Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Unit Director - UPMC Williamsport Total Joint & Spine Unit
$100K - $120K *
Shape the future of patient care by leading a dedicated team in a dynamic clinical environment. Drive quality improvements, foster staff engagement, and ensure exceptional outcomes in a specialized or...
Today
Director of Nursing Services/Wellness Director
$140K - $160K *
Lead the charge in delivering top-tier nursing services by overseeing operations, ensuring quality care, and managing a dedicated team in a skilled nursing environment. Drive results through strategic...
3 weeks ago
Director of Nursing Services/Wellness Director
$140K - $160K *
Drive excellence in nursing services by leading, coordinating, and evaluating care programs to ensure compliance and enhance resident well-being in a dynamic long-term care environment...
1 week ago
Senior Manager, Medical Writing
$170K - $200K *
Elevate your career by leading the creation and quality control of regulatory documents. Collaborate with cross-functional teams to ensure scientifically rigorous content that meets regulatory standar...
3 days ago
Senior Director, Global People Operations
$232K - $290K *
Shape the future of global People Operations by leading innovative HR service delivery, enhancing employee experiences, and driving operational excellence in a rapidly scaling biopharmaceutical enviro...
2 weeks ago
$83K - $137K *
Elevate community health by managing clinic operations, inspiring staff, and ensuring quality care. Build relationships, maintain compliance, and drive continuous improvement to enhance service delive...
2 weeks ago
$83K - $137K *
Inspire a dedicated team in managing a community health clinic, ensuring quality care, compliance, and fiscal responsibility while fostering relationships that enhance service delivery and community e...
2 weeks ago
$100K - $120K *
Lead the charge in enhancing rehabilitation operations across multiple facilities. Drive clinical excellence, manage staff, and ensure compliance while fostering a supportive environment for both pati...
2 weeks ago
Assistant Director Supply Chain
$88K - $105K *
Join a team that's transforming supply chain operations by leading daily activities, enhancing performance, and fostering staff development to ensure optimal service delivery and customer satisfaction...
1 week ago
Clinical Operations Manager - Pediatrics
$77K - $120K *
Oversee clinical operations across multiple specialty clinics, ensuring quality patient care and efficient service delivery. Collaborate with teams to enhance performance, manage budgets, and maintain...
2 days ago
Manager - Inpatient Clinical - AAMC
$102K - $154K *
Champion the advancement of substance use disorder services, overseeing the clinical and administrative aspects of Inpatient/Residential units. Lead, support, and develop staff while ensuring complian...
Reposted 3 weeks ago
Designated Pharmacy Manager - Clinical Services Development & Operations
$120K *
Elevate your career by leading pharmacy operations and innovating clinical services. Collaborate cross-functionally to develop scalable healthcare programs that enhance care delivery and meet evolving...
3 weeks ago
$120K - $150K *
Advance strategic partnerships by managing EHR relationships, driving pipeline growth, and enhancing co-sell motions. Collaborate with sales and marketing to optimize partner engagement and ensure mea...
1 week ago
$110K - $130K *
Lead strategic partnerships by managing EHR relationships, driving pipeline growth, and enhancing co-sell motions. Collaborate with sales and marketing to optimize partner engagement and ensure measur...
1 week ago
Program Director, Rehabilitation
$100K - $130K *
Drive the rehabilitation program's success by overseeing operations, enhancing quality, and fostering team development in a collaborative environment focused on superior patient outcomes and community...
1 week ago
Clinical Director of Intake and Assessment Service
$95K - $115K *
Empower patient care by overseeing assessments, ensuring confidentiality, and collaborating with teams to enhance mental health services while tracking performance indicators and training staff for ef...
Reposted 2 weeks ago
Manager / Clinical Alethic Training
$80K - $95K *
Transform your career by leading clinical teams to enhance patient care, ensuring operational excellence and compliance. Drive quality initiatives while fostering a collaborative environment that prio...
Yesterday
Manager / Clinical Alethic Training
$80K - $95K *
Lead clinical operations and staff development to ensure high-quality patient care. Oversee daily functions, drive compliance, and implement safety initiatives while fostering a collaborative environm...
Yesterday
Director, Medical Managed Care
$160K - $200K *
Transform the future of healthcare by leading payer communication strategies, ensuring the delivery of scientific and clinical information for Duchenne muscular dystrophy. Build relationships with key...
2 weeks ago
Clinic Director - Physical Therapist
$100K - $130K *
Lead the charge in enhancing clinical operations and patient care while mentoring a dynamic team. Drive growth through community partnerships and innovative programs in a collaborative, sports-focused...
2 days ago
$300K - $350K *
Empower the organization by providing strategic physician leadership, overseeing clinical operations, and promoting collaboration across departments. Lead transformative initiatives, ensuring complian...
3 weeks ago
Regional Director of Operations
$110K - $130K *
Empower communities by overseeing operations in senior living, driving strategic initiatives, and ensuring quality care. Lead a dedicated team to achieve financial goals while fostering a culture of e...
2 weeks ago
Clinic Director - Growth Manager
$80K - $95K *
Lead a clinic, build a dynamic team, and drive patient-centered outcomes while delivering evidence-based orthopedic care and fostering community relationships...
1 week ago
$110K - $130K *
Drive continuous improvement initiatives by identifying opportunities, developing best practices, and implementing metrics to enhance performance across the business unit, serving as an internal consu...
Today
Associate Director, Analytical Development (Small Molecule)
$161K - $220K *
Join a team that's redefining analytical development for small molecules. Lead projects from method development to regulatory submissions, guiding internal and external partnerships while fostering a...
2 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.