Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
Director, Member Services, Medicaid
$156K - $215K *
Transform quality engineering practices by leading strategic initiatives across technology portfolios, enhancing delivery quality, and fostering team performance through innovative automation and AI i...
3 days ago
Director, Member Services, Medicaid
$156K - $215K *
Champion quality engineering excellence across diverse technology portfolios, leading teams to enhance delivery quality, automate testing, and drive continuous improvement. Collaborate with cross-func...
3 days ago
Director, Member Services, Medicaid
$156K - $215K *
Shape the future of quality engineering by leading strategic initiatives across technology portfolios. Drive team performance, embed quality practices, and enhance delivery speed and stability through...
3 days ago
Director RN, Emergency Department & Med/Surg
$100K - $120K *
Lead the Emergency Department and Med Surg operations, ensuring high-quality, cost-effective clinical services while managing budgets, staffing, and compliance. Drive performance improvement and foste...
Today
Medical Director, Safety Sciences
$272K - $336K *
Empower clinical advancements as you lead safety strategy and oversight. Drive complex safety assessments, manage cross-functional decision-making, and contribute to vital benefit-risk evaluations acr...
3 weeks ago
Solution Operations Associate Director
$86K - $239K *
Lead the charge in translating product strategy into scalable operational processes, ensuring alignment across teams and enhancing client service delivery through continuous improvement and effective...
1 week ago
Solution Operations Associate Director
$86K - $239K *
Shape operational excellence by translating product strategy into scalable processes. Collaborate across teams to enhance client delivery, drive continuous improvement, and ensure alignment in service...
1 week ago
Associate Director, Business Process Management & Operational Excellence
$170K - $200K *
Drive operational excellence by translating strategy into actionable initiatives, enhancing business processes, and leading cross-functional projects to foster growth and improve execution readiness i...
1 week ago
Director or Senior Director, CMC Protein Biologics
$200K - $275K *
Pioneer innovative CMC strategies for biologics, leading complex antibody programs from candidate selection to IND filing. Collaborate with CROs/CDMOs to ensure quality and efficiency in development...
1 week ago
$95K - $115K *
Lead the charge in enhancing nursing education through innovative simulation experiences, ensuring quality outcomes and faculty support while fostering a collaborative learning environment for student...
Today
Manager Clinical Research-Office of Clinical & Community Trials
$83K - $137K *
Lead the charge in clinical research management, overseeing staff and operations while ensuring compliance with regulations. Collaborate with multidisciplinary teams to drive research initiatives and...
1 week ago
Associate Director, Field Launch & Change Surge
$145K - $270K *
Drive stability by providing surge support for product launches and critical changes, ensuring effective execution and alignment across operations. Collaborate with teams to enhance readiness and swif...
Reposted 1 week ago
$118K - $170K *
Transform clinical operations by leading inpatient surgical units, ensuring excellence in patient-centered care, resource management, and quality improvement while fostering a collaborative environmen...
3 days ago
$118K - $170K *
Grow your career with a leadership role focused on enhancing patient-centered care. Drive operational excellence, manage resources, and foster a collaborative environment to achieve strategic goals in...
3 days ago
$118K - $170K *
Deliver excellence in patient care by leading operations, managing resources, and enhancing quality within clinical services. Drive workforce development, implement best practices, and support strateg...
3 weeks ago
Associate Director, Operations and Escalations Pharmacist
$132K - $193K *
Shape the future of pharmacy operations by leading prescription escalations, ensuring patient safety, and optimizing workflows in a dynamic, direct-to-patient environment. Collaborate across teams to...
3 days ago
Director, Ligand Binding Assays
$125K - $150K *
Shape the future of bioanalytical science by leading Ligand Binding Assay teams, driving innovation, ensuring regulatory compliance, and fostering collaboration across multiple sites to enhance drug d...
2 weeks ago
Medical Director, Clinical Development, Endocrinology
$284K - $385K *
Lead clinical trials in endocrinology, ensuring high-quality study design and execution. Collaborate with cross-functional teams to advance research goals while overseeing patient safety and regulator...
4 days ago
Medical Director, Clinical Development, Endocrinology
$284K - $385K *
Shape the future of clinical trials by leading innovative study designs and ensuring patient safety. Collaborate with cross-functional teams to drive impactful research in endocrinology and rare disea...
4 days ago
$110K - $130K *
Champion the patient marketing strategy, guiding prospects to enrollment and engagement. Collaborate with leadership to optimize channels and messaging, ensuring a seamless patient journey while drivi...
1 week ago
$122K - $165K *
Shape the future of urgent care by providing strategic and operational leadership across multiple locations, ensuring high-quality, patient-centered care while enhancing efficiency and regulatory comp...
Today
Unit Director - 3G Behavioral Health
$85K - $100K *
Empower exceptional patient care as you lead a dynamic team, operations, and clinical initiatives, fostering a collaborative environment focused on healing and continuous improvement in a behavioral h...
3 weeks ago
$108K - $147K *
Transform operations by leading complex projects and initiatives, ensuring strategic alignment across teams. Drive continuous improvement and foster collaboration to enhance facilities and services, s...
2 days ago
$83K - $99K *
Empower rehabilitation excellence by leading a dynamic therapy team, overseeing operations, and enhancing patient care in a skilled nursing facility. Drive program development and ensure compliance wh...
Today
$83K - $99K *
Unlock potential by leading a dynamic rehab team in a skilled nursing facility. Oversee operations, manage staff, and develop therapy programs while ensuring quality patient care and compliance with i...
Today
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.