Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$135K - $160K *

Join a dynamic team as you lead administrative support across multiple offices, ensuring high-quality service delivery, managing talent, and driving operational excellence to meet evolving business ne...

2 days ago

  •   11 - 15 years exp.  •   Business Services

$125K - $150K *

Empower operational excellence by leading administrative support across teams. Drive service delivery, enhance manager effectiveness, and ensure high-quality execution while fostering collaboration an...

2 days ago

  •   11 - 15 years exp.  •   Business Services

$88K - $105K *

Empower clinical excellence by directing and managing comprehensive treatment services for substance use disorders, ensuring compliance and quality across inpatient and outpatient programs while foste...

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$152K - $190K *

Lead the charge in establishing a scalable design capability, overseeing design quality, workflows, and resource planning. Collaborate with cross-functional teams to enhance digital experiences while...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Elevate your career by leading clinical trial management teams, ensuring quality and compliance in monitoring strategies. Collaborate with cross-functional teams to optimize clinical operations and dr...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$240K - $280K *

Transform your career by leading a dynamic sales team to drive growth and exceed targets in a key regional market. Utilize strategic insights and analytics to optimize performance and ensure complianc...

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $210K *

Unlock potential by leading clinical supply chain strategies across multiple global development programs, ensuring investigational products meet patient needs while optimizing resources and compliance...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$175K - $200K *

Lead the charge in optimizing biomarker program operations, ensuring seamless sample processing from collection to storage. Collaborate across teams to uphold quality and compliance while driving grow...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$93K - $104K *

Optimize rehabilitation services by managing DORs, ensuring compliance, and delivering high-quality patient care while driving profitability and operational excellence across multiple accounts...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Lead the charge in clinical excellence by mentoring BCBAs and RBTs, overseeing ABA service delivery, and fostering collaboration with families to enhance client outcomes and team development in a supp...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Reimagine clinical leadership as you oversee ABA services, mentor clinicians, and enhance client outcomes. Drive quality care and foster collaboration in a supportive environment while advancing your...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $192K *

Contribute to a safe and efficient surgical environment by leading nursing operations, ensuring compliance with standards, and enhancing patient care through effective management and staff training...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Empower project delivery excellence by leading cross-functional teams, enhancing client satisfaction, and driving innovation in project management strategies to achieve organizational goals and improv...

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$147K - $175K *

Develop and lead clinical science activities for assigned studies, ensuring cross-functional collaboration and timely issue resolution. Drive protocol development, data review, and regulatory input wh...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$129K - $184K *

Elevate clinical data management by overseeing data integrity and quality across studies. Collaborate with cross-functional teams and vendors to ensure timely delivery of clinical data analyses, drivi...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$238K - $341K *

Transform patient care by leading a dedicated team of primary care providers, enhancing clinical quality and operational efficiency while ensuring exceptional patient outcomes and satisfaction in a dy...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Join an innovative team as you lead operational excellence initiatives to enhance production efficiency, drive continuous improvement, and foster a culture of accountability. Collaborate across depart...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Join a dedicated team leading clinical operations, ensuring quality patient care, regulatory compliance, and efficient service delivery across multiple locations. Collaborate with professionals to enh...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Take ownership of strategic operations in ambulatory care, ensuring high-quality services while collaborating with diverse stakeholders to drive performance, enhance patient experience, and lead impac...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$83K - $88K *

Lead the charge in enhancing resident care by overseeing clinical services, ensuring compliance, and fostering a supportive environment for staff and families. Your expertise will shape the quality of...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$195K - $277K *

Lead the design and execution of clinical oncology studies, collaborating with cross-functional teams to ensure compliance and scientific integrity. Drive project progress and contribute to regulatory...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$195K - $277K *

Drive innovative clinical oncology studies by designing protocols, collaborating with teams, and ensuring compliance with regulations. Leverage expertise to analyze data, support publications, and mai...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $200K *

Drive impactful change in healthcare consulting by leveraging your expertise in clinical operations and research administration. Collaborate with executive leaders to solve complex challenges and fost...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$82K - $108K *

Empower your career by managing and advancing clinical research initiatives. Collaborate with leadership and stakeholders to facilitate trials and grants while ensuring compliance and oversight, foste...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$174K - $292K *

Lead the charge in clinical pharmacology strategy and execution, influencing drug development through expert guidance and collaboration on integrated plans and regulatory interactions for innovative t...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.