Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$150K - $180K *

Innovate the future of architectural strategy by leading technical direction, fostering collaboration across teams, and driving scalable solutions that align with business goals while mentoring senior...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$129K - $231K *

Reimagine drug discovery as you lead molecular pharmacology efforts in neuroscience. Collaborate across teams to develop strategies, interpret data, and advance innovative therapies for sleep-wake dis...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$96K - $144K *

Take ownership of contract management by drafting, negotiating, and administering agreements with key customers. Collaborate with cross-functional teams to ensure compliance and operational efficiency...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$100K - $122K *

Unlock your potential as you lead financial planning, analytics, and strategic initiatives. Collaborate closely with executives to drive performance improvements and optimize resource allocation, fost...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Unlock potential by driving BioPharma partnership success through innovative liquid biopsy solutions, enhancing clinical trial designs, and fostering key relationships in oncology precision medicine...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$246K - $332K *

Shape the future of health economics and outcomes research by leading strategic initiatives across the nephrology portfolio, ensuring high-quality evidence generation and collaboration with cross-func...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$205K - $380K *

Accelerate progress at enterprise sales by driving strategic growth initiatives, building relationships with healthcare leaders, and leading complex sales pursuits to enhance market presence and custo...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$193K - $262K *

Champion the sales force's success by leading a dynamic team focused on optimizing field effectiveness and operational efficiency, driving excellence in performance and insights...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$89K - $121K *

Shape the future of customer engagement by optimizing Genesys Cloud access management. Collaborate with cross-functional teams to enhance security, streamline user provisioning, and ensure compliance...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $150K *

Transform customer experiences by leading a high-performing team, driving retention and growth strategies, and leveraging AI to enhance service delivery. Be the voice of the customer while collaborati...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$80K - $90K *

Advance quality assurance initiatives and optimize workflows in a remote healthcare contact center. Collaborate cross-functionally to enhance compliance, improve patient outcomes, and drive continuous...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$117K - $161K *

Drive impactful clinical intelligence initiatives by analyzing AI opportunities, conducting feasibility studies, and collaborating with cross-functional teams to enhance patient care and operational e...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $216K *

Lead complex healthcare data initiatives by managing teams, translating business needs into technical solutions, and ensuring data quality and integration. Collaborate with stakeholders to drive analy...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$225K - $265K *

Transform healthcare interoperability by leading product strategy and market growth. Leverage deep industry insights to enhance payer-provider collaboration, drive operational excellence, and oversee...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Unlock potential by guiding global regulatory strategies for innovative AI/ML healthcare solutions. Collaborate cross-functionally to navigate complex regulations while balancing innovation and patien...

United StatesRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$180K - $220K *

Lead the evaluation of outpatient referrals and inpatient admissions for medical necessity, utilizing guidelines and criteria to ensure quality care. Collaborate with providers and mentor UM nurses to...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$71K - $97K *

Transform patient care by guiding transitions and ensuring optimal service continuity. Leverage your nursing expertise to navigate healthcare options and advocate for patients in need of post-acute se...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$105K - $140K *

Transform your career by leading government sales efforts in a high-growth environment. Leverage your expertise to build relationships, create pipelines, and drive revenue for a cutting-edge product i...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $120K *

Advance your career by ensuring safe medication practices and enhancing patient care. Collaborate with healthcare professionals to review prescriptions, resolve drug-related issues, and provide except...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Join a team that's redefining oncology care by overseeing clinical standards, evaluating therapies, and engaging with providers. You'll play a key role in shaping patient eligibility and treatment pro...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $215K *

Unlock potential by leading the development of a virtual engagement team to enhance outreach to healthcare professionals, ensuring effective collaboration with field sales and marketing for optimal im...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$111K - $167K *

Join a dynamic team as a strategic analytics partner, driving insights and performance improvements across revenue cycle operations. Collaborate with leaders to define KPIs, analyze data, and create i...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$132K - $170K *

Unlock client growth opportunities through strategic relationships, driving value in a fast-paced B2B sales environment. Collaborate with C-Level Executives across diverse sectors to ensure client sat...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$101K - $140K *

Join a dynamic team to drive client growth and retention by building trust-based relationships with C-Level Executives, ensuring they maximize value from services while identifying new opportunities f...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$125K - $150K *

Pioneer in radiology innovation by enhancing clinical value and technology. Join a forward-thinking team that prioritizes high-quality patient care while driving improvements in service and operationa...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.