Explore $100K+ Jobs in Illinois

Find high-paying career opportunities across Illinois with Ladders. Browse vetted professional jobs offering salaries of $100,000 or more, from openings in Chicago to roles in cities and communities throughout the state. Whether you’re ready to take the next step in your career or explore a new industry, discover Illinois positions that match your experience and goals.

Career Opportunities Across Illinois

Illinois offers a broad range of professional opportunities, with a concentration of employers and roles in the Chicago area and opportunities across the rest of the state. Explore positions in fields such as finance, technology, healthcare, manufacturing, consulting, and business leadership. Available roles and compensation vary by employer, location, and experience.

Find a Role That Fits Your Experience

Use Ladders to explore professional openings with salaries of $100,000 or more. Review job details, compare opportunities, and focus your search on the locations, industries, and responsibilities that align with your career plans. Check listings for requirements, work arrangements, and compensation details.

Advance Your Career in Illinois

Start your search for a high-paying job in Illinois by browsing current listings and applying to roles that fit your qualifications. New opportunities can become available over time, so check back regularly to find the latest vetted professional jobs on Ladders.

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$137K - $245K *

Lead the charge in driving strategic initiatives and product innovation within the Telematics Business Unit, enhancing core offerings and exploring new market opportunities through hands-on collaborat...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $124K *

Unlock potential by supporting project execution in thermal power plants. Collaborate across teams to manage workstreams, ensuring timely delivery and adherence to budget while overseeing technical an...

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$214K - $358K *

Shape the future of clinical development by leading cross-functional teams in executing innovative programs. Collaborate with internal and external stakeholders to create, implement and drive cutting...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Lead product strategy and execution, engaging with stakeholders to optimize product lines. Drive design, distribution, and promotion efforts while managing backlogs and ensuring alignment with busines...

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$130K - $190K *

Join us to lead diverse substation projects, ensuring safety, quality, and timely execution while mentoring your team and fostering strong client relationships in a dynamic environment...

5 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Champion operational excellence by leading communication strategies and process improvements. Collaborate with leadership and teams to ensure effective information flow and accountability, driving ini...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $145K *

Drive procurement excellence by establishing strategies that enhance efficiency, manage risk, and optimize spend across diverse categories. Lead sourcing, negotiations, and supplier management to supp...

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$91K - $121K *

Join a team that's pivotal in delivering large-scale PMO projects, managing budgets, schedules, and stakeholder communications. Drive cost control and enhance project performance through expert planni...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$194K - $266K *

Champion patient engagement strategies by leading a dynamic team focused on optimizing recruitment and retention across clinical trials. Drive performance, enhance collaboration, and ensure successful...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the charge in multidisciplinary design delivery for data center projects, ensuring buildable, cost-effective designs from planning through construction. Collaborate with teams to meet tenant need...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$95K - $115K *

Unlock project potential as a Program Manager, leading cross-functional teams to enhance released products, drive strategic initiatives, and ensure alignment with organizational goals in a dynamic, re...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$298K - $340K *

Join a dynamic team to lead strategic statistical programming initiatives, ensuring top-quality deliverables and compliance across diverse clinical trials. Collaborate with cross-functional partners t...

United StatesRemote

Reposted 3 weeks ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$107K - $145K *

Drive growth by identifying and securing new business opportunities in risk management and medical education. Collaborate with teams to develop proposals, manage sales pipelines, and ensure alignment...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Lead and develop engineering teams focused on clinical data integration and insights. Drive the direction of data pipelines and ensure impactful, equitable health outcomes through effective collaborat...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K *

Transform projects by leading a dynamic team, ensuring safety, quality, and financial success from inception to completion while mentoring junior staff and fostering client relationships...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$180K - $215K *

Lead the charge in transforming supply chain technology strategies, driving innovation and operational excellence across S2P and O2C value streams. Collaborate with cross-functional teams to enhance d...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$100K - $120K *

Manage large-scale experiential marketing projects, ensuring strategic planning, flawless execution, and timely delivery while balancing budgets, logistics, and stakeholder expectations in a fast-pace...

4 days ago

  •   8 - 10 years exp.  •   Media

$180K - $230K *

Elevate our data and AI capabilities by owning the semantic layer, defining key metrics, and leading a growing analytics engineering team to ensure consistency across our construction projects...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Elevate the delivery of Salesforce programs by leading end-to-end project management, ensuring compliance, and fostering collaboration across teams to enhance federal application modernization efforts...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Business Services

$112K - $154K *

Elevate healthcare solutions by managing the full lifecycle of innovative diagnostic products. Collaborate cross-functionally to drive market strategies, enhance customer experiences, and ensure succe...

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$203K - $304K *

Champion innovative operational strategies in clinical research, driving excellence in bid defense meetings and proposal development. Collaborate with cross-functional teams to enhance study execution...

United StatesRemote

1 week ago

  •   15+ years exp.  •   Healthcare

$204K - $227K *

Drive transformational aviation infrastructure programs, overseeing large-scale terminal development projects. Lead multidisciplinary teams, ensuring strategic delivery, stakeholder collaboration, and...

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$204K - $227K *

Elevate your career by leading large-scale aviation projects, ensuring strategic delivery and operational excellence. Collaborate with multidisciplinary teams and stakeholders to drive transformationa...

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$85K - $92K *

Unlock your potential by driving complex technical programs and collaborating across global teams. Lead product development from concept to launch while managing diverse priorities in a dynamic enviro...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$135K - $150K *

Champion growth by leading strategic business development initiatives, forging partnerships, and driving revenue expansion. Collaborate with executives to align goals and enhance market presence while...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Technical Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Illinois?question toggle

    Illinois listings may include professional and leadership roles in areas such as finance, technology, healthcare, manufacturing, consulting, and business operations. Job availability and qualifications vary by employer.

  • Are there high-paying jobs outside Chicago?question toggle

    Yes. While many opportunities are based in the Chicago area, listings may also be available in other Illinois cities and communities. Search by location to explore current openings.

  • How can I find Illinois jobs that pay $100,000 or more?question toggle

    Browse Illinois listings on Ladders and review each job’s salary information, qualifications, location, and work arrangement. Listings feature vetted professional opportunities with salaries of $100,000 or more.

  • Do Illinois job listings include remote or hybrid roles?question toggle

    Some listings may offer remote or hybrid work, depending on the employer and position. Check each job description for the specific work arrangement.