Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$170K - $220K *

Shape strategic business operations by leading pricing strategies, financial analyses, and company planning. Drive decision-making processes, collaborate across teams, and influence key investment dec...

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Take ownership of patient care excellence by leading a dynamic nursing team, ensuring high-quality vascular access procedures, and fostering a supportive environment for both staff and patients in a f...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Lead the charge in shaping innovative therapeutic programs, ensuring operational excellence and regulatory compliance while fostering high-performing clinical teams to achieve exceptional patient outc...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Transform therapeutic programs by leading, coordinating, and enhancing operations to ensure high-quality patient care and optimal outcomes. Collaborate with staff to implement effective strategies and...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$92K - $110K *

Champion the operational excellence of a Radiation Oncology department by managing clinical, administrative, and compliance functions. Lead a dedicated team to enhance patient safety, service quality...

3 days ago

  •   5 - 7 years exp.  •   Staffing

$90K - $114K *

Drive patient engagement by managing care-management service lines, focusing on Remote Patient Monitoring. Lead a team to enhance enrollment, retention, and compliance while collaborating with clinica...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$122K - $177K *

Lead coding operations and education initiatives to ensure compliance, accuracy, and optimal reimbursement across the organization. Manage staff training and oversee coding standards while collaborati...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Champion excellence in surgical care by leading a dynamic team, ensuring operational efficiency, and enhancing patient experiences across multiple specialties in a fast-paced environment...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Unlock potential by leading day-to-day operations in a dynamic Ambulatory Surgery Center. Drive efficiency, enhance patient care, and foster staff development while ensuring compliance and fiscal acco...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$248K - $422K *

Pioneer operational excellence and strategic growth in surgical services. Drive leadership development and financial stewardship across multiple sites, ensuring high-quality care and innovative progra...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Champion clinical education excellence by leading partnerships and ensuring alignment with accreditation standards, enhancing student learning outcomes across nursing programs through strategic oversi...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Lead the charge in enhancing clinical education by overseeing partnerships, ensuring compliance with accreditation standards, and fostering faculty development to elevate student learning outcomes acr...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Lead the charge in enhancing clinical educational experiences by establishing partnerships and aligning nursing programs with accreditation standards. Drive continuous improvement for student success...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Join a team that drives clinical excellence and patient-centered care within a leading Hospitalist Program, overseeing quality outcomes, operations, and staff mentoring while collaborating with key he...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$168K - $231K *

Drive transformation by partnering with cross-functional teams to design and implement effective product operations, ensuring alignment with strategic goals and enhancing organizational effectiveness...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$210K - $250K *

Transform healthcare delivery by leading a dynamic medical team to enhance patient outcomes, implement innovative care models, and drive quality improvements in a collaborative environment focused on...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Shape the future of clinical education by designing and implementing innovative training programs that enhance staff skills and improve patient care outcomes. Collaborate with interdisciplinary teams...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Elevate clinical education by designing and implementing innovative training programs. Collaborate with teams to enhance staff skills, promote best practices, and ensure exceptional patient care throu...

Today

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Help us enhance clinical education by designing and implementing innovative training programs. Collaborate with teams to identify needs, mentor staff, and promote best practices, ensuring exceptional...

Today

  •   Less than 5 years exp.  •   Healthcare

$230K - $250K *

Elevate IT operations by leading service delivery, compliance, and vendor management. Collaborate across departments to ensure GxP systems are validated and inspection-ready while driving strategic IT...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Elevate your career by managing clinical operations in a dynamic surgical environment. Oversee daily activities, enhance patient care, and implement process improvements while collaborating with leade...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$198K - $297K *

Drive comprehensive intellectual property strategies, manage global portfolios, and support cross-functional teams in a dynamic biotech environment. Collaborate on strategic transactions and ensure ro...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Take ownership of a global medical information service, leading a team to establish processes, manage budgets, and ensure compliance. Collaborate across departments to support commercial launches and...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Optimize product delivery by leading a team of Product Owners, ensuring that business needs translate into high-quality, scalable solutions. Collaborate with key stakeholders and champion Agile practi...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Advance product strategy by leading a team of Product Owners to deliver scalable solutions. Champion Agile practices and connect business needs with operational objectives in partnership with key stak...

Morrisville, NCRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.