Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$110K - $130K *

Analyze technical sales opportunities from discovery to close, leveraging AI tools and client data to drive business cases. Collaborate with cross-functional teams to ensure seamless implementation an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $230K *

Manage strategic oncology product promotion and build relationships with key stakeholders. Drive performance goals, analyze market data, and ensure patient access to therapies while embodying corporat...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Support program operations by managing logistics, personnel processes, and documentation. Collaborate with leadership to enhance efficiency and responsiveness in a dynamic environment, ensuring accura...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$69K - $105K *

Elevate your research career by conducting impactful studies that enhance crisis services. Collaborate with experts to analyze data, develop tools, and contribute to vital evaluations that support the...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $205K *

Advance your career by driving growth in healthcare through impactful sales presentations and relationship management with hospital stakeholders. Collaborate across teams to optimize customer engageme...

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Champion efficiency in the revenue cycle as you lead a dedicated billing team. Drive performance improvements, oversee compliance, and identify revenue opportunities while cultivating a culture of exc...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$148K - $205K *

Take ownership of complex PBM data integrations, ensuring accurate claims and eligibility processing while leading cross-functional teams and managing delivery timelines and risks...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Shape the future of K-12 sales by leading a dynamic team of Account Executives. Drive performance through strategic planning, precise forecasting, and collaborative initiatives to achieve growth targe...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Engage in high-quality legal research to support law firm clients, focusing on intellectual property matters. Utilize advanced research tools to deliver accurate results and synthesize findings into a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Empower business success by collaborating with cross-functional teams to enhance operations, gather requirements, and implement IT solutions that align with strategic goals. Drive improvements in orde...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$224K - $326K *

Serve as a technical leader for large customers, guiding AI cloud strategies. Connect business priorities with scalable architecture while managing executive engagements and navigating complex decisio...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$165K - $228K *

Lead and empower a dynamic product management team, driving strategy, commercialization, and market engagement for innovative healthcare solutions while fostering collaboration across global business...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $115K *

Unlock potential by providing vital sales support and presentations, driving customer integration and product utilization, while conducting market research to enhance offerings. Collaborate closely wi...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in project management for global Metabolic/GLP-1 studies, ensuring outstanding delivery, budget management, and client satisfaction while guiding and mentoring project teams toward ope...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Manage the end-to-end onboarding of healthcare clients, leading cross-functional teams to ensure smooth transitions into coding and billing services while driving operational improvements and maintain...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Drive new business growth by owning the full sales cycle in the mid-market segment. Leverage your expertise in cybersecurity solutions to maximize revenue and collaborate cross-functionally to achieve...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Shape the future of technical proposals by collaborating with cross-functional teams to create compelling, scientifically accurate documents that meet client needs and drive business success in the li...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive network expansion by engaging providers and negotiating contracts to enhance Medicare services. Collaborate with a remote team to ensure network adequacy and build strong relationships with heal...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $230K *

Join a dynamic team as you lead engineering efforts to develop an AI Patient Engagement Agent, transforming clinical trials by automating patient interactions and enhancing operational efficiency for...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $180K *

Join a team that's driving growth in Life Sciences by managing key client relationships and delivering innovative solutions. You'll oversee the entire sales process, collaborating with experts to achi...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$255K - $310K *

Lead a high-performing team to execute market access strategies, optimize payer engagement, and enhance product positioning. Drive collaboration across stakeholders to ensure effective reimbursement a...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Join a dynamic strategy team to analyze oncology and specialty care initiatives, building models and providing insights that guide leadership decisions across various commercial segments...

RemoteRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Elevate animal care by providing clinical veterinary services for research animals, ensuring compliance and advancing husbandry programs. Collaborate with a dedicated team to support innovative biomed...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$134K - $184K *

Shape the future of customer success by leading a high-performing team, optimizing operations, and driving engagement and retention strategies to achieve key performance indicators and enhance client...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Drive strategic initiatives by developing KPI frameworks and operational dashboards, analyzing performance data, and collaborating across teams to enhance business outcomes and support informed decisi...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.