Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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1,000+

Jobs in Iowa

Average Salary in USD

Average Salary: $110,033

Sort By: Relevance

$95K - $115K *

Drive innovation in clinical research by managing and optimizing information systems. Collaborate with multidisciplinary teams to ensure compliance and enhance data security while supporting genomic a...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Shape the future of social and behavioral research by leveraging advanced statistical methods and collaborating with multidisciplinary teams to analyze complex data and support impactful NIH-funded pr...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to enhancing customer trust through effective escalation management. You'll coordinate complex incidents, advocate for clients, and lead resolution efforts across multiple...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Elevate customer success by leading a dynamic team focused on adoption, satisfaction, and advocacy. Collaborate across departments to enhance customer relationships and drive measurable outcomes while...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$192K - $252K *

Lead the execution of global medical strategies for hematology, ensuring patient-centered, evidence-driven activities. Collaborate with cross-functional teams to enhance scientific exchange and optimi...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $160K *

Oversee and manage a portfolio of complex Management Liability claims, including D&O, EPL, and Fiduciary Liability. Leverage technical expertise and strong judgment to achieve superior outcomes while...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$83K - $130K *

Champion innovation in healthcare by leveraging informatics to enhance clinical workflows, support EHR initiatives, and drive process improvements. Collaborate with diverse teams to ensure technology...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Drive cloud onboarding success by guiding application owners through migration complexities, ensuring effective communication and collaboration across teams to enhance operational efficiency and suppo...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $168K *

Champion strategic initiatives to scale partner operations, leading a global team to drive growth and enhance capabilities through effective execution and collaboration across functions...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Business Services

$144K - $222K *

Contribute to data-driven marketing strategies by analyzing insights, guiding teams, and identifying growth opportunities in pharma. Collaborate with leadership to enhance analytics capabilities and d...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in transforming employer benefits by driving sales growth in the Mid-Atlantic region. Collaborate with teams to manage client relationships and contribute to product development while...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$95K - $115K *

Lead the educational vision and operations of a school district, ensuring effective programs and compliance with regulations. Collaborate with the Board to enhance student achievement and manage fisca...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$74K - $112K *

Engineer innovative autonomy solutions for agricultural equipment, tackling complex software challenges from concept to production while ensuring quality and continuous improvement in guidance systems...

3 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $190K *

Unlock potential by leading the design and integration of advanced satellite communications systems. Drive system architecture, manage requirements, and collaborate across multi-disciplinary teams to...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$92K *

Lead dynamic business growth by building relationships and delivering tailored wireless solutions. Collaborate with local business owners to drive success and maximize earning potential through strate...

3 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$150K - $180K *

Drive impactful financial solutions by leading teams and transforming data into strategic insights. Collaborate with stakeholders to enhance processes and deliver high-quality results that support inf...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Join a team that's driving innovative media strategies and partnerships. Oversee planning and execution of media investments across diverse channels, ensuring alignment with client objectives while fo...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$132K - $150K *

Drive growth by building relationships with emerging dietary supplement brands, connecting customer ambitions with innovative solutions, and advancing projects from concept to commercialization across...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $173K *

Join us to build a robust Product Intelligence function, transforming complex data into actionable insights. You'll define key questions, create data infrastructure, and influence product decisions, s...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Technical Services

$72K - $90K *

Champion the mental health of older adults by providing tailored teletherapy. Enjoy flexible scheduling, a supportive team, and a full caseload built for you. Focus on meaningful therapy while we hand...

Iowa, USRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Support client development efforts by providing Hogan IDS expertise. Collaborate on technical design, coding, and testing while ensuring smooth production migration. Leverage your extensive experience...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $200K *

Elevate your career by leading a $3M-5M client portfolio, driving strategic initiatives and fostering strong relationships. Collaborate with diverse teams to deliver exceptional results while managing...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Media

$80K - $95K *

Join a team that's dedicated to enhancing credit administration through effective loan portfolio management, risk evaluation, and staff development. Lead initiatives that ensure compliance and high-qu...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$87K - $128K *

Engage in strategic brand development and campaign execution, translating marketing strategies into impactful creative work. Collaborate across teams to enhance employee and member experiences through...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$119K - $169K *

Elevate customer engagement by shaping compelling narratives for high-value opportunities. Collaborate with Sales and cross-functional teams to create memorable experiences that clearly communicate va...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.