Discover vetted professional opportunities across Illinois with salaries of $100,000 or more. From Chicago’s expansive business community to growing industries throughout the state, Ladders helps experienced professionals find roles that match their skills, leadership experience, and career goals.
Search for high-paying jobs in Chicago, Naperville, Evanston, Springfield, and other Illinois communities. Opportunities may include on-site, hybrid, and remote positions, depending on the employer and role.
Illinois employers hire experienced talent across fields such as finance, technology, healthcare, consulting, manufacturing, and operations. Browse senior individual contributor, management, director, and executive openings, and review each listing for specific responsibilities and qualifications.
Use Ladders to explore vetted jobs with salaries of $100,000 or more. Compare opportunities, focus your search by location and specialty, and apply to roles that align with your experience and professional ambitions. Salary, work arrangement, and eligibility details vary by listing.
Average Salary: $117,810
Senior Security Engineering Manager
$151K - $226K *
Join a team that's dedicated to safeguarding technology environments by managing security policies, incident response, and threat investigations. Collaborate across IT and business functions to ensure...
3 days ago
Senior Manager, Payment Integrity - Vended Audit Programs
$107K - $199K *
Optimize cost recovery initiatives by managing vendor partnerships and streamlining processes. Collaborate with health plans to achieve budget targets and present actionable insights to senior managem...
Reposted 3 days ago
$123K - $186K *
Drive strategic initiatives by conducting data analysis and market research, collaborating with cross-functional teams, and crafting executive presentations to enhance operational effectiveness in a d...
3 days ago
$150K - $227K *
Advance strategic insights at a global scale by leading market research, quantitative analysis, and executive presentations. Collaborate with senior leadership to drive impactful decisions and shape t...
3 days ago
Director, Onsite Power Generation
$195K - $293K *
Join a team that's redefining onsite power generation strategy for global data centers. Lead cross-functional initiatives to enhance capacity, resiliency, and sustainability while driving innovative e...
Reposted 3 days ago
Manager, Health Informatics (Midwest)
$152K - $253K *
Elevate healthcare delivery by leveraging health information technology to enhance clinical workflows and patient care. Collaborate with health systems and cross-functional teams to implement effectiv...
Reposted 3 days ago
Manager, Health Informatics (Midwest)
$152K - $253K *
Lead strategic health informatics initiatives to enhance care delivery across diverse healthcare systems. Collaborate with stakeholders to align technology solutions with clinical workflows, ensuring...
Reposted 3 days ago
Manager, Health Informatics (Midwest)
$152K - $253K *
Shape the future of healthcare by leveraging health information technology to enhance patient care delivery. Collaborate with health systems and cross-functional teams to optimize clinical workflows a...
Reposted 3 days ago
Manager, Health Informatics (Midwest)
$152K - $253K *
Deliver impactful health informatics solutions by partnering with health systems to enhance care delivery, streamline workflows, and leverage technology for improved patient outcomes across multiple s...
Reposted 3 days ago
Manager, Health Informatics (Midwest)
$152K - $253K *
Champion health informatics initiatives to enhance care delivery across diverse healthcare systems. Collaborate with stakeholders to align technology solutions with clinical workflows, driving operati...
Reposted 3 days ago
Senior Director, Employer Program Management (P5), Lilly Employer
$166K - $244K *
Join a dynamic team to lead the Employer PMO, driving strategic program delivery and cross-functional alignment while enhancing operational efficiency and leveraging modern tools for impactful outcome...
3 days ago
$110K - $137K *
Join a team that's driving operational excellence in supply chain management. Lead cross-functional teams to optimize production processes, enhance quality, and achieve strategic business goals while...
3 days ago
Consulting Manager - Workday Benefits
$150K - $190K *
The Consulting Manager for Workday Benefits will lead teams in delivering complex implementations and system optimizations for Workday Benefits. This role requires expertise in benefits administration...
Reposted 3 days ago
Database and Application Support Engineer (Senior)
$110K - $130K *
Transform operations by supporting database availability and application performance. Collaborate with IT and development teams to diagnose issues, coordinate responses, and ensure seamless service re...
3 days ago
$80K - $95K *
Explore opportunities as a Network Engineer, providing hands-on support for data-center networking, software-defined solutions, and enterprise connectivity. Collaborate with teams to ensure secure, re...
3 days ago
Registered Nurse RN, Recovery Room (PACU)
$71K - $126K *
Champion patient care by utilizing nursing expertise and collaborating with interdisciplinary teams to develop and implement individualized care plans, ensuring safety and quality standards are met th...
3 days ago
Sr Engineer Software Validation
$101K - $152K *
Lead the development and execution of validation projects, ensuring compliance with customer and regulatory standards while managing multiple initiatives to enhance efficiency and quality in a fast-pa...
3 days ago
Manager, Clinical Data Management Study Lead
$114K - $187K *
Optimize clinical data management processes by leading teams and ensuring compliance with standards. Collaborate with stakeholders to enhance data quality and streamline operations across multiple com...
3 days ago
Business Development Manager - West Coast
$100K - $120K *
Drive growth by developing strategic partnerships in the travel industry. Leverage your expertise to identify opportunities, negotiate agreements, and support travel advisors and agencies in maximizin...
3 days ago
$80K - $95K *
Engage with mission-driven organizations to drive growth in housing solutions. Own the full sales lifecycle, from prospecting to closing, while expanding your portfolio and collaborating across teams...
3 days ago
Mortgage Loan Officer - 180 BPS - 104 Investors - Remote - W-2 or 1099
$150K - $500K *
Join a dynamic non-delegated lending platform that empowers you to control pricing, streamline operations, and maximize your earnings potential. Enjoy access to 60+ investors and robust tech support t...
Reposted 3 days ago
$100K - $150K *
Join a team that's transforming patient care through innovative AI solutions. As an AI Scientist, you'll design and deploy advanced multimodal models, collaborating with life sciences to enhance bioma...
3 days ago
Digital Consulting Manager, Oracle EPM FCCS/ARCS
$145K - $170K *
Elevate your career by leading cloud implementations and optimizing financial processes. Collaborate with teams to deliver end-to-end solutions within the Oracle EPM Cloud Suite, enhancing financial r...
3 days ago
Customer Success Manager (West Coast)
$175K - $200K *
Champion customer success by driving enterprise account value and adoption. Collaborate with stakeholders to ensure measurable outcomes, orchestrate resources, and uncover growth opportunities while f...
Reposted 3 days ago
Benefits Director--Health and Wellness
$50K - $243K *
Champion employee wellness by leading benefits strategy, overseeing program design, and ensuring alignment with business goals. Collaborate with stakeholders to enhance program effectiveness and drive...
3 days ago
What kinds of $100K+ jobs are available in Illinois?
Illinois listings may include senior and executive roles in areas such as finance, technology, healthcare, consulting, manufacturing, and operations. Available jobs and qualifications vary by employer.
Where can I find high-paying jobs in Illinois?
Explore opportunities in Chicago and throughout Illinois, including cities such as Naperville, Evanston, and Springfield. Listings may also include remote or hybrid roles.
Are Illinois jobs on Ladders vetted?
Ladders focuses on vetted professional jobs paying $100,000 or more. Check each listing for current salary information, responsibilities, and qualifications.
Do all Illinois jobs require working on-site?
No. Work arrangements depend on the employer and position. Review each job listing to see whether it is on-site, hybrid, or remote.