer satisfaction by managing services teams, optimizing project delivery, and enhancing client engagement strategies for government clients, ensuring alignment wi...
Reposted 1 week ago
$115K - $125K *
Transform cybersecurity by leading penetration tests, identifying vulnerabilities, and recommending solutions to enhance system security. Collaborate with teams to ensure compliance with NIST standard...
1 week ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.