Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.
Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.
Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.
Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.
Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.
Average Salary: $110,033
$80K - $95K *
Unlock potential by driving operational excellence and enhancing business performance through strategic analysis, project management, and leadership development. Collaborate with cross-functional team...
5 days ago
Registered Nurse (RN) - Overnights
$88K *
Help us enhance lives by providing compassionate nursing care in a supportive environment. Join our dedicated overnight clinical team to make a meaningful impact on residents' well-being and foster a...
5 days ago
$90K - $110K *
Elevate your career by becoming a product expert in CommunitySuite, guiding clients through complex solutions, delivering tailored demos, and ensuring seamless transitions from sales to implementation...
5 days ago
Regional Sales Director - Knoxville
$180K - $215K *
Elevate regional sales performance by leading a high-performing team, executing launch strategies, and fostering customer relationships in a dynamic environment. Drive accountability and collaboration...
Reposted 5 days ago
$190K *
Lead the design and evolution of backend systems, tackling complex challenges while collaborating with cross-functional teams to deliver reliable, scalable solutions that enhance user experience and d...
5 days ago
Director, Intelligent Instruments & Automation
$200K - $230K *
Transform laboratory automation by leading the integration of intelligent workflows, AI, and interoperability standards to create scalable, innovative solutions that enhance scientific capabilities ac...
5 days ago
$110K - $130K *
Unlock your potential by supporting complex customer needs through expert solution design and seamless sales transitions. Collaborate with teams to drive sales opportunities and enhance customer engag...
5 days ago
Senior Associate, Compliance Model Governance
$148K - $175K *
Unlock potential by leading quantitative testing and monitoring for AI models in compliance, ensuring data quality and regulatory adherence while collaborating across teams to enhance financial crime...
5 days ago
$193K - $228K *
Lead the charge in transforming enterprise architecture by aligning technology with business goals, driving innovation, and managing technical debt to enhance application ecosystems and ensure scalabi...
5 days ago
Vice President, Chief Audit Executive (CAE)
$200K - $383K *
Join a team that's redefining internal audit excellence. Lead strategic initiatives, enhance risk management, and drive compliance while leveraging cutting-edge technologies to optimize processes and...
5 days ago
User Experience Operations Lead
$177K - $290K *
Transform UX operations by unifying decision-making and enhancing workflows across disciplines. Drive continuous improvement through automation and strategic partnerships, ensuring a cohesive UX organ...
Reposted 5 days ago
$140K - $160K *
Advance the design and implementation of a robust knowledge architecture for K-12 assessment systems, integrating AI and learning science to enhance educational outcomes through innovative, data-drive...
5 days ago
Senior, Influencer Manager - Creative - US Remote
$85K - $115K *
Transform creator-driven ideas into high-quality deliverables by managing influencer campaigns, coordinating production workflows, and ensuring compliance across multiple platforms. Collaborate with c...
5 days ago
ARPA-H Senior Scientist / Engineer (Regenerative Medicine & Advanced Biological Systems)
$125K - $185K *
Elevate health outcomes by collaborating on innovative R&D initiatives, supporting program development, and integrating advanced biological systems with cutting-edge technologies in a dynamic, remote...
5 days ago
Director, Consumer Marketing & Strategy
$162K - $211K *
Join a team that's redefining consumer marketing strategies in healthcare. Drive impactful initiatives that enhance patient engagement and awareness while collaborating across functions to shape the f...
5 days ago
Early Phase Clinical Project Manager
$110K - $130K *
Join a team that's dedicated to leading interdisciplinary clinical research projects, ensuring compliance with regulatory standards, and delivering quality results on time and within budget while fost...
5 days ago
Associate Director/Director Process Chemistry
$177K - $205K *
Lead the charge in advancing drug substance processes by collaborating with CDMOs and internal teams to ensure timely delivery and adherence to regulatory standards, while providing technical expertis...
5 days ago
Director, Brand Marketing - SWTHZ
$110K - $130K *
Elevate the SWTHZ brand by leading PR, partnerships, and social strategies. Collaborate with creative teams to craft a compelling narrative, engage communities, and drive brand recognition through inn...
5 days ago
Account Executive - Healthcare
$200K - $255K *
Elevate your career by driving new business in healthcare accounts. Engage with C-level executives, navigate complex sales cycles, and close high-value deals to expand market presence and achieve reve...
Reposted 5 days ago
Senior Software Engineer - Machine Learning Platform
$166K - $230K *
Innovate and enhance the machine learning infrastructure to empower rapid model deployment and automation. Collaborate across teams to streamline operations and drive impactful solutions in ML and fin...
Reposted 5 days ago
Account Executive - Midwest / Central
$80K - $95K *
Join a dynamic sales team to drive growth in K-12 education, managing the full sales cycle and building strategic partnerships. Shape your territory strategy while enhancing digital learning environme...
5 days ago
Automation and Controls - Project Engineer-
$80K - $95K *
Drive the successful planning and execution of automation projects, enhancing manufacturing efficiency and safety. Collaborate with teams to optimize processes and implement improvements across multip...
5 days ago
Automation and Controls - Project Engineer-
$80K - $95K *
Elevate automation projects by leading design, commissioning, and support for manufacturing systems. Collaborate with teams to enhance safety, quality, and efficiency while driving cost-effective solu...
5 days ago
Staff Data Engineer, Core Migrations
$230K - $260K *
Lead the charge in client migrations, owning the entire technical lifecycle from legacy analysis to deployment, ensuring precision and collaboration across teams for optimal outcomes...
Reposted 5 days ago
$59K - $110K *
Engage with patients and caregivers to enhance their treatment journey through education and support. Collaborate with teams to ensure quality service and compliance while driving innovative solutions...
5 days ago
What kinds of $100,000+ jobs are available in Iowa?
Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.
Which Iowa cities have professional jobs listed?
Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.
Are all jobs on this page guaranteed to pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.
How can I find the right high-paying job in Iowa?
Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.