Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$90K - $110K *

Accelerate program implementation and stakeholder engagement in pharmaceutical market access. Oversee daily operations, client relations, and staff management while ensuring adherence to budgets and p...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$169K - $282K *

Join a team that's redefining oncology clinical operations by leading a dynamic portfolio of studies. Drive excellence in delivery, manage complex projects, and mentor a talented team to ensure high-q...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$73K - $100K *

Elevate workforce planning by transforming data into impactful insights. Partner with leaders to build strategic forecasting tools and measure performance metrics, contributing to operational efficien...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$133K - $237K *

Contribute to patient safety by overseeing medical product surveillance, analyzing data, and ensuring compliance with regulations. Collaborate on risk management and support clinical studies to enhanc...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $190K *

Empower veterinary professionals by delivering expert dermatology advice and support, enhancing case management, and fostering strong relationships. Join a dynamic team committed to advancing veterina...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$77K - $106K *

Contribute to high-quality patient care by leading a clinical team, overseeing operations, and ensuring compliance. Empower clinicians through guidance and education while fostering independence in pa...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$175K *

Optimize revenue cycle management by leading a dynamic team to enhance processes, drive automation, and ensure compliance in a fast-paced telehealth environment. Collaborate with cross-functional team...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$138K - $191K *

Join a team that's redefining healthcare innovation by translating ideas into impactful solutions. Collaborate with senior executives to drive strategic initiatives and enhance population health throu...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $150K *

Join a team that's dedicated to enhancing patient care through comprehensive post-discharge support. As an Advanced Practice Provider, you'll manage complex cases, collaborate with interdisciplinary t...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$84K - $99K *

Join a dynamic team to evaluate and process medication prior authorization requests, ensuring compliance with clinical guidelines and regulatory standards while facilitating timely patient access to n...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$246K - $332K *

Transform healthcare by leading national strategic account management efforts. Drive partnerships with key institutions, enhance patient care, and foster cross-functional collaboration to achieve comm...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$103K - $192K *

Shape the future of healthcare reimbursement by leading analytics for payor contracting and out-of-network strategies. Collaborate with cross-functional teams to optimize financial outcomes and drive...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in expanding into new healthcare verticals by developing and executing go-to-market strategies, managing partnerships, and driving campaign performance. Collaborate with cross-function...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$198K - $258K *

Lead the charge in defining and governing architectural strategies for a secure and scalable software ecosystem across device and digital platforms, influencing cross-functional teams and senior stake...

United StatesRemote

Reposted 6 days ago

  •   11 - 15 years exp.  •   Healthcare

$120K - $140K *

Empower provider accounts post-launch by driving growth through strategic engagement, tailored training, and effective collaboration with internal teams. Cultivate relationships across diverse healthc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$250K - $275K *

Transform the future of drug development by leading Analytical Development for small molecules and oligonucleotides. Drive scientific strategy, build a high-performing team, and ensure regulatory read...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Drive strategic excellence in healthcare by leading business development, planning, and population health initiatives. Collaborate with teams to ensure that the mission and values guide MercyOne’s evo...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Engage with a talented team to drive growth and innovation in pharma sales. Own the sales cycle from strategic prospecting to closing high-impact deals, while developing key relationships that enhance...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$205K - $240K *

Shape the future of oncology as a Senior Medical Science Liaison, creating impactful scientific engagement within hematology and oncology that enhances patient care. Collaborate with KOLs and cross-fu...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead the charge in developing and overseeing scientific content across multiple therapeutic areas, ensuring high-quality contributions and strategic client interactions to drive growth and innovation...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$126K - $173K *

Drive impactful measurement strategies by leading cross-functional teams to define and deliver comprehensive reporting solutions that enhance decision-making and optimize business outcomes across the...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$86K - $116K *

Champion data-driven emergency response initiatives by leading analytics, ensuring quality assurance, and collaborating with global teams to enhance decision-making and program effectiveness in infect...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$90K - $100K *

Transform project management by leading client-sponsored trials, coordinating multidisciplinary teams, and ensuring timely delivery of objectives while fostering collaboration and communication across...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$180K - $200K *

Champion commercial manufacturing excellence by leading technical operations, ensuring on-time delivery of drug products and APIs, and collaborating with regulatory teams to meet compliance and perfor...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Explore a leadership role in nursing, driving operational excellence and patient care. Collaborate with healthcare teams to enhance departmental performance, ensuring compliance and fostering a cultur...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.