Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.
Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.
Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.
Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.
Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.
$225K - $240K *
Architect innovative clinical strategies and collaborate with cross-functional teams to drive the execution and analysis of clinical studies, ensuring high-quality data delivery and alignment with dev...
1 week ago
Clinical Director, Oncology Early Development
$255K - $402K *
Lead clinical research efforts in Early Oncology, managing all phases from study design to regulatory reporting. Collaborate with cross-functional teams to ensure the successful execution and analysis...
Reposted 1 week ago
Clinical Director, Oncology Early Development
$255K - $402K *
Oversee and innovate clinical research activities for Early Oncology. Engage in all phases of development from design to publication. Collaborate with multidisciplinary teams to ensure effective execu...
Reposted 1 week ago
$130K - $150K *
Drive operational excellence by overseeing day-to-day functions and enhancing processes to ensure high-quality deliverables. Collaborate across teams to boost performance and elevate patient satisfact...
Reposted yesterday
Associate Director, Data Operations and Issue Mangement Lead
$152K - $283K *
Shape the future of data operations by leading efforts to enhance system stability and trust in enterprise data. Collaborate with cross-functional teams to resolve issues, drive continuous improvement...
3 weeks ago
Associate Director, Data Operations and Issue Mangement Lead
$152K - $283K *
Drive operational excellence in data operations, ensuring stability and trust. Collaborate cross-functionally to resolve issues and enhance data quality while maintaining scalability. Lead continuous...
3 weeks ago
Senior Operational Strategy Director
$203K - $304K *
Champion innovative operational strategies in clinical research, driving excellence in bid defense meetings and proposal development. Collaborate with cross-functional teams to enhance study execution...
1 week ago
Administrative Director, Division of Therapeutic Development, Intervention, and Evaluation
$124K - $180K *
Join a pioneering team to lead strategic operations in a dynamic healthcare division, driving innovation and excellence in therapeutic development and evaluation while managing a diverse workforce and...
5 days ago
Administrative Director, Division of Therapeutic Development, Intervention, and Evaluation
$124K - $180K *
Develop and execute strategic initiatives for a leading healthcare division, overseeing operations, research, and education. Collaborate with executive leadership to enhance performance and drive inno...
5 days ago
Associate Director, Clinical Supply Management
$174K - $204K *
Execute global clinical supply chain strategies, ensuring operational excellence in demand planning, inventory management, and compliance. Lead a team, manage cross-functional partnerships, and drive...
1 week ago
$110K - $130K *
Drive innovation in nursing practice by leading program development, enhancing clinical standards, and fostering transformational leadership to ensure quality patient outcomes and staff excellence acr...
1 week ago
Clinical Partnerships Lead (Medical Director)
$200K - $250K *
Join us to lead clinical partnerships, influence medical practices, and shape innovative strategies. Use your medical expertise to enhance patient access and drive company growth while collaborating w...
Reposted 3 weeks ago
Associate Director, Clinical Supply Management
$174K - $204K *
Advance global clinical supply chain excellence by leading strategy execution, optimizing inventory, and managing cross-functional partnerships. Drive operational improvements and team development whi...
1 week ago
Director - Clinical Research Physician - GPS Medical
$201K - $360K *
Lead safety initiatives by shaping the future of pharmacovigilance, driving oversight, managing risks, and collaborating across teams to enhance product safety throughout the lifecycle, fostering inno...
3 weeks ago
Associate Director of Operations, House Calls
$100K - $120K *
Lead the charge in optimizing daily operations for our House Calls division, ensuring efficient scheduling, provider assignments, and patient care. Collaborate with clinical teams to enhance service d...
1 week ago
Director Of Clinical Excellence
$100K - $120K *
Drive clinical excellence by leading operations, enhancing patient care, and optimizing workflows. Collaborate with teams to ensure compliance and foster a culture of continuous improvement across mul...
3 weeks ago
Clinical Director of Inpatient and Residential Services
$90K - $110K *
Unlock potential by providing strategic leadership for inpatient and residential behavioral health services. Ensure high-quality, patient-centered care while collaborating with diverse teams and manag...
6 days ago
National Director, Integrated Specialty Practices
$160K - $200K *
Drive strategic growth and business development for National Accounts in Urology and Oncology, optimizing resources and leading negotiations to enhance healthcare outcomes through innovative diagnosti...
2 weeks ago
Senior Director, Translational Medicine
$175K - $210K *
Elevate our translational medicine strategy by leading biomarker and clinical integration efforts, ensuring impactful connections between preclinical insights and clinical outcomes in IBD. Collaborate...
2 days ago
Senior Director, Translational Medicine
$180K - $220K *
Champion the translational strategy linking prifemilast's mechanism to clinical outcomes in IBD. Lead biomarker and pharmacodynamic strategies, collaborating with cross-functional teams to drive impac...
2 days ago
$120K *
Lead the nursing and personal care services, ensuring compliance with regulations while fostering a culture of safety and quality improvement. Collaborate with teams to deliver resident-centered care...
Today
Senior Director, Marketing Operations
$160K - $200K *
Accelerate progress at the intersection of strategy and operations, driving high-performance marketing systems and data governance. You'll partner closely with executive leadership to optimize revenue...
Reposted 3 weeks ago
$125K - $150K *
Lead the charge in clinical operations, enhancing patient care and workflows while collaborating with a founding team to innovate telehealth services in dermatology and women's health. Balance patient...
1 week ago
Senior Director, Program Management
$256K - $283K *
Join a team that's shaping the future of RNA therapeutics by leading cross-functional drug development programs. Drive program strategy and execution while fostering collaboration across Research, Cli...
3 weeks ago
Service Line Clinical Resource Director
$108K - $130K *
Lead strategic initiatives for clinical service lines, enhancing performance and cost efficiency through expert analysis and collaboration with stakeholders to optimize outcomes and standardization ac...
3 days ago
What does a Director of Clinical Operations do?
A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.
What qualifications are typically required for Director, Clinical Operations jobs?
Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.
Where do Directors of Clinical Operations work?
They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.
How much do Director, Clinical Operations jobs pay?
Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.
How can I find Director, Clinical Operations jobs?
Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.