Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Business Project Manager - Global Client Services
$105K - $150K *
Lead the charge in executive support and strategic sales initiatives, managing schedules, communications, and events for the EVP of Global Client Services. Drive efficiency and stakeholder engagement...
Yesterday
$80K - $121K *
Champion legal operations excellence by driving process improvements, metrics establishment, and AI integration to enhance workflow efficiencies and support the Legal team in dynamic, fast-paced envir...
Reposted 3 weeks ago
Senior Project Manager, Marketing PMO
$110K - $130K *
Lead complex, cross-functional marketing initiatives from planning to execution, driving accountability and collaboration across teams while enhancing project management processes and methodologies fo...
1 week ago
Assistant Project Manager (MEP Design)
$83K - $104K *
Collaborate effectively with project teams to manage workflows, deliverables, and communications, ensuring high-quality execution across all project phases in commercial and critical environments...
Reposted 4 weeks ago
Director, PDM Planning & Operations
$125K - $150K *
Deliver strategic leadership for a centralized partner data management system, ensuring alignment with business priorities and enhancing user experience. Collaborate with cross-functional teams to dri...
2 weeks ago
$147K - $220K *
Drive the success of clinical study projects by managing timelines, budgets, and quality standards. Collaborate with teams and clients to ensure project objectives are met while fostering a culture of...
2 weeks ago
$147K - $220K *
Optimize project delivery by leading clinical study initiatives, ensuring quality, budget, and timelines are met. Collaborate with teams and clients to drive success in complex global trials while man...
2 weeks ago
$150K - $180K *
Shape the future of enterprise-scale cybersecurity by leading vulnerability management initiatives. Drive program strategy, enhance client relationships, and mentor teams to achieve measurable risk re...
Reposted 2 weeks ago
Project Manager - Power Solutions
$165K - $185K *
Grow your career with us by leading complex electrical power solutions projects. Collaborate with diverse teams to deliver innovative solutions for mission-critical facilities, ensuring projects meet...
2 weeks ago
Director, Project Management Talent & Delivery Excellence - EDS
$135K - $160K *
Grow your career with a senior leadership role driving a high-performing project management team, ensuring successful execution of clinical studies while managing resources, performance, and client sa...
Reposted 2 days ago
$80K - $95K *
Help us deliver innovative environmental design projects by leading cross-functional teams through all phases from planning to implementation, ensuring alignment, managing risks, and achieving client...
4 weeks ago
$110K - $125K *
Drive the Reuse function within the Product Lifecycle team, ensuring efficient operations, stakeholder communication, and process consistency to support the mission of serving Veterans. Lead a team fo...
1 week ago
Senior Project Manager, M&A & Large Projects
$150K - $250K *
Lead the charge in managing complex M&A projects and cross-functional initiatives, driving execution from planning to completion while fostering collaboration and alignment among diverse stakeholders...
3 weeks ago
$95K - $149K *
Lead the charge in delivering complex product development projects by managing cross-functional teams, ensuring customer satisfaction, and driving operational excellence from initiation to delivery in...
2 weeks ago
Project Manager, Strategic Projects
$97K - $109K *
Unlock potential by driving project execution and fostering collaboration across teams. Manage risks, enhance visibility, and support multiple initiatives to ensure timely delivery and continuous impr...
2 days ago
Implementation Project Manager
$90K - $110K *
Champion client success by leading complex implementations, managing risks, and ensuring operational readiness. Collaborate with executive stakeholders to deliver projects on time while maintaining hi...
Reposted 3 days ago
$83K - $118K *
Unlock your potential by leading complex IT/SaaS projects, driving execution, and enhancing business processes. Collaborate with diverse teams to ensure project success while utilizing Agile methodolo...
2 weeks ago
$100K - $120K *
Advance your career by managing audio visual projects from inception to completion, ensuring seamless execution and client satisfaction while collaborating with diverse teams and overseeing logistics...
Yesterday
$110K - $130K *
Shape the future of healthcare by leading complex implementations across provider and payor organizations. Drive project success through collaboration, strategic planning, and innovative solutions whi...
Yesterday
Senior Project Manager, Client Services
$110K - $130K *
Drive client satisfaction as a Senior Project Manager, overseeing eDiscovery projects, managing budgets, and consulting on best practices. Lead teams, enhance workflows, and ensure timely delivery whi...
Today
$110K - $130K *
Lead the charge in overseeing high-impact projects, driving strategic initiatives, and fostering strong customer relationships while ensuring alignment with business objectives and delivering measurab...
Reposted 1 week ago
$140K - $185K *
Transform project delivery by managing IT initiatives for California agencies. Collaborate with state staff to ensure timely, budget-compliant outcomes while leveraging Agile methodologies and large s...
1 week ago
Lead Project Manager, Workplace Operations
$100K - $120K *
Lead the charge in managing workplace design and construction projects, ensuring operational readiness and accountability across multiple sites while optimizing budgets and vendor performance for succ...
3 weeks ago
$110K - $130K *
Engage your expertise to lead bridge and structural projects from planning to completion. Manage multidisciplinary teams, maintain client relationships, and drive practice growth across Massachusetts...
4 days ago
$155K - $210K *
Lead complex programs and strategic client engagements, driving technology transformation and sustainable business value. Act as a trusted adviser to C-level stakeholders, shaping program vision and e...
1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.