Explore $100K+ Jobs in Illinois

Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.

Career Opportunities Across Illinois

Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.

Find a Role That Fits Your Experience

Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.

Advance Your Career in Illinois

Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.

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1,000+

Jobs in Illinois

Average Salary in USD

Average Salary: $117,810

Sort By: Relevance

$125K - $140K *

Join us to lead systems and network administration for a critical military enterprise. You'll ensure operational excellence, manage outage responses, and maintain compliance with security regulations...

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $160K *

Unlock your potential as a Solution Architect, leading CRM design and integration for pharma and biotech. Drive innovation with Veeva CRM and Salesforce, ensuring seamless operations and client engage...

RemoteRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$216K - $243K *

Pioneer advancements in vaccine research and development, driving global immunization efforts. Collaborate across teams to ensure compliance and effective delivery of safe vaccines, enhancing public h...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $93K *

Grow your career with a dynamic Finance team as a Staff Accountant, supporting financial operations for R&D programs and USG contracts. Collaborate across departments to ensure accurate financial reco...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Lead the execution of clinical trials by monitoring site activities, ensuring compliance with regulations, and collaborating with teams to achieve study objectives. Play a key role in training site st...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate your career by leading Infor M3 ERP implementations. Drive project success through strategic planning, client management, and cross-functional collaboration while ensuring timely delivery and...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Optimize your career by providing critical analytical support for hardware and software installations across various platforms, ensuring compliance with regulations and enhancing operational efficienc...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Lead the charge in providing strategic oversight for enterprise information systems and cybersecurity operations, ensuring robust network defense and effective program management while collaborating w...

5 days ago

  •   11 - 15 years exp.  •   Information Technology

$95K - $115K *

Shape the future of configuration management by overseeing hardware inventory, documentation, and product releases. Collaborate with teams to implement effective change management processes throughout...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$200K - $250K *

Join a dynamic team as you lead and enhance special education services, guiding operations and strategic initiatives while collaborating with stakeholders to ensure effective program delivery and cont...

5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$160K - $200K *

Lead the charge in optimizing top-of-funnel marketing operations, driving measurable pipeline growth through strategic planning, data governance, and team leadership. Collaborate with cross-functional...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $175K *

Empower mission success by managing COMSEC lifecycle functions, ensuring the security and integrity of communication systems through expert oversight and compliance with national standards...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$135K - $160K *

Innovate and manage large-scale commercial programs, driving cross-functional alignment and revenue growth. Lead end-to-end program development, ensuring operational excellence and strategic execution...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$115K - $130K *

Champion secure and scalable cloud infrastructure in Azure and AWS. Drive lifecycle management of Windows Server and networking components while optimizing backend platforms and enhancing security mea...

5 days ago

  •   5 - 7 years exp.  •   Transportation

$145K - $160K *

Lead the transformation of our brokerage platform by driving automation, enhancing operational efficiency, and delivering measurable business outcomes through strategic partnerships and innovative tec...

5 days ago

  •   5 - 7 years exp.  •   Transportation

$80K - $81K *

Champion the delivery of therapeutic services for youth in a dynamic program. Oversee clinical staff, ensure compliance with standards, and enhance treatment effectiveness through collaboration and tr...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$79K - $83K *

Transform pediatric care by providing compassionate nursing support, ensuring patient safety, and collaborating with healthcare teams to deliver high-quality medical services in a dynamic clinical env...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$129K - $147K *

Champion innovative digital video strategies, focusing on CTV, while leading cross-functional teams to optimize campaign performance and drive growth in a dynamic advertising environment...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Media

$170K - $325K *

Elevate your career by securing and managing the transition to a hybrid-cloud infrastructure. Own identity management, cloud security, and developer tooling while leading incident response and threat...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Optimize energy solutions by leading technical projects, conducting site surveys, and collaborating with teams to deliver innovative, cost-effective strategies that enhance facility performance and su...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Energy & Utilities

$95K - $140K *

Lead impactful projects in water/wastewater systems, managing teams and client relationships to ensure quality delivery on time and within budget. Collaborate with experts to enhance operational servi...

5 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Join a team that's driving innovation in control systems for municipal and industrial projects. Leverage your expertise to tackle diverse challenges and enhance water and wastewater processes across t...

5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$93K *

Transform property management by optimizing financial performance, enhancing resident relations, and leading a dedicated team to achieve maximum occupancy and compliance with regulations...

5 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$100K - $150K *

Unlock potential by leading enterprise reporting strategies with Microsoft Fabric and Power BI. Drive data governance and analytics solutions, collaborating with stakeholders to transform data into ac...

5 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Shape and elevate business operations and account management, driving resource optimization and client satisfaction. Collaborate with leadership to enhance project delivery and expand client relations...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Illinois?question toggle

    Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.

  • Are there high-paying jobs outside Chicago?question toggle

    Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.

  • How can I find Illinois jobs that pay $100,000 or more?question toggle

    Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.

  • Do Illinois job listings include remote or hybrid roles?question toggle

    Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.