Explore $100K+ Jobs in Illinois

Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.

Career Opportunities Across Illinois

Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.

Find a Role That Fits Your Experience

Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.

Advance Your Career in Illinois

Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.

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1,000+

Jobs in Illinois

Average Salary in USD

Average Salary: $117,836

Sort By: Relevance

$70K - $99K *

Launch your career by supporting software development and infrastructure modernization efforts within a dynamic team, enhancing services for Illinois residents while gaining valuable experience in app...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Drive successful project completion by overseeing installations across multiple teams, ensuring adherence to technical standards and optimizing resource deployment while maintaining strong client rela...

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$129K - $194K *

Join a team that's driving client acquisition and revenue growth through strategic relationships. Leverage your expertise in B2B sales to deliver tailored solutions and insights, while collaborating c...

6 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$215K - $235K *

Shape the future of enterprise solutions by serving as a trusted technical advisor, guiding strategic clients through complex architectural decisions and fostering long-term partnerships to unlock val...

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Engineer advanced protein design models and collaborate with experts to innovate in AI Drug Discovery, driving the development of candidate antibody therapeutics through deep learning and systems biol...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$102K - $170K *

Accelerate progress at transforming data solutions by building production-grade assets. Leverage your expertise in data engineering and business fluency to create trusted, reusable data products that...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $200K *

Shape the future of data solutions as a Database Support Engineer, driving customer success through onboarding, technical support, and collaboration with sales teams to enhance product adoption and op...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $251K *

Pioneer innovative technology strategies and architectural solutions across Agile teams, driving AI-enabled engineering transformation and ensuring scalable, secure, and maintainable solutions for ent...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$118K - $135K *

Engage customers and drive renewal success by managing a portfolio, reinforcing value, and leading negotiations. Collaborate cross-functionally to mitigate risks and ensure a positive customer experie...

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$68K - $102K *

Drive your career with a dynamic role in global benefits administration, ensuring compliance and enhancing employee wellness programs. Collaborate with vendors and support Total Rewards initiatives wh...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$115K - $130K *

Lead the charge in optimizing search channels for diverse clients, managing a global team while driving SEO, PPC, GEO, and AIO strategies. Ensure performance efficiency and deliver insightful reportin...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$112K - $188K *

Join us to lead inventory optimization initiatives that enhance customer solutions through advanced analytics and strategic planning, partnering with cross-functional teams to drive operational effici...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$71K - $94K *

Join a team that's dedicated to delivering compassionate care in a fast-paced medical environment. As a License Pending RN, you'll assess, plan, and implement patient care while collaborating with hea...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$112K - $188K *

Optimize your career by leveraging advanced analytics and modeling to enhance supply chain network design. Lead cross-functional projects, influence strategic decisions, and mentor team members in a h...

Reposted 6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$210K - $250K *

Innovate in AI-native primary care by leading a dynamic medical group. Manage physicians, enhance care delivery, and shape clinical programs while maintaining direct patient care involvement. Drive ex...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Lead the charge in managing IT projects for our enterprise payments ecosystem. Collaborate with technical teams to develop detailed project plans, ensuring successful execution and alignment with busi...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$94K - $118K *

Unlock your potential by managing a comprehensive benefits program, ensuring compliance, and enhancing employee experience. Collaborate with cross-functional teams to streamline operations and support...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$200K - $240K *

Pioneer the development of a new Professional Liability product, focusing on E&O and MPL. Lead underwriting strategy, drive profitable growth, and leverage technology to enhance client-centric process...

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$200K - $240K *

Transform the future of commercial insurance by leading the development of a new Professional Liability product. Drive strategy, build broker relationships, and ensure profitable growth while collabor...

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$130K - $133K *

Advance clinical research by leading site monitoring and management efforts. Ensure compliance with regulatory standards while overseeing study protocols and data integrity. Collaborate with teams to...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $118K *

Optimize patient care by guiding individuals through the cancer treatment journey. Collaborate with healthcare teams to ensure timely access to resources, education, and support, enhancing patient sat...

6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Lead treasury operations and investment strategies, ensuring compliance and optimizing cash flow. Collaborate with senior leadership to enhance financial planning and reporting, while managing a subst...

6 days ago

  •   8 - 10 years exp.  •   Transportation

$85K - $97K *

Join a dynamic team to manage billing processes, ensuring accuracy and compliance while collaborating with attorneys and clients. Drive efficiency in billing operations and enhance client service thro...

6 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$105K - $155K *

Join a team that's dedicated to safeguarding critical systems through expert security management. Leverage your RMF knowledge to ensure compliance, drive remediation, and maintain robust security post...

RemoteRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$190K - $315K *

Shape the future of visual design for an enterprise design system, leading the evolution of its visual language and guiding teams to create consistent, high-quality experiences across products and maj...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Illinois?question toggle

    Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.

  • Are there high-paying jobs outside Chicago?question toggle

    Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.

  • How can I find Illinois jobs that pay $100,000 or more?question toggle

    Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.

  • Do Illinois job listings include remote or hybrid roles?question toggle

    Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.