Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$80K - $95K *

Elevate your career by managing coding operations, ensuring accuracy and compliance across healthcare settings. Lead educational initiatives for staff, optimize workflows, and drive improvements in co...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $140K *

Join a team that's driving project success by leading technical initiatives, resolving complex challenges, and aligning outcomes with client objectives. Your expertise will enhance profitability and o...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $160K *

Oversee the operational planning and execution of clinical trials, ensuring compliance with regulatory standards while managing cross-functional teams to meet project timelines, budgets, and quality o...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Lead manufacturing operations by managing teams to enhance efficiency, safety, and product quality. Align departmental goals with business needs while ensuring compliance with industry standards and o...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$239K - $358K *

Join a team that's committed to maximizing growth in pharmaceutical accounts through strategic planning and relationship building, focusing on data-driven solutions and real-world evidence to foster l...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $120K *

Accelerate progress at the intersection of media and healthcare by leading integrated planning and strategy for pharmaceutical clients. Drive impactful engagement initiatives while mentoring a talente...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$176K - $220K *

Lead the charge in driving sustainable revenue growth by managing a high-performing team of Account Executives focused on acquiring new clients in the financial sector, ensuring effective sales execut...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$176K - $220K *

Lead the charge in developing high-performing partnerships and teams to drive growth in North America's aftermarket channel, collaborating across functions to enhance partner performance and customer...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$84K - $126K *

Empower decision-making by transforming data into intuitive models. Collaborate with stakeholders to ensure metrics are clear and trusted, while optimizing data for analytics and reporting across the...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Join a team that's dedicated to delivering exceptional client service and operational excellence. As a Program Manager, you'll oversee program execution, account management, and financial oversight wh...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$232K - $290K *

Lead the charge in optimizing workforce operations and analytics for multi-condition health care services. Develop strategies for capacity planning, staffing, and analytics to drive efficiency and sup...

United StatesRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$134K - $306K *

Elevate customer engagement by developing and executing strategic study plans, leading cross-functional teams, and ensuring successful project delivery in the rare disease therapeutic area...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$153K - $200K *

Lead the charge in shaping corporate communications and brand strategy, enhancing market presence and credibility. Collaborate with executives and teams to amplify messaging and drive impactful initia...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$140K - $190K *

Shape the future of healthcare revenue cycle performance by leading transformative initiatives, optimizing client success, and fostering innovation across multiple healthcare partnerships. Drive measu...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$103K - $161K *

Drive strategic growth by establishing and nurturing key partnerships with Enterprise Claims carriers, ensuring service excellence and collaboration across internal teams to enhance business outcomes...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$91K - $145K *

Shape the future of data solutions by leading complex pharmacy claims and physician-level data integrations. Collaborate with cross-functional teams to deliver high-quality, scalable solutions that me...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive data integrity and operational excellence by resolving complex payer data issues, collaborating across teams, and enhancing data quality for value-based care initiatives. Play a key role in opti...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Drive strategic growth and business development for National Accounts in Urology and Oncology, optimizing resources and leading negotiations to enhance healthcare outcomes through innovative diagnosti...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$144K - $245K *

Lead the design and execution of workforce development programs, ensuring compliance and timely deliverables. Collaborate across teams and stakeholders to create scalable systems that enhance healthca...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$107K - $150K *

Shape the future of our enterprise data platform by leading product strategy, defining capabilities, and ensuring alignment across business and technology teams to deliver scalable, secure, and truste...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$223K - $233K *

Deliver strategic leadership in biologics process development, overseeing outsourced manufacturing and ensuring alignment with corporate goals while driving technical excellence in late-stage developm...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$182K - $247K *

Drive innovative clinical operations to enhance member care and outcomes. Collaborate across teams to implement strategies, optimize processes, and scale programs, ensuring seamless coordination and e...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Drive impactful change by optimizing product operations through collaborative process design, ensuring alignment and efficiency while fostering innovation and simplification across complex product tea...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$149K - $224K *

Shape the future of data governance by leading the design and implementation of enterprise platforms that ensure data integrity, quality, and compliance across the organization, while collaborating wi...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$227K - $341K *

Lead the strategic development and continuous improvement of clinical programs, focusing on optimizing patient care across the continuum. Oversee a multidisciplinary team to enhance outcomes, reduce h...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.