Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$110K - $130K *

Lead the charge in enhancing patient care by overseeing daily operations, implementing process improvements, and fostering a collaborative environment to ensure optimal efficiency and outcomes in an o...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Tackle the challenge of leading clinical operations in an ambulatory surgical center. Oversee staff development, ensure quality assurance, and drive program growth while fostering a collaborative envi...

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Transform patient care by leading nursing operations in a dynamic outpatient surgery center. Oversee clinical management, ensure high-quality care, and foster team development while enhancing operatio...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$144K - $245K *

Lead the design and execution of workforce development programs, ensuring compliance and timely deliverables. Collaborate across teams and stakeholders to create scalable systems that enhance healthca...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$180K - $220K *

Transform the effectiveness of healthcare operations by leading cross-functional teams, fostering strategic partnerships, and driving performance improvement initiatives that enhance patient care and...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$207K - $310K *

Transform incentive compensation operations by leading a global team to ensure accurate payouts, drive process improvements, and enhance seller experiences while collaborating across multiple function...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Empower clinical research initiatives by managing a disease-focused portfolio, leading a dedicated team, and ensuring compliance and efficiency in trial operations while fostering collaboration and st...

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Manage a clinical research portfolio, leading a dedicated team to drive innovative research. Oversee operations, ensure compliance, and collaborate with stakeholders to enhance program success and eff...

Today

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in delivering exceptional nursing care while overseeing staff training, evaluations, and resident assessments. Foster a collaborative environment to enhance patient outcomes and ensure...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Unlock insights as you lead business analytics and intelligence efforts across the California market. Collaborate with cross-functional teams to transform complex data into actionable strategies that...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$208K - $242K *

Join a team that's transforming R&D technology strategy into impactful solutions across clinical, regulatory, and operational domains, ensuring readiness for pivotal development and commercial launch...

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$171K - $231K *

Drive innovative patient recruitment strategies to enhance clinical trial enrollment and retention. Collaborate with cross-functional teams to implement data-driven approaches, optimize patient engage...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$159K - $219K *

Shape the future of small molecule analytical development by leading innovative strategies and guiding a talented team. Collaborate across functions to ensure regulatory readiness and successful comme...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive patient outcomes by leading case management and ensuring accurate data for IRF PPS. Collaborate with clinical teams to enhance care quality and compliance while mentoring staff and managing pati...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Take ownership of clinical management in our ambulatory surgery center, overseeing Pre-Op, PACU, and GI nursing teams to ensure high-quality patient care and operational efficiency while fostering a s...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Shape the future of revenue operations by transforming data into actionable insights. Collaborate with cross-functional teams to enhance performance metrics, streamline reporting, and drive strategic...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $100K *

Optimize program effectiveness by overseeing and enhancing residential and community-based services. Lead quality improvement initiatives and ensure compliance while fostering staff development and pr...

Today

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Accelerate progress at our clinics by overseeing daily operations, ensuring compliance, and supporting financial goals while fostering effective communication between administrative services and clini...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$162K - $244K *

Drive excellence in patient care by managing ICU/SDU operations. Oversee staff, resources, and delivery of services, collaborating across departments for optimal outcomes. Lead efforts in service deve...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$97K - $116K *

Transform healthcare delivery by leading surgical operations and managing clinical teams. Collaborate with professionals to uphold high standards in patient care while ensuring efficient facility oper...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$208K - $250K *

Join a team that's dedicated to delivering exceptional primary care while enjoying a balanced work-life schedule. Contribute your expertise in a supportive environment with ample resources and opportu...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in delivering exceptional pediatric therapy services while mentoring clinical staff, ensuring compliance, and enhancing client care through effective management and oversight of operat...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Take ownership of clinical operations, ensuring high-quality services and compliance while mentoring staff and managing client progress. Collaborate with HR to attract talent and maintain effective tr...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$197K - $255K *

Transform graduate medical education by leading diverse residency and fellowship programs. Oversee operations, ensure compliance, and foster stakeholder relationships to enhance training quality and p...

2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$125K - $150K *

Transform healthcare service delivery by leading teams to optimize client satisfaction, compliance, and operational efficiency in a dynamic, growth-oriented environment focused on best practices and c...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.