Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$100K - $120K *

Contribute to the evolution of Support Operations by leading system implementations, optimizing workflows, and enhancing team collaboration. Own the configuration and administration of support systems...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Elevate data engineering by managing pipelines and operations, collaborating with stakeholders to define architecture, and driving project plans for optimal data solutions. Lead teams to ensure data q...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$85K - $158K *

Join a team that's transforming user experiences through innovative digital adoption solutions. Collaborate with stakeholders to design, implement, and enhance in-app guidance, ensuring seamless user...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$202K - $291K *

Lead the charge in strategic program management for the CFO, driving cross-functional initiatives, AI adoption, and operational excellence across Finance and beyond. Shape the future of a fast-growing...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Information Technology

$90K - $175K *

Empower mission success by managing COMSEC lifecycle functions, ensuring the security and integrity of communication systems through expert oversight and compliance with national standards...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$132K - $145K *

Transform clinical data into actionable insights, bridging stakeholders and data teams to enhance quality, safety, and research analytics. Drive enterprise improvements through innovative data solutio...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$141K - $251K *

Champion enterprise data storage transformation by architecting complex subscription agreements. Collaborate with strategic leaders and engage C-suite executives to drive recurring revenue and redefin...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Join a team that's dedicated to providing technical support and guidance in membrane systems. Collaborate across departments to optimize solutions, assist customers, and enhance product performance th...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$170K - $272K *

Lead and innovate within a dynamic team, driving strategic initiatives and managing cross-functional projects to enhance service offerings and achieve business objectives...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$80K - $95K *

Transform your career by leading implementation projects in healthcare. Drive successful onboarding and training for Ambulatory Surgery Centers, ensuring optimal system configurations and revenue cycl...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $180K *

Lead strategic program management initiatives, ensuring alignment and governance across a complex portfolio while driving results in a dynamic technical environment. Collaborate with cross-functional...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Unlock potential by leading new business acquisition and expansion efforts in a dynamic sales environment. Engage key stakeholders to position solutions that drive scalable growth and manage risk effe...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $150K *

Lead strategic pricing initiatives, enhancing processes and analytics to drive profitable growth and informed decision-making across business functions. Collaborate with teams and cultivate a high-imp...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Business Services

$225K - $245K *

Lead the charge in shaping analytics for sales and partnerships, driving insights that enhance revenue strategies. Collaborate with executives to translate data into actionable decisions, fostering a...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Business Services

$80K - $120K *

Join a team that's dedicated to enhancing educational outcomes for English learners. This role involves consultative sales, relationship building, and managing a full-cycle sales process in the K-12 s...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Transform customer relationships in the food, pharmaceutical, and personal care sectors by driving growth through strategic partnerships and innovative solutions. Collaborate with cross-functional tea...

4 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$90K - $110K *

Join a team that's driving growth by cultivating strategic customer relationships in the food, pharmaceutical, and personal care sectors. Leverage your sales expertise to expand market share and deliv...

4 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$110K - $130K *

Join a team that's enhancing security across network, cloud, and infrastructure. This hands-on role focuses on implementing and managing security controls, troubleshooting complex issues, and collabor...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$179K - $350K *

Lead the strategy and execution of EMR integrations, enhancing processes and team performance while managing client relationships and driving innovation in healthcare data solutions...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Redefine regulatory excellence by leading IND/IDE submissions, ensuring compliance, and collaborating with multidisciplinary teams to advance innovative therapies in a remote setting...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform operations by leading maintenance strategies to enhance productivity and safety in a high-volume manufacturing environment. Drive continuous improvement and foster team development while ens...

4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$130K - $150K *

Drive enterprise sales success by building a robust pipeline, managing complex deals, and leveraging AI tools to enhance productivity. Collaborate cross-functionally to deliver tailored solutions and...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$73K - $95K *

Champion the efficient operation of IT infrastructure, leading a team to ensure optimal performance, drive incident resolution, and implement improvements that enhance service quality for team members...

4 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$145K - $201K *

Pioneer a robust quality oversight program for unsecured lending, leading end-to-end testing and collaborating across teams to ensure compliance with regulatory standards while driving continuous impr...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$91K - $145K *

Champion third-party risk management by assessing supplier risks, collaborating with stakeholders, and enhancing processes. Drive improvements in frameworks and tools to ensure compliance and operatio...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.