Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$92K - $158K *

Drive innovative RFID solutions by leading design, customer engagement, and technical validation. Collaborate with teams to deliver reliable identification and tracking systems, ensuring alignment wit...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Business Services

$122K - $211K *

Champion the development of a secure, user-centric application for managing mission data and digital assets, ensuring seamless integration and collaboration while leading a team of developers in a dyn...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Business Services

$92K - $158K *

Empower cross-functional collaboration and operational efficiency in hardware development. Support project execution and coordination, ensuring alignment across teams while managing multiple prioritie...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$112K - $192K *

Join a dynamic team to develop and refine cost estimates for critical federal programs, ensuring effective budgetary decisions and enhancing national security through advanced technology solutions...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$140K - $200K *

Empower innovation by leading the design of secure, scalable Atlassian Cloud environments. This senior role involves architecture, migration strategy, and technical leadership to support modernization...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Business Services

$80K - $95K *

Champion complex LTC Professional Liability claims, managing them from inception to resolution. Collaborate with experts and leadership to shape strategies, ensuring effective outcomes in a high-stake...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$104K - $156K *

Lead the design, development, and integration of AI applications that enhance business operations. Collaborate with cross-functional teams to deliver technical solutions while maintaining security, re...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Information Technology

$89K - $109K *

Drive project accounting excellence by leading a team, ensuring accurate billing, and collaborating with project managers. Oversee financial reporting and client relations while mentoring junior staff...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $185K *

Unlock insights at scale by transforming complex healthcare data into actionable analytics solutions. Collaborate with cross-functional teams to design and optimize data models, ensuring high-quality...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$165K - $185K *

Lead the charge in healthcare data integration by analyzing source systems, designing database objects, and ensuring compliance with governance policies to support the Corporate Data Warehouse...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$94K - $120K *

Lead the charge in delivering impactful IT projects by managing all phases from initiation to closeout. Collaborate with diverse teams to ensure timely and successful project execution while aligning...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$385K - $416K *

Champion clinical expertise in birth defects research, overseeing case classification and quality control. Collaborate with multidisciplinary teams to ensure accurate data management and support publi...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$116K - $155K *

Transform enterprise applications through strategic architecture, integration, and governance. Collaborate with stakeholders to enhance business processes and ensure reliable operation of platforms wh...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$190K - $215K *

Engage in the design and development of robust full-stack solutions, guiding teams in secure engineering practices while integrating innovative technologies in a federal environment. Drive impactful c...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Manage complex digital investigations and data preservation efforts, leading a team in the collection and analysis of electronically stored information (ESI) while ensuring compliance with legal proto...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$74K - $91K *

Join our team to investigate healthcare fraud, waste, and abuse through data analysis. Utilize your expertise in Excel and communication skills to analyze cases, conduct interviews, and support legal...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$72K - $110K *

Grow your career with a dynamic sales team focused on driving market share and customer satisfaction across the Caribbean. Leverage your relationship-building skills to foster partnerships and deliver...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$72K - $110K *

Unlock potential by driving sales growth and building strong relationships in your territory. Collaborate with a dynamic team to deliver exceptional customer service and innovative solutions, while en...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$72K - $110K *

Lead the charge in driving sustainable sales growth and market share in your territory. Collaborate with retailers to implement product strategies and enhance customer satisfaction while building stro...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$155K - $175K *

Champion employee relations by leading a multi-site team, driving strategic oversight, and ensuring effective resolution of workplace issues while partnering with legal and HR functions to maintain co...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Transportation

$180K - $210K *

Drive strategic growth and operational excellence in IT program management, overseeing federal contracts and leading Agile teams to enhance supply chain solutions for the Department of Veterans Affair...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Information Technology

$80K - $120K *

Transform claims management by leveraging expertise in commercial casualty claims, focusing on product and premises liability. Collaborate with a dedicated team to deliver exceptional outcomes while m...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$180K - $220K *

Elevate your career by leading global marketing strategies that drive demand generation, enhance brand positioning, and support revenue growth in the healthcare technology sector. Collaborate with cro...

United StatesRemote

Reposted 5 days ago

  •   11 - 15 years exp.  •   Healthcare

$200K - $260K *

Unlock potential by driving new business sales in the Fintech sector, leveraging industry expertise to cultivate strategic relationships and deliver tailored solutions that meet client needs across No...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Business Services

$75K - $107K *

Unlock potential by delivering impactful training experiences that enhance audit quality and accuracy. Collaborate with clinical experts to translate complex guidelines into engaging learning material...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.