Director, Clinical Operations Jobs

Explore Director, Clinical Operations opportunities for experienced leaders who guide the planning and delivery of clinical research. These roles oversee teams, processes, budgets, and vendor relationships to help clinical trials run efficiently while meeting quality, regulatory, and business goals. Ladders features vetted professional jobs with salaries of $100,000 or more.

What Does a Director of Clinical Operations Do?

Directors of Clinical Operations shape operational strategy across clinical programs and studies. They may lead study planning and execution, manage clinical operations teams, monitor timelines and budgets, oversee CRO and site partnerships, and establish processes for consistent trial delivery. The scope varies by employer, therapeutic area, and organization size.

Qualifications and Skills

Employers commonly seek substantial clinical research experience, a record of leading teams or complex studies, and a strong understanding of clinical trial operations and applicable regulations. Relevant strengths can include project and portfolio management, budget oversight, risk assessment, vendor management, communication, and the ability to collaborate across clinical, medical, regulatory, data, and quality teams. Requirements differ by role; some positions prefer an advanced degree or therapeutic-area expertise.

Career Opportunities and Work Settings

Director-level clinical operations professionals work at biotechnology and pharmaceutical companies, contract research organizations, medical device firms, and other research organizations. Depending on the role, responsibilities may span a single study, a regional team, or a broad clinical development portfolio. Search current openings to compare leadership scope, work arrangements, and employer needs.

Find Director, Clinical Operations Jobs on Ladders

Use Ladders to discover vetted Director, Clinical Operations jobs paying $100,000 or more. Review role requirements and compensation details, then identify opportunities aligned with your clinical research leadership experience and career goals.

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$138K - $231K *

Lead revenue cycle operations for a multi-site Center of Excellence, driving performance improvements, managing budgets, and mentoring teams to enhance billing accuracy and cash collections while ensu...

Texas, USRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Transform strategic initiatives into actionable plans by partnering with leadership to drive growth, operational excellence, and business transformation in a dynamic healthcare environment. Engage in...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive strategic leadership in clinical and nursing research operations, enhancing evidence-based practices and fostering collaboration across interdisciplinary teams to improve patient and organizatio...

6 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$145K - $165K *

Lead the charge in clinical operations, overseeing patient care teams and ensuring compliance with regulations while managing administrative duties and budgetary oversight in a dynamic healthcare envi...

Today

  •   5 - 7 years exp.  •   Healthcare

$120K - $140K *

Unlock potential by leading clinical operations in hospice care. Oversee patient services, manage teams, and ensure compliance with regulations while driving quality care and operational excellence in...

Today

  •   5 - 7 years exp.  •   Healthcare

$234K - $251K *

Join a dynamic team as you lead clinical data management strategies, ensuring data integrity and compliance across multiple studies. Collaborate with cross-functional teams to drive quality and effici...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$160K - $165K *

Lead the charge in developing and managing Quality Improvement projects, collaborating with healthcare providers, and analyzing clinical practices to enhance patient outcomes and implement best practi...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Join a visionary team to lead operational excellence in clinical education, driving performance and innovation within a dynamic network. Shape the future of graduate medical education while prioritizi...

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$285K - $296K *

Elevate clinical data systems and programming by leading strategic initiatives, ensuring compliance, and optimizing technology platforms for efficient clinical trials. Collaborate across teams to driv...

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Champion the strategy and execution of clinical data management, ensuring data integrity and compliance for global marketing applications. Lead a dynamic team, oversee vendor relationships, and drive...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Lead the charge in enhancing medical management for post-acute care, ensuring timely clinical decisions and effective case reviews. Collaborate with providers to uphold medical necessity standards and...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $150K *

Unlock operational excellence by leading multi-site Ambulatory Surgery Centers. Drive growth strategies, optimize performance, and foster strong partnerships with physician leaders while managing sign...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$122K - $177K *

Unlock potential by leading HRIS strategy and optimization, overseeing a team to enhance Workday and UKG systems. Drive transformation and collaboration across HR, Finance, and Operations for impactfu...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Drive operational excellence across Mosaic Clinics by enhancing services, ensuring quality care, and fostering partnerships. Collaborate with leadership to achieve financial and service goals while co...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Shape the future of hospice care by leading operations and ensuring high-quality patient experiences. Drive a dedicated team while managing services in a supportive environment with opportunities for...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Explore a leadership role guiding clinical teams to enhance patient care. Drive effective programming, conduct audits, and ensure compliance with standards while collaborating on integrated outpatient...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $105K *

Advance holistic health initiatives for adolescents, oversee integrated wellness operations, and lead a dedicated team to deliver comprehensive care and innovative programming aligned with strategic g...

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $140K *

Empower growth by leading clinical operations, mentoring staff, and enhancing community relationships in a state-of-the-art clinic focused on innovative patient care and operational excellence...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $140K *

Lead the charge in clinical and operational excellence at our Ossining clinic. Mentor staff, cultivate community relationships, and drive growth through innovative care plans and marketing strategies...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Transform healthcare delivery by leading a dedicated team of Providers and RN Case Managers, ensuring compliance and excellence in patient care across long-term care facilities while driving innovativ...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$295K - $311K *

Join a team that's shaping the future of drug safety! Provide operational leadership across pharmacovigilance functions, oversee compliance and vendor relationships, and ensure high-quality safety rep...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Transform the operational landscape of multiple healthcare centers, ensuring exceptional service quality, financial performance, and resource efficiency while enhancing patient experiences across 4-10...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Lead the charge in optimizing operations across multiple urgent care centers, ensuring exceptional patient experiences, efficient resource utilization, and strong financial performance while fostering...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Join us in leading operational excellence across multiple healthcare centers, ensuring top-notch patient experiences and efficient service delivery while managing resources and team dynamics effective...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Advance your career by overseeing operations across multiple healthcare centers, ensuring quality service delivery, financial performance, and a superior patient experience while fostering a motivated...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does a Director of Clinical Operations do?question toggle

    A Director of Clinical Operations leads the planning and execution of clinical research operations. Responsibilities may include managing teams, study timelines and budgets, site and vendor relationships, operational processes, and compliance with applicable requirements.

  • What qualifications are typically required for Director, Clinical Operations jobs?question toggle

    Employers generally look for significant clinical research experience and demonstrated leadership in clinical trial operations. Knowledge of trial regulations, project management, budgeting, vendor oversight, and cross-functional collaboration is often valuable. Specific education and experience requirements vary.

  • Where do Directors of Clinical Operations work?question toggle

    They may work for pharmaceutical and biotechnology companies, contract research organizations, medical device firms, and other organizations conducting clinical research.

  • How much do Director, Clinical Operations jobs pay?question toggle

    Compensation varies by employer, location, experience, and role scope. Ladders focuses on vetted professional opportunities paying $100,000 or more; check each listing for its stated compensation and details.

  • How can I find Director, Clinical Operations jobs?question toggle

    Browse current listings on Ladders and compare job responsibilities, qualifications, work arrangements, and compensation to find roles that match your experience and career goals.