Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$162K - $211K *

Join a team that's redefining consumer marketing strategies in healthcare. Drive impactful initiatives that enhance patient engagement and awareness while collaborating across functions to shape the f...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to leading interdisciplinary clinical research projects, ensuring compliance with regulatory standards, and delivering quality results on time and within budget while fost...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$177K - $205K *

Lead the charge in advancing drug substance processes by collaborating with CDMOs and internal teams to ensure timely delivery and adherence to regulatory standards, while providing technical expertis...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate the SWTHZ brand by leading PR, partnerships, and social strategies. Collaborate with creative teams to craft a compelling narrative, engage communities, and drive brand recognition through inn...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$200K - $255K *

Elevate your career by driving new business in healthcare accounts. Engage with C-level executives, navigate complex sales cycles, and close high-value deals to expand market presence and achieve reve...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Business Services

$166K - $230K *

Innovate and enhance the machine learning infrastructure to empower rapid model deployment and automation. Collaborate across teams to streamline operations and drive impactful solutions in ML and fin...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Join a dynamic sales team to drive growth in K-12 education, managing the full sales cycle and building strategic partnerships. Shape your territory strategy while enhancing digital learning environme...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Drive the successful planning and execution of automation projects, enhancing manufacturing efficiency and safety. Collaborate with teams to optimize processes and implement improvements across multip...

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Elevate automation projects by leading design, commissioning, and support for manufacturing systems. Collaborate with teams to enhance safety, quality, and efficiency while driving cost-effective solu...

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$230K - $260K *

Lead the charge in client migrations, owning the entire technical lifecycle from legacy analysis to deployment, ensuring precision and collaboration across teams for optimal outcomes...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Information Technology

$59K - $110K *

Engage with patients and caregivers to enhance their treatment journey through education and support. Collaborate with teams to ensure quality service and compliance while driving innovative solutions...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$58K - $108K *

Join a team that's dedicated to enhancing patient experiences through compassionate support and education in Hepatology. Engage with patients and caregivers, providing vital resources and guidance thr...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Business Services

$105K - $135K *

Lead financial planning and analysis efforts, partnering with business leaders to drive strategic insights, enhance decision-making, and improve operational excellence through data-driven financial mo...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$96K - $115K *

Lead the charge in designing and developing aerospace wire harnesses, ensuring compliance with industry standards while collaborating with multidisciplinary teams to deliver innovative solutions...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$114K - $218K *

Transform the construction industry by leveraging geospatial technology to enhance customer relationships and optimize strategies for growth. Collaborate with experts and use your industry insights to...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $100K *

Tackle the administration of nursing programs in a long-term care facility, ensuring high standards of resident care and compliance with regulations while optimizing geriatric care processes and leadi...

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Optimize product operations by driving launches, enhancing documentation, and improving customer experiences. Collaborate with cross-functional teams to ensure seamless feature adoption and leverage c...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Media

$70K - $106K *

Transform warehouse operations by leading a dedicated team, ensuring compliance, safety, and efficiency in a dynamic environment. Drive talent development and maintain strong relationships with intern...

5 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$95K - $115K *

Elevate your career by owning IT operations, enhancing security, and automating workflows in a fully remote environment. Collaborate with teams to resolve complex issues and streamline processes while...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$133K - $200K *

Champion the delivery of advanced manufacturing capabilities by leading cross-functional teams, managing project lifecycles, and ensuring alignment with customer and stakeholder expectations for succe...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Business Services

$108K - $130K *

Drive operational excellence by coordinating plant functions to ensure top-quality products and services. Collaborate with teams to meet objectives, manage budgets, and uphold compliance standards whi...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Food & Beverages

$132K - $194K *

Unlock potential by leading the strategy and evolution of People technology and analytics. Drive data governance and insights to enhance decision-making and operational efficiency, while partnering wi...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Information Technology

$75K - $90K *

Drive impactful SEM strategies to enhance online visibility and conversions. Collaborate with diverse clients, analyze data, and optimize campaigns to exceed goals while staying ahead of industry tren...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Unlock potential by leading social commerce strategies across platforms like TikTok, Instagram, and YouTube. Drive revenue growth and optimize customer experiences through innovative, data-driven appr...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by leading development initiatives in healthcare technology, focusing on SYNON and AS400 systems. Collaborate with teams to deliver high-quality solutions for pharmacy benefits and cl...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.