Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$75K - $90K *

Drive impactful SEM strategies to enhance online visibility and conversions. Collaborate with diverse clients, analyze data, and optimize campaigns to exceed goals while staying ahead of industry tren...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Unlock potential by leading social commerce strategies across platforms like TikTok, Instagram, and YouTube. Drive revenue growth and optimize customer experiences through innovative, data-driven appr...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by leading development initiatives in healthcare technology, focusing on SYNON and AS400 systems. Collaborate with teams to deliver high-quality solutions for pharmacy benefits and cl...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Transform financial operations by leading accounting, reporting, and FP&A. Drive efficiency through AI integration, manage audits, and build scalable processes while supporting strategic growth initia...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$180K - $215K *

Inspire growth by leading regional launch strategies and building high-performing sales teams. Drive market success through strong customer relationships and cross-functional collaboration in a fast-p...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$215K - $240K *

Drive scientific engagement as a Senior Medical Science Liaison, fostering relationships with Key Opinion Leaders and healthcare professionals. Leverage your expertise in cardiovascular disease to sup...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Transform your career by leading regional sales efforts, driving product launch success, and building high-performing teams. Collaborate cross-functionally to achieve sales goals and foster strong cus...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$158K - $248K *

Unlock potential by architecting scalable file management solutions, integrating distributed systems, and ensuring secure access for enterprise customers. Collaborate across teams to enhance data acce...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$172K - $269K *

Lead and modernize global security operations, managing a distributed team while enhancing detection strategies and incident response. Drive AI integration for efficiency and ensure accountability thr...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$179K - $280K *

Shape the future of product marketing by leading a dynamic team focused on innovation, market resonance, and compelling narratives to drive product adoption and growth in a fast-paced environment...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$253K - $342K *

Join a team that's redefining pricing and packaging strategies to drive customer value and profitable growth. Lead cross-functional collaboration and influence key decisions that shape the future of m...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Lead the administration of diverse ETFs, ensuring compliance and accuracy while mentoring a team. Collaborate cross-functionally to enhance operational processes and support fund operations in a dynam...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $110K *

Collaborate with cross-functional teams to manage ETF fund administration, ensuring compliance with SEC regulations while preparing financial statements and regulatory filings. Adapt to evolving prior...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $150K *

Empower a safe work environment by leading industrial hygiene projects, ensuring compliance, and fostering team growth. Utilize your expertise to address health and safety issues while mentoring staff...

RemoteRemote

5 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$180K - $200K *

Elevate your career by driving growth strategies that enhance lead generation for multiple brands. Collaborate with cross-functional teams to optimize acquisition channels and improve conversion rates...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$66K - $103K *

Engage in impactful infrastructure projects as a Transportation Engineer Associate. Collaborate with seasoned professionals to ensure quality and safety in roadway and bridge construction, while advan...

5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$90K - $110K *

Help us shape the future of infrastructure by leveraging your cost estimating expertise in a collaborative, multi-disciplinary team, empowering positive community impact through precise project contro...

RemoteRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Technical Services

$190K - $215K *

Elevate your career by leading the development of AI-enabled Medical Information strategies. Drive high-quality responses, oversee scientific content, and collaborate cross-functionally to ensure laun...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $161K *

Shape the future of power systems engineering by leading advanced studies, consulting, and technology initiatives. Collaborate with utilities and industry organizations to tackle complex challenges an...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$186K *

Unlock potential by leading the design and delivery of innovative risk systems, optimizing fraud detection and mitigation processes, and mentoring engineers to enhance operational excellence in a dyna...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in optimizing our Epic systems as a Senior Application Advisor, guiding a dedicated team in enhancing patient access and delivering exceptional service to clients while fostering colla...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $237K *

Join a dynamic team to design and deploy cutting-edge machine learning models that enhance personalization and recommendations, driving impactful solutions across diverse datasets and collaborating wi...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$130K - $150K *

Empower our cybersecurity initiatives by providing strategic leadership and ensuring compliance with DoD standards. Drive enterprise-level security architecture and risk management across multiple Tas...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$350K - $400K *

Optimize enterprise sales growth by leading a high-performing team, refining strategies, and driving revenue. Collaborate across departments to enhance processes and ensure long-term success in a dyna...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$85K - $100K *

Unlock new revenue streams by cultivating partnerships and driving sales growth through effective channel management and collaboration with internal teams in a dynamic environment...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.