Explore $100K+ Jobs in Illinois

Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.

Career Opportunities Across Illinois

Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.

Find a Role That Fits Your Experience

Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.

Advance Your Career in Illinois

Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.

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1,000+

Jobs in Illinois

Average Salary in USD

Average Salary: $117,810

Sort By: Relevance

$55K - $120K *

Join a team that's dedicated to enhancing risk management frameworks and compliance. Collaborate with stakeholders to design and implement effective controls across various risk types, ensuring alignm...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$168K - $240K *

Lead the charge in optimizing business operations through innovative solutions, driving efficiency and productivity while fostering cross-functional collaboration and data-driven decision-making to en...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$224K - $336K *

Shape the future of Digital Power by leading strategic accounts and driving growth. Collaborate with a dynamic team to enhance market strategies, engage with key customers, and navigate organizational...

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Engineer robust security solutions by assessing web applications and APIs. Leverage your expertise in OWASP and SANS frameworks to identify vulnerabilities, conduct thorough testing, and enhance secur...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$108K - $148K *

Join a team that's shaping the future of supply chain management by leading procurement operations and driving efficiency in global inbound networks. Empower your team to implement innovative strategi...

Today

  •   5 - 7 years exp.  •   Food & Beverages

$100K - $120K *

Unlock potential by partnering with ABA practice owners to enhance operations, drive growth, and improve performance. Collaborate closely with providers to navigate challenges and implement strategic...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$85K - $105K *

Join us to analyze and adjudicate complex workers compensation claims, delivering innovative solutions in a dynamic environment. Collaborate with clients across industries while enjoying professional...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Drive product strategy and execution for a critical portfolio area, leading cross-functional teams to transform user insights into impactful software solutions while mentoring others and shaping platf...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Lead the charge in shaping product marketing strategies that drive adoption and pipeline. Collaborate with cross-functional teams to craft compelling narratives and ensure our differentiated value res...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$125K - $165K *

Pioneer growth by leading technology sales initiatives, managing proposals, and negotiating contracts. Collaborate with internal teams to ensure client satisfaction and drive successful deal closures...

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$130K - $140K *

Elevate your career by joining a dynamic team to design and implement innovative cloud solutions in a multi-cloud environment, ensuring scalability, security, and alignment with business objectives wh...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$162K - $203K *

Champion scientific engagement by building relationships with key opinion leaders in Urology and Women's Health. Leverage expertise to support medical strategies and enhance product knowledge across t...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Elevate employee experiences by designing and implementing HR solutions. Lead technical projects, optimize integrations with Microsoft 365, and mentor developers to enhance ServiceNow capabilities and...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$118K - $196K *

Lead the charge in managing the full patent lifecycle for innovative medical technologies. Collaborate with R&D teams, assess IP risks, and enhance portfolio strategies to drive product development an...

Today

  •   8 - 10 years exp.  •   Healthcare

$156K - $212K *

Support healthcare partners by educating on clinical data and advancing scientific initiatives in cardiometabolic health. Collaborate with key stakeholders to enhance patient outcomes and drive organi...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $220K *

Join us to lead AI-driven enterprise architecture and cloud solutions in healthcare. Leverage your expertise in GCP, Generative AI, and system integration to create scalable, innovative solutions that...

Today

  •   11 - 15 years exp.  •   Staffing

$150K - $180K *

Champion the growth of our commercial engine by leading business development efforts, forging strategic partnerships, and driving revenue as quantum computing transitions to enterprise applications. C...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$170K - $250K *

Shape the future of eye care by driving product adoption and building partnerships with healthcare professionals. Collaborate with cross-functional teams to implement strategies that enhance customer...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $185K *

Architect comprehensive clinical supply strategies for global trials. Collaborate across functional teams to secure timely, compliant drug supply while managing risks and inventory effectively, ensuri...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$115K - $140K *

Drive operational excellence in commercial readiness and support cross-functional teams to ensure effective execution of launch strategies and operational priorities in a dynamic biotech environment...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$225K - $275K *

Optimize quality assurance processes to ensure compliance with regulatory standards and drive improvements across all operations. Lead a talented team to establish and maintain an effective Quality Ma...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$92K - $139K *

Elevate customer success by managing a portfolio of enterprise accounts, ensuring optimal software utilization, and fostering strong relationships. Collaborate with clients to solve complex challenges...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Shape the future of affordable housing by managing a diverse real estate portfolio, ensuring financial performance, and collaborating with partners to adapt business plans while safeguarding investor...

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$172K - $215K *

Empower the evolution of enterprise-level Risk Management analytics and reporting. Lead a high-performing team to deliver critical insights to executives and regulators, ensuring data integrity and st...

Today

  •   11 - 15 years exp.  •   Finance & Insurance

$90K - $180K *

Join a dynamic team to oversee facilities maintenance operations, ensuring efficient and sustainable building performance. Lead a skilled group of technicians while collaborating with management to en...

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Illinois?question toggle

    Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.

  • Are there high-paying jobs outside Chicago?question toggle

    Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.

  • How can I find Illinois jobs that pay $100,000 or more?question toggle

    Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.

  • Do Illinois job listings include remote or hybrid roles?question toggle

    Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.