Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
$110K - $130K *
Lead the charge in overseeing high-impact projects, driving strategic initiatives, and fostering strong customer relationships while ensuring alignment with business objectives and delivering measurab...
Reposted 2 weeks ago
Director, IT Portfolio Management
$145K - $175K *
Advance your career by leading IT portfolio management strategy, overseeing investment planning, vendor management, and governance. Collaborate with stakeholders to ensure effective delivery and measu...
1 week ago
$135K - $160K *
Lead the charge in quality and validation readiness for complex programs, uniting Engineering, Product, and Customer Success teams. Utilize AI and automation to streamline processes, enhance delivery...
2 days ago
Lead Program Manager, Customer Portfolio
$110K - $130K *
Lead complex product group initiatives, ensuring successful delivery through strategic planning, stakeholder engagement, and cross-team collaboration. Mentor program managers while driving transformat...
3 weeks ago
Senior Technical Program Manager
$127K - $175K *
Champion the execution of security and privacy initiatives, aligning cross-functional teams to reduce risks and enhance outcomes. Drive strategic planning, maintain clear communication, and prepare ex...
5 days ago
$80K - $90K *
Champion project success by managing timelines, resources, and stakeholder communication. Drive seamless implementation experiences while collaborating with cross-functional teams to deliver value-dri...
3 weeks ago
$100K - $200K *
Champion large-scale enterprise application initiatives, leading Agile teams to drive digital transformation, manage program execution, and ensure alignment with strategic objectives while fostering c...
3 weeks ago
$101K - $126K *
Join a dynamic team to lead complex projects, ensuring timely delivery and alignment with strategic goals. Collaborate across departments, manage risks, and mentor others while leveraging best practic...
2 weeks ago
Product Management Senior Advisor
$113K - $188K *
Champion the development of innovative tools for customer service teams, enhancing agent efficiency and service quality. Collaborate across departments to drive product strategy, leveraging data and u...
5 days ago
Director, IT Portfolio Management
$135K - $160K *
Drive your career with a strategic role in IT Portfolio Management, overseeing investment planning, resource governance, and vendor management. Collaborate with stakeholders to ensure effective delive...
5 days ago
$120K - $145K *
Drive impactful program management by leading cross-functional initiatives, ensuring alignment with strategic goals, and delivering measurable results in a dynamic environment. Collaborate effectively...
1 week ago
Research Project Manager, Executive Operations
$75K - $145K *
Empower our leadership team by managing complex operations and enhancing productivity. Collaborate across diverse teams to support high-priority initiatives at the intersection of AI and national secu...
2 weeks ago
Program Manager of Technical Development
$140K - $185K *
Drive technical excellence by developing standards and processes for commissioning, ensuring consistent execution across projects. Collaborate with cross-functional teams to enhance workforce capabili...
1 week ago
$140K - $185K *
Collaborate with cross-functional teams to drive product strategy, manage roadmaps, and enhance customer experiences. Lead product initiatives, ensuring alignment with business goals while mentoring j...
2 weeks ago
Senior Manager, PMO (P&C Insurance)
$140K - $175K *
Lead transformative insurance program initiatives, overseeing technology enhancements and operational workflows. Collaborate across teams to drive project management and ensure compliance, while optim...
Yesterday
$110K - $125K *
Drive the Reuse function within the Product Lifecycle team, ensuring efficient operations, stakeholder communication, and process consistency to support the mission of serving Veterans. Lead a team fo...
2 weeks ago
$110K - $130K *
Transform product strategy in Chemical & Workplace Safety by leading initiatives from discovery to delivery. Collaborate across teams to balance customer needs and business goals, driving measurable o...
3 weeks ago
Project Manager, Client Services
$80K - $95K *
Transform eDiscovery management by driving operational excellence, ensuring timely project delivery, and enhancing workflow efficiency. Collaborate with stakeholders to uphold quality standards and fo...
2 weeks ago
$125K - $225K *
Elevate project success by leading multidisciplinary teams in nuclear design and program management, ensuring safety, quality, and compliance across all phases of construction and operations for compl...
1 week ago
Senior Technical Program Manager
$115K - $275K *
Manage the delivery of GPU clusters for AI workloads by coordinating teams across engineering, networking, and operations. Develop strategies, manage risks, and ensure timely, quality launches to scal...
Reposted 1 week ago
Director, Distribution Strategy
$172K - $203K *
Empower the distribution strategy by designing and managing rate content across channels, ensuring accurate delivery and partner trust. Collaborate with cross-functional teams to build scalable progra...
1 week ago
Executive Director, Statistical Programming
$298K - $340K *
Join a dynamic team to lead strategic statistical programming initiatives, ensuring top-quality deliverables and compliance across diverse clinical trials. Collaborate with cross-functional partners t...
Reposted 3 weeks ago
Director, Enterprise Portfolio Enablement
$110K - $130K *
Drive your career with a strategic role focused on enhancing project management standards and integrating enterprise initiatives. Collaborate with leaders to improve clarity, prioritization, and execu...
3 weeks ago
Product Manager - Foundation Engineering
$158K - $248K *
Champion the development of the product roadmap for Observability and Compute/Network teams, ensuring alignment with reliability goals, system health monitoring, and infrastructure management strategi...
4 weeks ago
Associate Director - Program & Project Management
$120K - $145K *
Drive full lifecycle implementations of Murex upgrades, ensuring effective governance and stakeholder management while leading a team in a dynamic banking technology environment...
2 days ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.