Director, Quality Operations Jobs

Explore Director, Quality Operations roles for experienced leaders who build reliable quality systems, guide compliance, and improve operational performance. These directors help organizations deliver products and services that meet customer expectations and applicable regulatory requirements. Find vetted professional opportunities paying $100,000 or more on Ladders.

What Does a Director of Quality Operations Do?

A Director of Quality Operations sets quality strategy and oversees the processes, teams, and systems that support consistent outcomes. Responsibilities may include developing quality management systems, monitoring performance metrics, leading internal and external audits, addressing nonconformances, and coordinating corrective and preventive actions. The role often partners with operations, engineering, supply chain, product, and regulatory teams.

Skills and Qualifications

Employers commonly seek substantial experience in quality, manufacturing, operations, or a related field, along with a record of leading teams and cross-functional initiatives. Helpful strengths include knowledge of quality standards and regulatory requirements, risk management, root-cause analysis, audit leadership, process improvement, and data-driven decision-making. Depending on the industry, relevant credentials or specialized expertise may also be preferred.

Industries and Career Opportunities

Director-level quality operations roles can be found across industries such as healthcare, pharmaceuticals, biotechnology, medical devices, manufacturing, technology, and consumer products. The scope varies by organization: some positions focus on a single facility or business unit, while others oversee quality programs across multiple sites or regions. Browse current openings to compare responsibilities, industries, and leadership scope.

Find Director, Quality Operations Jobs on Ladders

Ladders features vetted professional jobs with salaries of $100,000 or more. Search Director, Quality Operations openings to identify opportunities that align with your experience, preferred industry, and career goals.

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$135K - $160K *

Join a team that's redefining People Operations by leading strategic initiatives in benefits, payroll, and automation. Drive impactful change while managing a high-performing team and collaborating ac...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$223K - $233K *

Deliver strategic leadership in biologics process development, overseeing outsourced manufacturing and ensuring alignment with corporate goals while driving technical excellence in late-stage developm...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the quality assurance efforts for commissioning, qualification, and validation across multiple manufacturing sites, ensuring compliance with cGMP standards while collaborating with cross-function...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$170K - $195K *

Lead the charge in global regulatory submissions, managing U.S. INDs and ex-U.S. CTAs. Collaborate cross-functionally to develop strategies, ensure compliance, and drive timely approvals in a fast-pac...

San Francisco, CARemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$112K - $223K *

Lead global pharmacovigilance initiatives, ensuring compliance and operational excellence while guiding teams through complex safety reporting challenges across diverse therapeutic areas and trial pha...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Elevate clinical operations by leading daily workflows, managing teams, and spearheading impactful projects. Drive improvement and efficiency in healthcare delivery while fostering collaboration acros...

New York, NYRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$194K - $291K *

Lead the strategic and operational execution of companion diagnostic projects in oncology, ensuring alignment with clinical development and regulatory standards while driving cross-functional collabor...

Princeton, NJRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $135K *

Champion a global HSEQ strategy, fostering compliance and quality across operational regions while developing a proactive safety culture and optimizing customer service delivery in the solar and stora...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$165K - $180K *

Oversee and optimize US regional clinical trials, ensuring execution and compliance. Collaborate with cross-functional teams and manage vendor relationships while driving process improvements in a fas...

Houston, TXRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$280K - $300K *

Shape the future of clinical supply management by leading strategy and execution for transformative therapies. Collaborate cross-functionally to ensure timely delivery of investigational products, whi...

Boston, MARemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$225K - $275K *

Optimize quality assurance processes to ensure compliance with regulatory standards and drive improvements across all operations. Lead a talented team to establish and maintain an effective Quality Ma...

United StatesRemote

Reposted 2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Oversee the operational planning and execution of clinical trials, ensuring compliance with regulatory standards while managing cross-functional teams to meet project timelines, budgets, and quality o...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$203K - $228K *

Join a dynamic team to lead strategic manufacturing operations, integrating technical and business insights to drive successful commercialization and lifecycle management of biologics and cell therapi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Partner with us to build a scalable sales operations framework across the Americas, enhancing forecast accuracy and pipeline management while fostering strong relationships with field leadership and d...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$135K - $160K *

Lead the charge in engineering excellence by managing complex projects, mentoring teams, and driving innovative technology implementations. Ensure sustainable operations while aligning with business o...

Georgia, USRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Transportation

$90K - $110K *

Unlock potential by building and optimizing the global marketing operations infrastructure. Manage CRM systems, oversee campaign execution, and drive data integrity to enhance performance across sales...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Champion quality assurance initiatives by managing site audits, enhancing compliance, and fostering relationships with investigative teams. Utilize risk-based approaches to monitor quality indicators...

Tennessee, USRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$112K - $193K *

Drive the optimization and governance of clinical supplemental data sources, ensuring compliance with HEDIS and CMS standards. Collaborate across teams to enhance data quality and support strategic in...

Minnetonka, MNRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $178K *

Drive excellence in pharmacovigilance by leading teams and ensuring compliance with global safety regulations. Influence patient safety initiatives while managing project delivery across diverse clini...

Durham, NCRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$90K - $178K *

Drive excellence in pharmacovigilance by leading teams and projects, ensuring compliance and safety across clinical trials. Leverage scientific expertise and operational oversight to mentor profession...

North Carolina, USRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Transform your career by leading cross-functional teams to drive drug development strategies. Collaborate with key stakeholders to ensure successful execution of integrated plans, manage risks, and de...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$107K - $199K *

Transform the healthcare landscape by leading digital quality measurement initiatives. Drive process improvement efforts and enhance clinical data reporting strategies while collaborating with cross-f...

Missouri, USRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$182K - $198K *

Build and lead a robust Service Management Office to enhance IT operations, ensuring effective governance, accountability, and continuous improvement across a complex 24x7 environment, while fostering...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$171K - $202K *

Drive the creation and oversight of a risk framework that balances growth with security. Partner with cross-functional teams to implement risk strategies operationally, while conveying insights to exe...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $110K *

Contribute to the success of pharmaceutical programs by managing client relationships, overseeing daily operations, and driving performance. Collaborate cross-functionally to ensure program execution...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Quality Operations do?question toggle

    A Director of Quality Operations leads quality strategy, systems, and teams to help ensure processes and outputs meet company standards, customer expectations, and applicable regulations. Duties may include audits, quality metrics, risk management, and corrective actions.

  • What qualifications are commonly required for Director, Quality Operations jobs?question toggle

    Requirements vary, but employers often look for extensive quality or operations experience, people and program leadership, and knowledge of quality systems, audits, regulatory expectations, and continuous improvement.

  • Which industries hire Directors of Quality Operations?question toggle

    These leaders work in a range of sectors, including manufacturing, healthcare, pharmaceuticals, biotechnology, medical devices, technology, and consumer products.

  • How much do Director, Quality Operations jobs pay?question toggle

    Compensation depends on factors such as industry, location, experience, and scope of responsibility. Ladders focuses on vetted professional jobs paying $100,000 or more.

  • Where can I find Director, Quality Operations jobs paying $100,000 or more?question toggle

    Search Ladders for Director, Quality Operations openings and review vetted professional opportunities with salaries of $100,000 or more.