Director, Quality Operations Jobs

Explore Director, Quality Operations jobs for experienced leaders who build reliable quality systems and help organizations deliver safe, compliant, high-quality products and services. Ladders features vetted professional opportunities paying $100,000 or more, including roles across manufacturing, healthcare, pharmaceuticals, biotechnology, medical devices, and other regulated industries.

What Does a Director of Quality Operations Do?

A Director of Quality Operations leads the processes, teams, and systems that support consistent quality across an organization. Responsibilities may include setting quality strategy, overseeing quality management systems, ensuring regulatory compliance, preparing for audits and inspections, investigating issues, and guiding corrective and preventive actions. Directors also work across departments to reduce operational risk and improve performance.

Skills and Experience Employers Seek

Employers commonly look for leadership experience in quality assurance or quality operations, knowledge of relevant industry regulations and standards, and a record of improving processes and outcomes. Useful strengths include audit readiness, risk management, root-cause analysis, change control, data-driven decision-making, and clear communication. Depending on the industry, employers may prefer experience with standards such as ISO requirements or regulations governing pharmaceutical, medical-device, or healthcare operations.

Career Opportunities in Quality Operations

Director-level opportunities can vary by company size, product portfolio, and regulatory environment. Some roles focus on a single site or business unit, while others oversee quality across multiple facilities or regions. Experienced directors may progress to vice president of quality, chief quality officer, or broader operations and compliance leadership roles.

Find Director, Quality Operations Jobs on Ladders

Browse Director, Quality Operations openings on Ladders to find vetted professional roles with salaries of $100,000 or more. Review each listing for its responsibilities, qualifications, location, and compensation details, and apply to opportunities that match your leadership experience and career goals.

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$150K - $180K *

Optimize quality operations for large-scale data pipelines, ensuring high standards and consistency across diverse datasets. Lead a team to enhance efficiency and reliability in audio data processing...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$200K - $270K *

Lead the development and execution of GxP quality systems, ensuring compliance and oversight for clinical and CMC quality. Drive vendor qualification, audits, and training while fostering a culture of...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $228K *

Drive enterprise Quality and Regulatory governance for U.S. operations, ensuring compliance with FDA regulations and overseeing manufacturing quality in the therapeutic radiopharmaceutical sector whil...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Join a team that's dedicated to establishing a robust Quality Management System, ensuring compliance and excellence in global clinical development and commercialization. Lead quality initiatives and f...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Drive quality excellence in clinical programs by overseeing compliance, risk management, and vendor oversight. Collaborate cross-functionally to ensure adherence to GCP regulations and lead inspection...

San Francisco, CARemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $150K *

Join us to lead strategic operations and enhance customer experience across the Last Mile network. Drive performance improvements, manage claims, and implement scalable solutions while collaborating w...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$130K - $160K *

Lead quality operations to ensure data accuracy and compliance in healthcare. Drive improvements through audits, data analysis, and technology integration, fostering a culture of excellence across tea...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$117K - $189K *

Join a team that's shaping the future of pharmaceutical quality by leading compliance initiatives and building a robust Quality Management System to support innovative therapies in a dynamic, collabor...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$154K - $208K *

Shape the future of quality operations by leading teams to enhance product excellence and consumer satisfaction across global markets, driving continuous improvement and strategic initiatives in a dyn...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$245K - $286K *

Elevate clinical quality assurance through strategic leadership and oversight of global trials, ensuring compliance with GCP regulations. Drive quality culture and inspection readiness while mentoring...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $258K *

Elevate your career by leading strategic initiatives in Medical and Scientific Affairs. Drive portfolio governance, enhance operational excellence, and foster cross-functional collaboration to deliver...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$104K - $145K *

Lead the charge in developing a robust quality control program, managing a team to enhance operational processes, mitigate risks, and ensure compliance across lending operations while leveraging autom...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$142K - $224K *

Lead quality engineering and assurance for medical devices, ensuring compliance with regulations and industry standards while collaborating across teams to achieve quality goals and support product de...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Elevate operational excellence and quality management by leading process improvements, ensuring compliance, and fostering a patient-first culture. Oversee a dedicated team to enhance quality systems a...

Ontario, CARemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in ensuring quality assurance for transport and packaging validation, collaborating with cross-functional teams to uphold compliance and readiness for commercial launch while managing...

New York, USRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform quality assurance by leading a dedicated team, ensuring compliance, and managing complex client projects. Drive excellence in drug importation and quality documentation while fostering stron...

Ontario, CARemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Empower your career by leading our Quality Management System and cultivating a quality-centric culture. Collaborate across teams to define standards, manage audits, and support regulatory compliance a...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$172K - $232K *

Lead the charge in advancing global quality initiatives, ensuring product excellence, and fostering expertise in quality risk management while collaborating across teams to enhance compliance and oper...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$176K - $204K *

Join a team that's dedicated to enhancing quality assurance in cell therapy. You will oversee compliance activities across vendors, strengthen quality systems, and drive a culture of continuous improv...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $195K *

Empower quality assurance excellence by leading GMP oversight for contract manufacturing and validation projects, ensuring compliance and collaboration across technical operations to support drug deve...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$172K - $210K *

Transform regulatory operations by leading submission strategies, managing systems, and ensuring compliance across portfolios while collaborating with cross-functional teams for successful outcomes...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$159K - $211K *

Join us in transforming quality operations by leading a robust PACE quality program, ensuring compliance and care excellence while collaborating cross-functionally to enhance participant outcomes and...

California, USRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$149K - $173K *

Lead quality and food safety initiatives across North America, ensuring compliance and audit readiness. Drive continuous improvement and operational excellence through technical expertise and collabor...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Food & Beverages

$110K - $130K *

Manage clinical trial operations, ensuring compliance and performance across protocols. Oversee submissions, budgets, and team coordination while collaborating with internal and external stakeholders...

Quebec, CARemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$126K - $145K *

Join a team that's dedicated to ensuring compliance and quality in GxP computer systems. Oversee validation and lifecycle management across clinical, quality, and manufacturing environments while coll...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Quality Operations do?question toggle

    A Director of Quality Operations leads quality teams and systems, supports regulatory compliance, manages audits and investigations, and drives improvements that help ensure consistent products or services.

  • What qualifications are commonly required for Director, Quality Operations jobs?question toggle

    Requirements vary by employer and industry, but commonly include relevant leadership experience in quality or operations, knowledge of applicable regulations and standards, and strengths in audits, risk management, process improvement, and corrective actions.

  • Which industries hire Directors of Quality Operations?question toggle

    Employers hire for these roles in fields such as manufacturing, pharmaceuticals, biotechnology, medical devices, healthcare, and other industries where quality systems and regulatory compliance are important.

  • What is the typical salary for a Director of Quality Operations?question toggle

    Compensation varies based on industry, location, company size, and experience. Ladders focuses on vetted professional jobs paying $100,000 or more; check individual listings for the available compensation information.

  • How can I find Director, Quality Operations jobs paying $100,000 or more?question toggle

    Browse Director, Quality Operations listings on Ladders and review each role’s salary information, responsibilities, qualifications, and location to identify opportunities that fit your experience.