Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$75K - $90K *

Drive recruitment, development, and retention efforts across multiple sites, ensuring effective staffing and engagement for optimal team performance. Collaborate with managers to enhance onboarding, t...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Champion employment law compliance and support HR initiatives in a dynamic startup. Collaborate with management and People Operations to address legal matters, streamline processes, and ensure best pr...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$65K - $181K *

Drive success by providing high-level executive support in a dynamic environment. Collaborate with cross-functional teams, manage complex schedules, and enhance organizational efficiency while maintai...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$145K - $180K *

Champion operational excellence by leading a dynamic team to enhance processes, drive complex projects, and ensure seamless collaboration across departments, all while improving patient outcomes in th...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$92K - $128K *

Transform partnership operations by managing billing, benefit administration, and cross-functional projects. Leverage your organizational skills to enhance member experiences and streamline processes...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $145K *

Join a team that's dedicated to enhancing client operations and driving revenue cycle success. Lead initiatives, foster relationships, and ensure performance excellence while collaborating with stakeh...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$250K - $289K *

Transform AI/ML engineering by leading innovative platform design and implementation, ensuring reliability and scalability to meet growing needs while collaborating across teams to drive business impa...

United StatesRemote

Reposted 4 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$95K - $115K *

Elevate pharmacy operations by supervising staff and ensuring compliance. Lead daily functions, resolve conflicts, and implement strategic solutions to enhance efficiency and team performance in a dyn...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Shape the future of cybersecurity by leading verification and validation efforts across industrial environments. Drive technical assessments, develop procedures, and ensure compliance with cybersecuri...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $130K *

Join us to take technical ownership of our global WordPress platform, enhancing performance and scalability. Collaborate with cross-functional teams to develop custom solutions and ensure a seamless u...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $150K *

Unlock potential by leading software engineering initiatives, mentoring junior engineers, and driving improvements in development processes. Collaborate with stakeholders to deliver impactful solution...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K - $248K *

Shape the future of connected devices as the product leader for in-field asset monitoring. Own the hardware roadmap, drive product introductions, and ensure reliability, directly influencing a key gro...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's dedicated to transforming data into actionable insights. As a Senior Analyst, you'll tackle complex challenges, support strategic initiatives, and collaborate with experts to enhanc...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$132K - $251K *

Lead the charge in shaping mission-critical avionics software for the KC-46 Video Graphics System. Drive a high-performing team to deliver robust, certifiable software that enhances aircrew situationa...

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$86K - $165K *

Join a dynamic team to design and develop innovative flight management software for military applications, leveraging your expertise in software engineering within a collaborative AGILE environment fo...

4 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $147K *

Analyze and contribute to local market strategies by researching regulatory conditions and trends. Collaborate across teams to ensure product compliance and support implementation, while effectively c...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$50K - $114K *

Transform financial operations by driving budgeting, forecasting, and reporting processes. Collaborate with stakeholders to ensure accuracy and alignment in workforce planning, while supporting leader...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Shape the future of healthcare technology by developing scalable AI solutions. Collaborate with experts to create impactful systems, enhancing user experiences and driving innovation in clinical data...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $141K *

Execute integrated marketing strategies that drive measurable growth by translating business priorities into actionable programs. Collaborate cross-functionally to enhance pipeline performance and lev...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$134K - $201K *

Inspire growth within the cell and gene therapy landscape by driving complex CDMO deal lifecycle, leveraging your expertise in CGT and forging senior relationships to accelerate innovative partnership...

United StatesRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Empower product excellence by connecting teams and building systems that ensure reliability and efficiency. Drive customer insights, streamline operations, and enhance product launches in a hands-on...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's driving revenue growth by developing innovative sales strategies for K-12 education solutions. Collaborate with schools to enhance student outcomes and build lasting relationships w...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Lead the design and governance of compensation strategies, ensuring market competitiveness and compliance. Oversee a team to deliver innovative solutions that align with business objectives and enhanc...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$104K - $176K *

Lead the strategy and optimization for a high-traffic B2B website, aligning partners and driving performance through experimentation and content governance. Collaborate with cross-functional teams to...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$166K - $200K *

Help us deliver exceptional primary care services to Veterans by providing comprehensive clinical practice, consultation, and management within a collaborative healthcare team, ensuring quality and ti...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.