Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Senior Director, Observational Research, CPSO
$204K - $276K *
Lead the charge in global observational research, driving clinical operational strategy and execution. Collaborate with cross-functional teams to ensure quality and efficiency in evidence generation t...
Today
Senior Consultant - Grants Lifecyle Process Improvement
$98K - $163K *
Optimize federal grants management operations by assessing processes, identifying inefficiencies, and delivering actionable recommendations. Collaborate with stakeholders to enhance program outcomes a...
3 weeks ago
Associate Director, Regional Marketing (Midwest Region)
$120K - $145K *
Join a team that's driving regional marketing initiatives in hematology and oncology. Engage with key thought leaders, execute strategic plans, and leverage local opportunities to enhance brand presen...
3 weeks ago
$107K - $145K *
Drive growth by identifying and securing new business opportunities in risk management and medical education. Collaborate with teams to develop proposals, manage sales pipelines, and ensure alignment...
Reposted yesterday
Clinical Application Specialist, Monitoring
$90K *
Elevate your career by providing clinical support and training for patient monitoring systems. Lead implementation teams, ensure customer satisfaction, and maintain clinical expertise while managing t...
Reposted 2 days ago
Senior Quality Operations Specialist, CAP & Monitoring
$74K - $98K *
Elevate quality operations by leading corrective action plans (CAPs) for regulatory compliance. Collaborate with cross-functional teams to drive accountability, resolve barriers, and ensure sustained...
3 weeks ago
Clinical Marketing Manager, Patient Monitoring
$130K - $143K *
Optimize your career by developing and executing clinical marketing strategies that enhance customer engagement and drive adoption of innovative patient monitoring solutions. Collaborate with cross-fu...
Reposted 2 days ago
Software Engineer/Sr Software Engineer
$120K - $170K *
Develop and enhance Python services for pharmacy claims processing. Collaborate across teams to deliver high-quality solutions while gaining expertise in the pharmacy benefits domain. Embrace a hybrid...
3 weeks ago
Principal, Cloud Solutions Architect
$208K - $235K *
Innovate and lead the development of scalable cloud solutions, ensuring high engineering standards and strategic architecture. Collaborate with cross-functional teams to translate business needs into...
4 weeks ago
$138K - $186K *
Unlock your potential as a principal technical leader for enterprise Unix and Linux platforms, driving architecture, automation, and lifecycle management to deliver resilient infrastructure for critic...
3 weeks ago
Consultant, Cyber Architecture
$110K - $130K *
Champion your career by leading security engagements, assessing architectures, and enhancing compliance. Collaborate with top professionals to identify risks and implement best practices, ensuring rob...
Today
Director, Global Drug Safety & Pharmacovigilance Operations
$150K - $180K *
Advance global drug safety initiatives by leading pharmacovigilance activities, ensuring compliance with regulations, and collaborating with cross-functional teams to enhance product safety and operat...
2 days ago
Senior Technical Product Manager - Insurance Products & Benefits
$104K - $143K *
Lead the charge in developing and delivering innovative technology solutions for managing Medicare/Medicaid plans. Collaborate with cross-functional teams to drive product vision, strategy, and execut...
Reposted 3 days ago
Patient Strategy & Experience, Customer Experience Lead
$240K - $330K *
Lead the development of patient experience strategies, integrating insights and design thinking to enhance patient journeys across therapeutic areas. Collaborate with cross-functional teams to drive i...
4 days ago
Senior Director Compliance Monitoring & Surveillance
$144K - $210K *
Drive compliance excellence by leading a team focused on identifying and addressing control gaps and violations across financial services, ensuring adherence to regulatory standards while enhancing su...
Reposted today
$81K - $110K *
Lead the transformation of patient care by enhancing utilization review processes, ensuring quality documentation, and collaborating with healthcare teams to optimize clinical outcomes and financial p...
3 days ago
HSOM-Open Rank-Surgical Oncology (Chief) Surgery
$250K - $300K *
Join a team that's at the forefront of surgical oncology, leading a dynamic division. Oversee patient care, research initiatives, and faculty development while contributing to a collaborative environm...
Reposted 1 week ago
Sr Area Business Director, West
$160K - $190K *
Lead the charge in driving growth by managing a high-performing sales team, collaborating across functions, and executing strategic initiatives to enhance commercial success in the Hematology sector...
Yesterday
Medical Science Liaison, Central US (Multiple Territories)
$155K - $175K *
Empower healthcare professionals by delivering scientific insights and fostering relationships. Drive prelaunch and launch strategies in a dynamic environment, ensuring clinical readiness and impactfu...
2 weeks ago
Clinical Applications Support Specialist
$90K - $105K *
Optimize healthcare support by serving as the primary contact for clinical application issues. Collaborate with clinicians and IT teams to troubleshoot, educate, and resolve technical challenges, ensu...
4 weeks ago
Clinical Project Research Manager - EDS/RWE/NIS
$100K - $120K *
Elevate project outcomes by leading cross-functional teams to deliver clinical research projects on time and within budget, ensuring compliance with regulatory standards and client expectations while...
Reposted 2 days ago
Senior Director, Head of Research & Early Development
$228K - $342K *
Empower your career by leading strategic project management initiatives across early drug development. Drive process optimization, cultivate high-performing teams, and collaborate with executives to a...
Yesterday
Director, Neurology - Thought Leader Liaison (NORTHEAST)
$245K - $265K *
Build impactful partnerships with Medical Experts to enhance neurology care. Drive strategic insights and collaboration across teams, influencing marketing and education initiatives while engaging wit...
2 weeks ago
$110K - $130K *
Unlock potential by owning the end-to-end product surface, driving discovery, design, and migration while collaborating closely with users to solve real market problems in a dynamic healthcare environ...
3 weeks ago
Director, Analytical Development and Quality Control
$192K - $235K *
Lead analytical development and quality control for sterile parenteral products, ensuring regulatory compliance and successful product launches. Collaborate cross-functionally to establish strategies...
1 week ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.