Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$120K - $145K *

Shape the future of healthcare technology by developing scalable AI solutions. Collaborate with experts to create impactful systems, enhancing user experiences and driving innovation in clinical data...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $141K *

Execute integrated marketing strategies that drive measurable growth by translating business priorities into actionable programs. Collaborate cross-functionally to enhance pipeline performance and lev...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$134K - $201K *

Inspire growth within the cell and gene therapy landscape by driving complex CDMO deal lifecycle, leveraging your expertise in CGT and forging senior relationships to accelerate innovative partnership...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Empower product excellence by connecting teams and building systems that ensure reliability and efficiency. Drive customer insights, streamline operations, and enhance product launches in a hands-on...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's driving revenue growth by developing innovative sales strategies for K-12 education solutions. Collaborate with schools to enhance student outcomes and build lasting relationships w...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Lead the design and governance of compensation strategies, ensuring market competitiveness and compliance. Oversee a team to deliver innovative solutions that align with business objectives and enhanc...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$104K - $176K *

Lead the strategy and optimization for a high-traffic B2B website, aligning partners and driving performance through experimentation and content governance. Collaborate with cross-functional teams to...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$166K - $200K *

Help us deliver exceptional primary care services to Veterans by providing comprehensive clinical practice, consultation, and management within a collaborative healthcare team, ensuring quality and ti...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Manage the preparation and review of diverse tax returns while mentoring a team. Embrace challenges in a fast-paced environment, ensuring accuracy and compliance with tax codes. Foster client relation...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$150K - $180K *

Unlock potential by leading multidisciplinary engineering teams to design and deploy complex power generation systems. Drive strategic initiatives, ensure technical excellence, and foster collaboratio...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Energy & Utilities

$210K - $250K *

Transform patient care by providing emergency medical services in a dynamic environment. Collaborate with a dedicated team to ensure high-quality treatment and participate in special projects that enh...

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$88K - $105K *

Join a team that's dedicated to executing hyperscale projects with a focus on safety, quality, and customer satisfaction. Manage complex scopes and ensure compliance with standards while fostering an...

4 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$150K - $180K *

Drive the development of cutting-edge AI tax agents, collaborating with engineers and clients to enhance efficiency and transform tax practices across the industry. Shape product strategy and deliver...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Empower our growth by driving transportation sales, managing key accounts, and executing strategic initiatives to enhance our bundled service offerings while collaborating with cross-functional teams...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$132K - $193K *

Unlock potential by architecting complex analytics solutions, mentoring analysts, and collaborating with senior stakeholders to deliver impactful insights across multiple domains, ensuring high standa...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$85K - $110K *

Explore your potential in a dynamic role driving outbound outreach and building relationships. You'll engage with security leaders, turning interest into qualified meetings while collaborating closely...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $160K *

Empower enterprise customers by managing onboarding, adoption, and expansion strategies. Collaborate with sales and technical teams to ensure successful implementations and drive measurable outcomes f...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$87K - $95K *

Elevate patient care by assessing and treating diverse cases in a dynamic clinic. Collaborate with a skilled team, utilize advanced technology, and enjoy a supportive environment that fosters professi...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $170K *

Transform the future of genomics by driving strategic partnerships and large-scale research projects with pharmaceutical and biotech companies. Leverage your extensive network to identify opportunitie...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform patient care as a vital pharmacist in a high-throughput environment. Collaborate with prescribers, verify prescriptions, and provide exceptional patient counseling to enhance outcomes and en...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Join a team that's launching a federal vertical, setting strategy, winning agency customers, and building a sales team. You'll lead initial pursuits, collaborate with key stakeholders, and shape our a...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$125K - $150K *

Shape the future of application operations by leading critical production services, ensuring reliability and governance across diverse platforms. Drive continuous improvement and operational excellenc...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Transform enterprise communications by leading the design, deployment, and support of Cisco UC Manager and SBC platforms. Collaborate with cross-functional teams to enhance network infrastructure and...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $150K *

Empower labor relations across diverse construction projects by fostering strong partnerships with unions and project teams. Ensure compliance with agreements and resolve employee relations issues to...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$175K - $210K *

Drive the enterprise data strategy and governance, ensuring data quality, compliance, and accessibility. Lead cross-functional teams to foster a data-rich culture, enabling advanced analytics and AI r...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.