Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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1,000+

Director, Project Management Jobs in Pennsylvania

Sort By: Relevance

$84K - $105K *

Drive project success by managing client relationships and leading implementation strategies. Collaborate with teams to assess needs, develop plans, and ensure timely delivery while navigating challen...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$84K - $105K *

Deliver exceptional client engagement by managing project success, assessing needs, and developing strategic plans. Lead cross-functional teams to ensure timely and budget-compliant implementations wh...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Transform your career by leading strategic initiatives and managing program operations. Drive efficiency and effectiveness while aligning objectives with customer goals. Inspire your team and engage w...

Yesterday

  •   8 - 10 years exp.  •   Staffing

$88K - $105K *

Lead a multi-discipline team to shape innovative architectural projects in transportation. Collaborate with clients and governing agencies to ensure compliance and quality, while managing project phas...

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $180K *

Innovate and lead the MyGeotab workflows, ensuring usability and reliability while driving evolution and collaboration across product domains to enhance customer experience and operational efficiency...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Transportation

$108K - $130K *

Drive program delivery across multiple products, ensuring timely outcomes by managing risks, dependencies, and stakeholder priorities. Collaborate cross-functionally to maintain accurate project data...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Pioneer innovative solutions as a Senior Manager in Deployed Engineering, leading hands-on deployments and building a high-performing team. Collaborate closely with customers and internal teams to dri...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the charge in expanding into new healthcare verticals by developing and executing go-to-market strategies, managing partnerships, and driving campaign performance. Collaborate with cross-function...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $160K *

Transform program execution by coordinating large-scale data center initiatives, ensuring alignment across stakeholders, managing risks, and driving milestones to successful completion while fostering...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Business Services

$144K - $216K *

Shape the future of Quality Assurance and Regulatory Affairs solutions. Lead global strategy, governance, and lifecycle management of critical IT systems to ensure compliance, quality, and patient saf...

Reposted 1 month ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$124K - $207K *

Shape the future of risk management by leading analytics and decision support initiatives. Drive the development of key risk indicators and performance metrics, enabling informed decision-making acros...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$124K - $207K *

Join a team that's transforming risk data into actionable insights. Lead analytics and decision support initiatives, manage delivery roadmaps, and enhance team capabilities to drive effective risk man...

Philadelphia, PARemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Optimize project management processes by overseeing estimates, scheduling, and quality control. Collaborate with design teams and clients to ensure project success while maintaining high standards and...

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$120K - $145K *

Unlock potential by driving strategic people initiatives that align with business goals. Collaborate with leaders to enhance employee engagement, performance, and organizational design while fostering...

6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$82K - $153K *

Unlock potential by driving acquisition strategies and building relationships with agency owners. Collaborate with leadership to enhance deal pipelines and support growth initiatives through effective...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Drive your career with impactful project management in bridge engineering. Oversee multi-disciplinary teams, manage budgets, and ensure client satisfaction while delivering quality projects on time an...

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$185K - $231K *

Unlock potential by leading regional service delivery, driving growth and operational excellence across multiple territories. Collaborate with diverse teams to enhance customer satisfaction and optimi...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$121K - $164K *

Champion a team of analysts to enhance enterprise infrastructure services, ensuring reliable support and operational excellence. Collaborate with cross-functional teams to align priorities and drive c...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $105K *

Drive successful project outcomes by leading complex initiatives that align with strategic objectives. Collaborate with stakeholders to manage scope, budget, and compliance while ensuring timely deliv...

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$142K - $197K *

Drive strategic improvements and operational efficiency in Partnerships by establishing frameworks, integrating AI solutions, and optimizing team performance, all while collaborating with cross-functi...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Champion innovative clinical development strategies in General Medicine/Metabolic. Collaborate with cross-functional teams to deliver tailored solutions, leveraging deep therapeutic expertise to drive...

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$111K - $139K *

Champion financial excellence by leading customer P&L development and reporting. Collaborate with sales leadership to drive insights and governance, while developing a high-performing finance team to...

2 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$166K - $249K *

Shape the future of AI in healthcare by defining and executing a strategic roadmap that integrates intelligent solutions into clinical workflows, ensuring safety and efficiency while collaborating wit...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$132K - $261K *

Deliver innovative digital employee experience solutions by leading enterprise-wide initiatives, providing strategic guidance, and enhancing workplace technologies to boost productivity and operationa...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$132K - $261K *

Transform employee experiences by leading digital initiatives, providing strategic guidance, and implementing scalable solutions that enhance productivity and operational efficiency across enterprise...

1 week ago

  •   8 - 10 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.