Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Medical Director, Early-Stage Clinical Development
$295K - $339K *
Join a team that's dedicated to advancing clinical development strategies for transformative therapies. In this pivotal role, you'll lead cross-functional efforts, mentor professionals, and ensure eff...
1 week ago
Senior Medical Director, Clinical Development
$340K - $368K *
Drive strategic medical leadership in late-stage clinical development, overseeing pivotal programs and ensuring alignment across cross-functional teams. Shape clinical strategies, mentor talent, and e...
2 weeks ago
Director of Clinical Education / Clinical Coordinator
$100K - $120K *
Grow your career by leading clinical education initiatives, ensuring high-quality supervised practice experiences, and supporting PA program accreditation while engaging with students and faculty in a...
1 week ago
Director of Clinical Education / Clinical Coordinator
$80K - $95K *
Support the PA Program by coordinating clinical education, ensuring SCPEs meet standards, and engaging in teaching and advising. Collaborate with faculty to enhance experiential learning and maintain...
1 week ago
$119K - $142K *
Join a team that's redefining digital operations by leading strategic initiatives, enhancing customer experiences, and driving growth in a fast-paced environment. Shape the future of MODAL Digital whi...
2 weeks ago
Executive Director - Baton Rouge, LA
$110K - $130K *
Empower the success of our PACE Organization by leading operations, strategic initiatives, and team development to provide exceptional care for the elderly. Ensure compliance and financial viability a...
Reposted 6 days ago
Executive Director - Baton Rouge, LA
$110K - $130K *
Lead the development and operations of PACE programs ensuring quality care for seniors while managing compliance, finances, and staff development. Collaborate with teams to enhance service delivery an...
Reposted 6 days ago
Senior Manager, Medical Affairs Operations
$165K - $190K *
Optimize Medical Affairs operations by managing budgets, contracts, and timelines. Collaborate cross-functionally to ensure compliance and timely execution of MAF activities, including advisory boards...
1 week ago
Senior Manager, Medical Affairs Operations
$165K - $190K *
Drive operational excellence in Medical Affairs by managing processes, timelines, and cross-functional coordination to ensure timely execution of strategic initiatives while maintaining compliance and...
1 week ago
Manager, Practice Accounting (OpEx)
$95K - $115K *
Transform the future of practice accounting by leading a dynamic team, ensuring compliance with US GAAP, and fostering strong relationships with stakeholders to drive financial excellence across multi...
3 days ago
Director of Program Management
$135K - $160K *
Transform your career by leading cross-functional teams to drive drug development strategies. Collaborate with key stakeholders to ensure successful execution of integrated plans, manage risks, and de...
4 days ago
Medical Director - Critical Care
$300K - $309K *
Transform patient care by leading medical strategy and clinical innovation. As a vital member of the team, you'll guide product development and trial execution while engaging with key stakeholders to...
Reposted 2 weeks ago
$104K - $110K *
Unlock potential by leading the clinical launch and growth of a new Propel clinic. Blend hands-on clinical excellence with strategic leadership to ensure high-quality care, team development, and susta...
Today
Senior Associate, Pharmacovigilance Coordinator
$100K - $115K *
Advance your career by managing daily Pharmacovigilance operations, ensuring timely safety data handling, and supporting compliance efforts within a dynamic team focused on patient safety and regulato...
Reposted 1 week ago
Associate Vice President, Operations
$125K - $150K *
Empower operational excellence by leading a diverse team to enhance clinical value and service delivery across multiple markets, ensuring financial performance and strategic growth through strong rela...
1 week ago
Director of Clinical Services - Behavioral Health - LCSW/LPC
$100K - $120K *
Shape the future of mental health services by leading clinical strategies and ensuring high-quality patient care. Collaborate with a dedicated team to enhance treatment programs and achieve institutio...
1 week ago
$110K - $120K *
Transform patient care by leading clinical operations and supporting your team. Collaborate with healthcare professionals to ensure high-quality home care, while driving compliance and continuous impr...
2 weeks ago
Associate Director, Clinical Supply Project Manager - Program - Hybrid
$142K - $224K *
Elevate clinical supply management by leading strategic planning and execution for clinical trials. Collaborate with cross-functional teams to ensure timely delivery and optimal supply chain solutions...
4 days ago
Associate Director, Clinical Supply Project Manager - Program - Hybrid
$142K - $224K *
Drive strategic clinical supply planning and execution for global trials, ensuring seamless coordination across teams. Lead project management efforts, mitigate risks, and optimize supply chain proces...
4 days ago
$110K - $130K *
Reimagine cancer care by leading a comprehensive program that enhances patient experience, fosters collaboration, and drives operational excellence across oncology, infusion, and radiation services wi...
3 weeks ago
$214K - $241K *
Champion clinical study success by providing scientific expertise and cross-functional collaboration, ensuring efficient execution of Clinical Development Plans from Phase I to III trials...
Reposted 2 weeks ago
$130K - $160K *
Lead the charge in ensuring efficient operations and staffing of Surgery Centers, while upholding clinical best practices. Collaborate with physicians and management to enhance patient care and develo...
1 week ago
Director, Surgical and Perioperative Services-(UPMC Harrisburg)
$120K - $145K *
Drive quality patient care by refining clinical processes and operations. Collaborate with leadership to enhance patient outcomes and staff satisfaction while ensuring compliance with regulatory stand...
Today
$89K - $104K *
Reimagine rehabilitation services by leading and mentoring teams, ensuring high standards and compliance, and managing key operations for multiple accounts. Drive team growth and uphold integrity whil...
Reposted 3 weeks ago
Associate Director, Global Regulatory Affairs, Compliance and Project Management
$185K - $205K *
Collaborate across functions to design regulatory strategies that ensure compliance, support development programs, and facilitate high-quality submissions. Play a pivotal role in navigating complex re...
Reposted 4 weeks ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.