Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$97K - $145K *

Join a team that's dedicated to ensuring accurate coding and compliance for clinical services, leveraging your expertise to enhance revenue cycle management and contribute to optimal healthcare outcom...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$207K - $284K *

Elevate strategic partnerships in the healthcare diagnostics sector, driving innovative solutions and collaboration across teams. Lead high-impact initiatives that align customer needs with Siemens He...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$88K - $140K *

Shape the future of public service by leading technology consulting projects that enhance operational efficiency and strategic goals for state and local agencies, ensuring compliance and delivering im...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$175K - $195K *

Lead the charge in shaping enterprise data architecture, ensuring scalable, secure access across systems. Collaborate with engineering teams to deliver impactful data solutions that drive business val...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $120K *

Transform customer success by driving adoption and value realization for advisory teams. Collaborate cross-functionally to enhance workflows and deliver measurable outcomes, ensuring clients achieve e...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Reimagine client partnerships by managing complex relationships, driving performance, and leading recovery strategies. Collaborate with executives to ensure client success and identify growth opportun...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$350K - $430K *

Join a team that's at the forefront of ophthalmic genetic medicine development. Provide strategic oversight for clinical studies, ensuring patient safety and data integrity while collaborating with cr...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Innovate data-driven product strategies by leading informatics initiatives, ensuring rigorous testing and quality assessments while collaborating across teams to enhance client services and streamline...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$100K - $231K *

Advance your career by leading healthcare analytics initiatives that transform data into impactful insights, drive performance, and enhance decision-making across departments while fostering innovatio...

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Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$176K - $243K *

Unlock potential by leading strategic initiatives in cardiovascular imaging, driving adoption of advanced technologies, and fostering partnerships to enhance patient care and clinical outcomes across...

RemoteRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Healthcare

$90K - $110K *

Advance national account strategies and sales growth through effective relationship building and business planning. Collaborate across teams to negotiate contracts, leverage competitive advantages, an...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$137K - $185K *

Drive the execution of complex projects, ensuring alignment across global teams. Collaborate with stakeholders to manage risks, track progress, and deliver key medical strategies while fostering cross...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$92K - $110K *

Join a team that's dedicated to enhancing software quality and reliability. As a Business Analyst, you'll collaborate with cross-functional teams to gather requirements, facilitate Agile processes, an...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $95K *

Lead the charge in culinary excellence across multiple senior living communities, providing operational support, mentoring teams, and enhancing resident dining experiences while driving continuous imp...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$83K - $112K *

Partner with us to navigate complex patient cases and ensure seamless access to care. Utilize critical thinking and communication skills to manage authorizations and appeals, collaborating with divers...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$235K - $270K *

Unlock your potential as a strategic leader in field medical operations, driving scientific exchange and enhancing patient identification. Collaborate with key opinion leaders while building scalable...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$300K - $500K+*

Join a dynamic team as a senior leader driving portfolio performance across the eastern U.S. Oversee regional execution, manage a team of directors, and collaborate on national strategies to enhance b...

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Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$78K - $108K *

Empower our growth by managing and negotiating sales contracts, collaborating with cross-functional teams to ensure compliance and efficiency. Your expertise will drive impactful solutions in a dynami...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Consumer Technology

$130K - $160K *

Discover your potential as you drive enterprise sales in the CPG sector, building relationships with iconic brands. Leverage insights and solutions to develop strategies that enhance client success an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$150K - $279K *

Transform local government sales by proactively building relationships, generating pipeline, and driving revenue through innovative cloud solutions. Collaborate with a world-class sales team to exceed...

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3 weeks ago

  •   Less than 5 years exp.  •   Media

$160K - $195K *

Engage with healthcare payer clients to architect integrated solutions, driving revenue growth through strategic discovery, technical leadership, and value engineering. Collaborate across teams to del...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Healthcare

$215K - $240K *

Shape the future of commercial operations by leading strategy, workflows, and data integration. Collaborate with senior leaders to enhance brand performance and drive operational excellence across cro...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$104K - $143K *

Join a dynamic team to lead Quality Assurance efforts in Long-Term Services and Supports. Oversee compliance, collaborate with external partners, and drive operational excellence while ensuring adhere...

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1 week ago

  •   Less than 5 years exp.  •   Healthcare

$69K - $125K *

Join a dynamic team to oversee quality of care investigations and improvement initiatives, ensuring compliance with regulatory standards while enhancing patient outcomes and organizational efficiency...

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1 week ago

  •   5 - 7 years exp.  •   Healthcare

$121K - $161K *

Transform your career by leading the design and implementation of Veeva Vault RIM, ensuring optimal performance and compliance while collaborating with cross-functional teams to enhance user experienc...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.