Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$170K - $190K *

Drive the successful delivery of AI-enabled health IT projects by coordinating teams, managing schedules, and ensuring integration into clinical workflows. Collaborate with stakeholders to achieve mea...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $130K *

Lead multi-site project implementations, coordinating teams and maintaining schedules to ensure successful delivery across phases. Drive stakeholder engagement and validate readiness for deployment in...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $130K *

Lead the charge in optimizing acquisition strategies for Federal contracts, providing expert guidance on procurement processes, market research, and contract administration to ensure effective service...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $175K *

Join a team that's building innovative web applications from the ground up. Take ownership of production systems, enhance user experiences, and drive AI-driven features while ensuring compliance with...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$107K - $119K *

Advance the effectiveness of clinical audit teams by designing and delivering targeted training programs. Collaborate with experts to enhance workflows and improve audit productivity, ensuring high st...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$147K - $192K *

Champion innovative sales strategies in the healthcare payer sector, targeting C-level executives. Drive growth through effective territory management and strategic market analysis, ensuring alignment...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$91K - $118K *

Lead the development and enhancement of critical software applications, ensuring performance and stability while collaborating with cross-functional teams to deliver market-driven solutions and suppor...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$97K - $116K *

Lead the charge in quality assurance by evaluating clinical audits to ensure compliance and accuracy. Utilize your expertise to mentor staff and drive process improvements that elevate the standard of...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Join a team that's driving digital transformation by coordinating virtual health initiatives, optimizing processes, and enhancing project delivery to improve customer experience and outcomes across th...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$135K - $210K *

Lead the charge in solving complex carrier connectivity challenges in commercial insurance. Collaborate with cross-functional teams to streamline workflows and enhance product delivery, ensuring seaml...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Advance customer success by managing mid-market accounts, driving growth, and fostering relationships. Collaborate with internal teams to enhance client experiences and achieve revenue targets while n...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$145K - $175K *

Shape the future of software engineering by leading modernization efforts, solving complex technical challenges, and mentoring teams. Collaborate across product boundaries to enhance system architectu...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Optimize executive operations by partnering with leadership to enhance strategic execution, manage communications, and drive organizational priorities. Leverage technology and exceptional organization...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$210K - $250K *

Reimagine the future of healthcare supply chain architecture by leading modernization efforts, ensuring secure data exchange, and driving intelligent automation across systems. This role balances oper...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$85K - $97K *

Lead the charge in developing robust full-stack solutions, enhancing integrations, and ensuring secure coding practices. Collaborate in agile sprints to deliver high-quality software that meets VA sta...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $97K *

Drive your career with a dynamic role focused on full-stack development, integrating REST APIs, and enhancing legacy applications while ensuring secure coding practices and compliance with accessibili...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $97K *

Join a dynamic team as a Full Stack Developer, where you'll design, code, and deploy innovative solutions, ensuring high-quality software delivery through agile methodologies and secure coding practic...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $97K *

Drive innovation as a Full Stack Developer, crafting robust applications and integrations. Collaborate in agile sprints to enhance VA enterprise services while ensuring secure coding practices and mai...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $97K *

Develop and enhance full-stack applications, integrating REST APIs and ensuring secure coding practices. Collaborate in agile sprints to deliver high-quality software solutions while refactoring legac...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Unlock your potential as you manage complex claims, ensuring compliance and timely resolutions. Collaborate with teams, provide technical guidance, and drive performance in a fully remote role with tr...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Champion the transition of state and local governments to modern cloud solutions. Build strategic relationships, navigate complex procurement processes, and drive measurable value through innovative t...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$123K - $154K *

Lead the execution of strategic data and analytics initiatives, driving modernization and governance across enterprise platforms. Collaborate with cross-functional teams to ensure alignment and accoun...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$114K - $166K *

Champion the execution of warranty projects by leading teams, ensuring safety, quality, and efficiency in solar site operations while collaborating with various stakeholders to resolve issues and enha...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$83K - $107K *

Shape the future of clinical education by leading Epic EMR training initiatives. Collaborate with healthcare professionals to enhance patient care through effective training programs, ensuring optimal...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$83K - $107K *

Champion innovative solutions in Epic Home Care systems to enhance clinical workflows and patient outcomes. Collaborate with leaders, mentor teams, and drive strategic initiatives in a dynamic, remote...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.