Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$225K - $240K *

Architect innovative clinical strategies and collaborate with cross-functional teams to drive the execution and analysis of clinical studies, ensuring high-quality data delivery and alignment with dev...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$255K - $402K *

Lead clinical research efforts in Early Oncology, managing all phases from study design to regulatory reporting. Collaborate with cross-functional teams to ensure the successful execution and analysis...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$255K - $402K *

Oversee and innovate clinical research activities for Early Oncology. Engage in all phases of development from design to publication. Collaborate with multidisciplinary teams to ensure effective execu...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Drive operational excellence by overseeing day-to-day functions and enhancing processes to ensure high-quality deliverables. Collaborate across teams to boost performance and elevate patient satisfact...

Columbia, MDRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$152K - $283K *

Shape the future of data operations by leading efforts to enhance system stability and trust in enterprise data. Collaborate with cross-functional teams to resolve issues, drive continuous improvement...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$152K - $283K *

Drive operational excellence in data operations, ensuring stability and trust. Collaborate cross-functionally to resolve issues and enhance data quality while maintaining scalability. Lead continuous...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$203K - $304K *

Champion innovative operational strategies in clinical research, driving excellence in bid defense meetings and proposal development. Collaborate with cross-functional teams to enhance study execution...

United StatesRemote

1 week ago

  •   15+ years exp.  •   Healthcare

$124K - $180K *

Join a pioneering team to lead strategic operations in a dynamic healthcare division, driving innovation and excellence in therapeutic development and evaluation while managing a diverse workforce and...

5 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$124K - $180K *

Develop and execute strategic initiatives for a leading healthcare division, overseeing operations, research, and education. Collaborate with executive leadership to enhance performance and drive inno...

5 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$174K - $204K *

Execute global clinical supply chain strategies, ensuring operational excellence in demand planning, inventory management, and compliance. Lead a team, manage cross-functional partnerships, and drive...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive innovation in nursing practice by leading program development, enhancing clinical standards, and fostering transformational leadership to ensure quality patient outcomes and staff excellence acr...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $250K *

Join us to lead clinical partnerships, influence medical practices, and shape innovative strategies. Use your medical expertise to enhance patient access and drive company growth while collaborating w...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$174K - $204K *

Advance global clinical supply chain excellence by leading strategy execution, optimizing inventory, and managing cross-functional partnerships. Drive operational improvements and team development whi...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$201K - $360K *

Lead safety initiatives by shaping the future of pharmacovigilance, driving oversight, managing risks, and collaborating across teams to enhance product safety throughout the lifecycle, fostering inno...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in optimizing daily operations for our House Calls division, ensuring efficient scheduling, provider assignments, and patient care. Collaborate with clinical teams to enhance service d...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Drive clinical excellence by leading operations, enhancing patient care, and optimizing workflows. Collaborate with teams to ensure compliance and foster a culture of continuous improvement across mul...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Unlock potential by providing strategic leadership for inpatient and residential behavioral health services. Ensure high-quality, patient-centered care while collaborating with diverse teams and manag...

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$160K - $200K *

Drive strategic growth and business development for National Accounts in Urology and Oncology, optimizing resources and leading negotiations to enhance healthcare outcomes through innovative diagnosti...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Elevate our translational medicine strategy by leading biomarker and clinical integration efforts, ensuring impactful connections between preclinical insights and clinical outcomes in IBD. Collaborate...

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Champion the translational strategy linking prifemilast's mechanism to clinical outcomes in IBD. Lead biomarker and pharmacodynamic strategies, collaborating with cross-functional teams to drive impac...

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K *

Lead the nursing and personal care services, ensuring compliance with regulations while fostering a culture of safety and quality improvement. Collaborate with teams to deliver resident-centered care...

Toronto, ONIn-Person

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$160K - $200K *

Accelerate progress at the intersection of strategy and operations, driving high-performance marketing systems and data governance. You'll partner closely with executive leadership to optimize revenue...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Lead the charge in clinical operations, enhancing patient care and workflows while collaborating with a founding team to innovate telehealth services in dermatology and women's health. Balance patient...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$256K - $283K *

Join a team that's shaping the future of RNA therapeutics by leading cross-functional drug development programs. Drive program strategy and execution while fostering collaboration across Research, Cli...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Lead strategic initiatives for clinical service lines, enhancing performance and cost efficiency through expert analysis and collaboration with stakeholders to optimize outcomes and standardization ac...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.