Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,075

Sort By: Relevance

$79K - $98K *

Join us to lead product management for our Medicare Part D program, ensuring compliance with CMS regulations while enhancing processes and client satisfaction. Your expertise will drive operational ex...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Elevate member health through tele-pharmacy by developing clinical programs, providing outreach, and collaborating with healthcare teams to enhance care coordination and adherence to medication guidel...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$135K - $216K *

Shape the future of air traffic management by integrating modern display technology for the FAA. Collaborate with experts to enhance safety and efficiency in the National Airspace System through innov...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Aerospace & Defense

$135K - $216K *

Drive the modernization of air traffic management systems by integrating data and display technologies. Collaborate with FAA teams to enhance safety and efficiency in the National Airspace System thro...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Aerospace & Defense

$135K - $216K *

Partner with us to enhance the National Airspace System by ensuring timely upgrades and installations. Collaborate with FAA and vendors to implement cutting-edge technology, ensuring safety and effici...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Aerospace & Defense

$66K - $106K *

Transform organizational communications by crafting clear, concise technical documents and managing SharePoint resources. Collaborate with teams to ensure quality and consistency in messaging while su...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$104K - $166K *

Shape the future of database management by supporting and enhancing DB2 environments. Leverage your expertise in administration, troubleshooting, and SQL development to ensure optimal performance acro...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$220K - $245K *

Tackle financial strategy and analysis for a leading Wellbeing business. Collaborate with leadership to enhance member engagement and operational efficiency, driving growth through insightful financia...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$165K - $210K *

Transform retail sales strategies and lead a dynamic team to achieve revenue goals. Drive account management, develop talent, and collaborate with cross-functional teams to enhance product offerings a...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$61K - $119K *

Join a team that's dedicated to empowering clients through personalized financial planning. As a financial advisor, you'll build relationships, create tailored strategies, and drive your entrepreneuri...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$180K - $207K *

Innovate AI and ML systems as a Principal Architect, collaborating with teams to design agentic architectures and scalable solutions. Drive production delivery while shaping standards and best practic...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$83K - $161K *

Join us to lead testing efforts on complex software projects, mentor junior engineers, and collaborate with cross-functional teams to ensure high-quality products meet all functional, performance, and...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Elevate customer insights by analyzing complex data to drive retention strategies. Collaborate with senior leaders to present actionable recommendations that enhance customer experience and operationa...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Drive transformational growth by managing critical customer relationships and partnerships. Leverage AI insights to shape enterprise strategies, influence executive decisions, and mentor sales profess...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Technical Services

$85K - $95K *

Develop and deliver engaging training programs to enhance user adoption and operational excellence. Collaborate with diverse teams to create effective learning solutions, ensuring content aligns with...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$185K - $275K *

Transform the future of IT programs by leading a dynamic team in planning, budgeting, and compliance. Drive performance and innovation while ensuring alignment with organizational goals in a fully rem...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$95K - $115K *

Lead the charge in managing engineering and manufacturing projects, collaborating across teams to ensure timely execution, budget adherence, and high-quality outcomes that drive business growth and in...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$116K - $164K *

Engineer comprehensive land development projects for EV and AV charging stations. Oversee design, permitting, and construction phases while managing budgets and client communications. Collaborate with...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$95K *

Advance your career by auditing outpatient and specialty claims, ensuring coding accuracy and compliance. Leverage your clinical and coding expertise to enhance audit processes and contribute to quali...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Lead the charge in transforming healthcare revenue cycles by optimizing financial operations, ensuring compliance, and enhancing patient experiences. Drive strategic initiatives and foster collaborati...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$175K - $210K *

Transform the accounting landscape by leading a multi-disciplinary team, enhancing operational efficiency, and driving innovation through AI and automation while ensuring compliance and integrity in f...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Drive impactful decision-making and support for EHRM initiatives, enhancing operational efficiency and stakeholder engagement through strategic analysis, project management, and effective communicatio...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Shape the future of healthcare IT by managing complex integration programs, driving Lean-Agile adoption, and ensuring successful delivery of enterprise reporting and analytics initiatives across multi...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Healthcare

$70K - $120K *

Drive data analytics to enhance audit and compliance processes, leveraging technical skills to improve efficiency and risk management across various assurance activities. Collaborate with cross-functi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$162K - $195K *

Join a team that's dedicated to launching innovative cardiac therapies. Drive sales performance, build strategic relationships, and serve as a key resource in your territory, focusing on patient needs...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.